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Biomedical subjects

G Theodossiadis

Publications and source records attributed to G Theodossiadis.

At least 19 recordsLinked to original sources
PubMed1979

How do tears drain? Technetium studies.

We examined the tear drainage system of twenty-fiv normal volunteers by scintillography with Technetium Tc 99m (Pertechnetate). We photographed the changes occurring in the lacrimal sac and nasolacrimal duct during closure and opening of the eyelids. Our findings support Jones' views of normal tear drainage. The tracer was concentrated in the lacrimal sac while the lids were closed for 3 minutes and descended into the nasolacrimal duct as soon as they opened.

Eyelids↗
PubMed1979

[Clinical and pathologic-anatomical results following the application of a mobile argon-laser beam in aphakic pupillary block glaucoma (author's transl)].

In the last four years we have treated with the mobile argon-laser beam 25 cases of aphakic pupillary block glaucoma (p. b. g.). According to the time of manifestation of the p. b. g. the patients were divided into an "early" and a "late" group. In the "early" group (17 eyes) the glaucoma manifested itself 1--4 days after cataract extraction. In the "late" group (8 eyes) p. b. g. appeared from 4 weeks to 3 years after cataract extraction. In 14 of the 17 cases of the first group we achieved a prompt reformation of the anterior chamber and a considerable decrease of intraocular pressure immediately after laser application. In 3 cases of the first group, where the pupil was under relative or absolute mydriasis before argon-laser treatment, the mobile laser beam failed to produce satisfactory results. In all of the 8 patients of the "late" group a reformation of the anterior chamber was achieved, but in only 4 of them did i. o. pressure normalize owing to extensive anterior synechiae. Laser application left either very slight or no traces at all on the iris. In order to ascertain the actual effect of the laser beam upon the iris, we applied laser under identical conditions in eyes which had no glaucoma but were to undergo enucleation because of choroidal melanoma. The histological examination revealed a slight degree of hyperaemia of the iris as an oedema of the connective tissue, while the iris sphincter did not appear to be affected by laser treatment.

Aged↗
PubMed1977

Management of aphakic pupillary block. A new argon-laser approach.

This communication concerns 9 cases of aphakic pupillary block with high intraocular pressure, which were managed successfully by means of a new argon-laser technique. This new approach consisted in the application at the collarette zone of the iris, 1.5 mm from the pupillary border, of a mobile argon-laser beam of variable intensity, ranging from 250 to 500 mW, of constant time (0.5 sec) and of fixed spot size (200 micron m). In some instances the beam was moved parallel and in other cases vertically to the pupillary border in the direction towards the ciliary portion of the iris. This technique ensures maximum retraction of the pupillary border, corresponding to the line of application, coupled with the least possible damage to the iris and a minimum of applications. Simultaneously with the retraction the posterior synechiae of the iris are detached and the outflow of the aqueous trapped in the posterior chamber released.

Cataract Extraction↗
PubMed1977

[Changes of the corneal thickness after cataract extration (author's transl)].

A study of changes of the corneal thickness after cataract extraction was carried out on 149 patients. Cataract extraction was performed with partial knife incision or "ab externo" incision. The corneal thickness was measured with a Haag-Streit pachometer prior to cataract extraction and 4 days to 6 months after the operation. The investigation showed that the postoperative increase of the corneal thickness returns as before the operation.

Cataract Extraction↗
PubMed1977

Retinal detachment treated by argon laser photocoagulation.

Argon laser photocoagulation was applied 2-3 weeks after implantation of episcleral silicone sponges as a second-step operation in 130 cases of retinal detachment. The chorioretinal scar for the occlusion of the tears was obtained exclusively with this procedure. Argon Laser used in cases with pronounced retinal elevation, i.e. where cryoapplication had proved inadequate or where a choroidal or retinal hemorrhage could be expected following cryoapplication. The advantages and disadvantages of the technique are evaluated with respect to the experience with cryoapplication.

Argon↗
PubMed1977

[Treatment and follow-up of retinal tears associated with avulsed overlying retinal vessels (author's transl)].

The present clinical study is based on 17 cases of a specific clinical entity, which is characterised by a retinal break without retinal detachment, the tear being spanned by an avulsed patient retinal vessel invariably adjoining the operculum. The vessel was in the vitreous cavity and formed an arch above the break. All cases began with a sudden decrease or loss of visual acuity due to the rupture of the avulsed vessel and the occurrence of hemorrhages within the vitreous. These hemorrhages recurred in the course of the follow-up of the patients which lasted from 1-8 years. The recurrence of the bleeding was in most instances related to the mobility and the size of the vessel overlying the break. During treatment the cases were divided into two groups, group 1 comprising cases which were subjected only to light-coagulation, whereas in the cases of group 2 scleral buckling was performed in conjunction with cryopexy or light-coagulation. The comparatively best results were achieved in group 2. This condition is rare and amounted to only 1.5% of our total number of cases of retinal tears treated with light-coagulation during the last 8 years.

Aged↗
PubMed1977

Vitreous inflammatory reaction. Vitreous inflammation in rabbits, induced by saline, air, or sodium salt of hyaluronic acid.

Inflammation of the vitreous body of rabbits after the injection of normal saline, sterile air, or SSHA was studied over a period of 30 days. The course of the inflammation follows a definite pattern: it shows an exacerbation 24 h after injection, an abrupt regression 48 h after injection, a new peak on the 8th day and subsequently a gradual regression until the 30th day. Although the course of the inflammation is approximately the same for the three vitreous substitutes, the reaction they provoke varies in intensity. The inflammation is most intense after the injection of SSHA and mildest after saline injection, while the intensity of the reaction caused by air lies between the two. The reaction was assessed by measuring the number and types of vitreous cells and the changes in the percentual proportions of globulin and albumin in the vitreous body, as well as by ascertaining the alterations of the vitreous structure.

Air↗
PubMed1976

The third component of complement (C'3) level in patients with uveitis.

In 23 cases of endogenous uveitis the third component of the complement (C'3) system was determined by the immunodiffusion method. No statistical difference was found in uveitis patients as a whole in comparison with the normal controls; although a rather high value of C'3 was found in six cases of Eales' disease and in three cases of Behçet's disease. The significance of these results is discussed.

Adolescent↗
PubMed1976

[Irvine-Gass syndrome. Statistical and angiographic study].

This study is based on a detailed investigation of 12 cases of Irvine-Gass syndrome which was observed during the examination of 350 patients operated for pathological or senile cataract. The authors have found that: Males were affected more than females. Arteriol hypertension increases the frequency of the disease. The syndrome was found at an increase frequency in cases of nuclear cataract and in case where cataract was extracted by cryo-extraction. The bulge of the vitreous within the anterior chamber (without rupture of the anterior hyaloid membrane) causes a higher frequency of the disease. A similar observation was made when there was an incarceration of the vitreous to the surgical wound. The retreat of the edema was faster when the syndrome appeared earlier than the cataract operation. Whereas the restoration of good visual acuity did not depend upon the time of appearance of the disease. During the fluorescein study the following was observed. The possible participation of the chorio-capillaris layer in the pathogenicity of the disease. The diffusion of the fluorescein diminished with the improvement of the disease. Fluorescein angiography is unquestionably superior to simple ophthalmoscopy or the coloured photograph of the fundus of the eye, because the full extent of the existing damage can be revealed only through this method.

Cataract Extraction↗
PubMed1976

[A new argon-laser-approach for the management of aphakic pupillary block (author's transl)].

9 cases of aphakic pupillary block with high intraocular pressure were managed successfully by means of a new argon-laser-technique. This new approach consisted in the application at the iris border, 1.5 mm from the pupillary border, of a mobile argon-laser beam of variable intensity, ranging from 250 to 500 mw, of constant time (0.5 sec) and of fixed spot size (200 mu). In some instances the beam was moved parallel and in other cases vertically to the pupillary border in the direction towards the ciliary portion of the iris. This technique ensures maximum retraction of the pupillary border, corresponding to the line of running application, coupled with the least possible damage to the iris and a minimum of applications. Simultaneously with the retraction of the pupillary border the posterior synechiae of the iris are detached and the out-flow of the aqueous trapped in the posterior chamber is released.

Cataract Extraction↗
PubMed1976

[Experimental hypertony caused by obstruction of the anterior chamber angle ab interno (author's transl)].

In 30 rabbits, separated into 3 groups (A, B and C), the entire area (A), three quarters (B) half of the anterior chamber angle (C) was experimentally obstructed by means of a homologous scleral graft. In groups A and B a statistically significant change of the intraocular pressure and of the cornea diameter was shown as compared with the control eye and group C. This change is due to the obstructed area of the angle. The increased intraocular pressure lasted for some months. The graft was well tolerated by the tissue of the angle and the obstruction of the angle was total, as was confirmed by means of the histological preparations.

Animals↗
PubMed1975

Extraocular observations in episcleral sponge implants.

The follow-up of 262 cases of retinal detachment operated on after the Custodis-Lincoff method in combination with cryopexy permitted the following observations: (1) The implant protruded in a number of cases under an intact conjunctiva and Tenon's capsule without discomfort to the patient. This protrusion depended mainly on the size and the manner of fixation of the implant, the distance of the point of fixation from the limbus and the condition of the conjunctiva. (2) Changes were observed in the conjunctiva in the fixation area, such as subconjunctival haemorrhage, cystoid degeneration of the conjunctiva and rupture with extrusion of the sponge. Subconjunctival haemorrhages were observed in 3.4% of the cases and were either absorbed or led to an inflammation. Cystoid degenerations occurred in 2.2% of our cases. These were limited to the edge of the sponge proximate to the limbus and involved only cases of radial fixation. Rupture of the conjuctiva and extrusion were noticed in 3.4% of the cases. (3) An inflammation due to the sponge was observed in 4.1% of the cases. Its time of onset varied between 3 days and 22 months. According to the time of onset the patients were divided into three groups. The gravity of the inflammation was proportionate to the earliness of the time of onset. Predisposing factors for the above complications were mentioned and discussed.

Conjunctiva↗
PubMed1975

[Some clinical aspects concerning diplopia after retinal detachment surgery with cryopexy and episcleral silastic sponge (author's transl)].

The aetiology of diplopia following retinal detachment surgery after the Lincoff-Custodis method is examined. Of 140 patients operated, 16 (i.e. 11.4%) developed diplopia. The authors believe that this diplopia is due to a fixation of the eyeball at the point of the silastic sponge placement. As responsible factors, which depend on the manner of sponge fixation and the size of the sponge, they regard: Alteration of the bulb curvature, shortening of the Tenon's capsule placed over the sponge, and changes in the conditions of muscular action.

Adolescent↗