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G Moulin

Publications and source records attributed to G Moulin.

At least 145 records · Page 8Linked to original sources
PubMed1990

[Erosive adenomatosis of the nipple. Report of 10 cases with immunohistochemistry].

Erosive adenomatosis of the nipple (also called florid papillomatosis of the nipple ducts) is an uncommon disease since only 358 cases have been published. We observed 10 cases in 10 years, corresponding to 1 case in 8,500 skin biopsies. One of these cases concerned a male patient and is the 13th of this kind in the literature. In our series the mean duration of symptoms was 15 months, as against 25 months in the 121 published cases where duration was clearly specified. In 8 of our 10 cases the patients consulted for oozing erosion or discharge of the nipple. Physical examination showed a palpable nodule in 2 cases, a small pediculate tumour in 1 case and nipple enlargement in 50 p. 100 of the cases. The patients were followed up for as much as 7 years. The outcome was always favourable. Recurrence was observed in only one patient, 7 months after limited excision; 6 years after a second excision no relapse was noted. Histological examination showed a papillomatous lesion in 5 cases, an adenomatous lesion in 2 cases and a mixed lesion in 3 cases. Myoepithelial cells were found in all cases, but they were doubtful or discreet in 4 cases. The apical pole of columnar cells was labelled by the ACE antibody, but labelling was very weak and partial in 4 cases. The columnar cell cytoplasm was constantly and strongly labelled by the KL1 anti-keratin antibody. The apical pole of parietal cells was strongly labelled by the antiepithelial membrane antigen antibody (EMA) in all cases.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenoma↗
PubMed1990

[Uterine cervix cancers: staging by magnetic resonance imaging].

The accuracy of Magnetic Resonance Imaging in cervical carcinoma staging for clinical stages superior to IB was studied retrospectively in 27 patients. The MRI results were then correlated with operative findings in 12 cases and with examination carried out under general anesthesia in 15 cases for myometrial, bladder, rectal, parametrial, parietal and vaginal extension. The accuracy of MRI was 81.5% for bladder, 92.5% for rectal, 87% for parametrial and 73% for vaginal extension. The accuracy of staging by MRI was 59%. The contribution of MRI in pre-operative studies for cervical carcinomas has not been properly defined until now. Nevertheless it is a particularly valuable technique due to its non invasive nature.

Adult↗
PubMed1990

[Wegener's granulomatosis. Contribution of computed tomography and nuclear magnetic imaging].

Amongst the endothoracic forms of Wegener's granulomatosis, tracheal, bronchial and above all mediastinal localisations are unusual. Such a case having a bad outcome is reported here. Computed Tomography (TDM) was used to assess the extend of pulmonary parenchymal involvement. Magnetic Resonance Imaging (MRI) was superior to TDM for showing transmural infiltration of the tracheal and the origin of main bronchi.

Bronchial Diseases↗
PubMed1989

[Diagnosis of gynecologic diseases].

Transabdominal ultrasonography has long been a fist-line examination to explore most of the pelvic diseases. Transvaginal sonography is a simple procedure giving an accurate and reliable diagnosis. These two techniques complement each other and can usefully be performed concomitantly. Computed tomography should be reserved to the extension assessment and follow-up uterine and ovarian tumours. Magnetic resonance imaging is a non invasive technique providing for a three-dimensional, very high quality study of the female pelvis. Its main value resides in the exploration of gynaecological tumours, where it gives a reliable assessment of local and regional extension. These various imaging techniques, therefore, have a definite, non competitive role to play in the exploration of gynaecological diseases. They are the necessary complements of physical examination and endoscopic methods.

Female↗
PubMed1989

Alpha2-adrenergic receptors in rat and rabbit eye: a tritium-sensitive film autoradiography.

Using a tritium-sensitive film and [3H]-clonidine, alpha 2-adrenergic receptors were localized in entire eye sections of rabbits and rats. This radioactive agonist specifically labelled three structures in albino animals: ocular muscles, ciliary processes and retina. In pigmented animals, uvea with melanin was intensively but nonspecifically labelled. Microscopic analysis of autoradiograms obtained with iris-ciliary bodies, revealed that the major localization of binding sites was in the ciliary process epithelium. In displacement studies, [3H]-clonidine binding was inhibited by alpha 2-adrenergic compounds while alpha 1- or beta-selective drugs had no inhibitory effects.

Adrenergic alpha-Agonists↗
PubMed1988

[Erysipelas].

Explore the source record for details and available documents.

Erysipelas↗
PubMed1988

[Familial primary disseminated amyloidosis (a new clinical form?)].

This report concerns two siblings we observed, one male the other female, who presented with primary disseminated amyloidosis. Repeated blood and urine examinations failed to demonstrate dysglobulinaemia. The brother developed, at the age of 51, extensive cutaneous amyloidosis with xanthochromia of the entire upper part of his body. His dermis contained a potassium permanganate-resistant amyloid substance. One year later, he presented with amyloid cardiomyopathy confirmed by biopsy. Owing to the intractable cardiac failure, heart transplantation was performed, but the patient died post-operatively. At autopsy, amyloid deposits were found to be present in the heart, liver, spleen and adrenal glands. His sister developed, at the age of 40, cutaneous amyloidosis in the form of yellowish and purpuric papules and plaques disseminated over the upper part of her body. Histological examination and electron microscopy of the skin showed large potassium permanganate-resistant amyloid deposits. In addition, endoscopy and histology demonstrated the presence of amyloid substance deposits in her larynx, oesophagus and rectum. Echocardiography revealed amyloid cardiomyopathy. She now has moderate cardiac failure, and heart transplantation is being contemplated. Like her brother, she has no renal of neurological amyloid lesions. There is no abnormality of serum or urinary globulins, and her SAA protein is present in normal concentrations. These cases do not fit in with the known nosological framework of amyloidosis. Clinically, both patients had disseminated amyloidosis of the AL type, and their disease clearly differed from familial systemic amyloidosis with neuropathy or nephropathy. To our knowledge, no case of familial primary amyloidosis of the AL type without dysglobulinaemia has yet been reported.

Amyloidosis↗
PubMed1987

Isolation and characterization of a mutant of Schwanniomyces castellii with altered respiration.

We have tried to isolate respiratory deficient mutants of the amylolytic yeast Schwanniomyces castellii CBS 2863 after mutagenesis with acriflavine. One of the mutants called DR 12 has been studied in more detail. Pasteur effect present in the wild-type is lost in the mutant, on the contrast an obvious Crabtree effect was observed: fermentation was almost as active in aerobiosis as in anaerobiosis. Moreover, the rate of anaerobic fermentation of the mutant was almost twice that of the wild type. This mutant was cytochrome b-deficient while the amount of the other cytochromes was larger than in the wild-type. Moreover, the level of these remaining cytochromes in the mutant was higher on non-repressive medium than on glucose medium. However, the fact that the mutant DR 12 retained a cyanide-sensitive respiration and that it was able to grow on ethanol as a non-fermentable substrate is noteworthy.

Acriflavine↗