Search PubMed⌕ Search

Biomedical subjects

G Rizzoni

Publications and source records attributed to G Rizzoni.

At least 127 records · Page 7Linked to original sources
PubMed1984

Growth in children with chronic renal failure on conservative treatment.

Statural growth and its relationship with degree of renal insufficiency were studied in 42 children and 5 infants with chronic renal failure (CRF). Most of the children had a congenital disease or were already ill in the neonatal period. Average GFR was 34 ml/min/1.73 m2 at the beginning and 16 ml at the end of the follow-up period, which averaged 4.3 years (1 to 12 years). Most patients grew at a normal rate; only 3 out of 42 children (7%) and 3 out of 5 infants lost one standard deviation or more during the follow-up period. No correlation was found between the degree of GFR and growth velocity. Catch-up growth was observed only for a 12-month period in 4 children with a bone age of 7 to 8 years. In 10 out of 11 children who reached puberty while under observation, a normal pubertal growth spurt was observed. Suitable and comprehensive controls and treatment can arrest growth retardation in the great majority of children with CRF after the first few years of life, regardless of their GFR. Achievement of a normal growth pattern in infants with CRF during the first year(s) of life remains a major unsolved problem.

Adolescent↗
PubMed1984

Cyanotic crises in a breast-fed infant from mother taking dipyrone.

Cyanotic crises occurred in a breast-fed infant whose mother was under treatment with dipyrone for a sore throat. No abnormalities were found at physical and routine laboratory examinations. Dipyrone concentrations in mother's serum and milk and in infant's serum and urine were 3.3, 4.3 and 3.2, 3.74 micrograms/ml respectively. It is concluded that the adverse effect could be due to dipyrone ingested with mother's milk.

Adult↗
PubMed1984

Electron microscopy for measurement of glomerular basement membrane width in children with benign familial hematuria.

Glomerular basement membrane (GBM) width was measured in 13 children with benign familial hematuria (BFH) and in 13 controls (6 children and 7 adults), using a standardized procedure and examining 3 glomeruli in each case. GBM widths were evaluated by comparing arithmetic means and considering the frequency of segments with a thickness less than 150 and 200 nm. With the former method, only 6 children with BFH fell below the normal values, while with the latter, 9 out of 13 were below the normal range. When BFH is suspected, it appears that GBM width is best evaluated by considering only the thinner segments, because the arithmetic mean can be influenced by the presence of thick segments and therefore has less diagnostic value.

Adult↗
PubMed1983

Evaluation of glomerular and nonglomerular hematuria by phase-contrast microscopy.

Glomerular and nonglomerular origins of hematuria may be identified by assessment of the shape and size of the excreted red blood cells. We examined 380 urine specimens from 179 children with hematuria (greater than or equal to 3500 RBC/minute) with phase-contrast microscopy. In 106 cases, the cause was known; the results agreed with the clinical, histologic, and laboratory diagnosis in 63 of 65 subjects (97%) with glomerulopathies and in 39 of 41 (95%) with nonglomerular hematuria. Casts were found in 54% of the specimens from the children with definite glomerular hematuria. Phase-contrast microscopic examination of red blood cells in the urine is a simple, inexpensive, and noninvasive technique that permits an accurate distinction between glomerular and nonglomerular bleeding in pediatric patients.

Adolescent↗
PubMed1982

Deciding to live.

The decision to begin chronic hemodialysis and, therefore, to fight for survival, creates an alliance between patient, family members, and medical staff. This alliance, which evolves by passing through various phases, becomes a central point in the difficult process which should permit the gradual achievement of independence. An example of this may be seen in the history of a young man of 21, who underwent a kidney transplant seven years ago. Analyzed in this article are certain moments of this case history, particularly the choice of treatment and the meaning of the word "choise" in this reality.

Adolescent↗
PubMed1982

Familial hypoplastic glomerulocystic kidney. A new entity?

Two pairs of female siblings of French and Italian origin presented with the histological picture of glomerulocystic kidneys. The cases differ from the patients previously described with glomerulocystic kidneys by the absence of major extrarenal malformations, the reduction of kidney size with absence of renal papillae and by the presence of stable chronic renal failure, starting during the first months of life. Both mothers of the patients also had chronic renal failure with similar urographic abnormalities.

Biopsy↗
PubMed1981

Cystinuria in children.

7 children, 20 months to 11 years old, with cystinuria and renal calculi were studied. Surgical treatment and alpha-mercaptopropionylglycine (MPG) gave satisfactory results in 5 children. The causes of the recurrences in the other 2 children are discussed. MPG therapy is effective but can cause a nephrotic syndrome at a dose of more than 50 mg/kg/day. A cystinuria of less than 200 mg/day cannot always be considered safe in children. The alkalinization and dilution of urine remain extremely important in the treatment of cystinuria.

Amino Acids, Sulfur↗
PubMed1980

Renal transplantation in children less than 5 years of age.

19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors was 26 +/- 11%. 10 children are currently surviving with functioning allographs (7 cadavers and 3 live relatives); 4 have died and 5 are undergoing dialysis after the loss of at least one allograft. Despite the poor allograft survival rate the fact that 7 children are surviving with cadaver allografts indicates that the lack of a living related donor should not prevent transplants in young children.

Adolescent↗
PubMed1979

Nephrotic syndrome during treatment with alpha-mercaptopropionylglycine.

We report 2 cases of cystinuria in which a nephrotic syndrome developed during treatment with alpha-mercaptopropionylglycine. This syndrome resolved after withdrawal of the drug and it did not recur when the alpha-mercaptopropionylglycine was given again in lower doses. The hypothesis is made that the nephrotic syndrome was dose-related. The alpha-mercaptopropionylglycine must be used in doses less than 50 mg./kg per day with regular monitoring of 24-hour urinary protein in cystinuric children.

Amino Acids, Sulfur↗