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PubMed · 7202450

Cystinuria in children.

L Pavanello·G Rizzoni·N Dussini·G Zacchello·G Passerini·A Tasca·F Pagano
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Abstract

7 children, 20 months to 11 years old, with cystinuria and renal calculi were studied. Surgical treatment and alpha-mercaptopropionylglycine (MPG) gave satisfactory results in 5 children. The causes of the recurrences in the other 2 children are discussed. MPG therapy is effective but can cause a nephrotic syndrome at a dose of more than 50 mg/kg/day. A cystinuria of less than 200 mg/day cannot always be considered safe in children. The alkalinization and dilution of urine remain extremely important in the treatment of cystinuria.

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Amino Acids, SulfurChildChild, PreschoolCystinuriaFemaleHumansInfantKidney CalculiMaleNephrotic SyndromeRecurrenceTioproninJournal Article

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L Pavanello, G Rizzoni, N Dussini, G Zacchello, G Passerini, A Tasca, F Pagano. 1981. Cystinuria in children.. https://doi.org/10.1159/000473204

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