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Biomedical subjects

G Hansson

Publications and source records attributed to G Hansson.

At least 127 records · Page 7Linked to original sources
PubMed1977

Duplication of the renal pelvis and blind-ending bifid ureter in twins.

Blind-ending bifid ureter in a woman with urinary tract infection and a duplicated renal pelvis in her twin sister are reported. The blind-ending bifid ureter terminated as a fibrous cord with a terminal mass of immature renal tissue. This type of ureter may be a transitional form between histologically blind-ending bifid ureter and duplication of the renal pelvis and/or kidneys. Findings in twins support this opinion.

Adult↗
PubMed1977

The effect of impact loading on rabbit knee joints.

Eighteen mature male Whiteland rabbits received repetitive impulse loads slightly larger than body weight (4 kp) through one knee joint for periods from 1 to 6 weeks. Mechanical compression of subchondral bone cores from impacted tibiae showed progressive increased deformation under a constant force. Cartilage degeneration occurred concurrently with alterations in the mechanical properties of the subchondral bone. The cartilage degeneration may be explained by: (i) the deleterious effect of repetitive mechanical compression, (ii) the decreased mechanical support of the underlying subchondral bone.

Animals↗
PubMed1976

Condyloma acuminatum of the bladder.

Condyloma acuminatum in the bladder of 2 patients on immunosuppressive therapy after kidney transplantation is described. The successful treatment was transurethral electroresection and coagulation. We do not recommend radical operations in cases of condyloma acuminatum. Resected specimens should be examined pathologically to exclude papillary epithelial tumors.

Adult↗
PubMed1976

Evaluation of the pain suppressive effect of different frequencies of peripheral electrical stimulation in chronic pain conditions.

The pain suppressive effect of low (2/s) and high (50-100/s) frequency electrical stimulation was studied in 12 patients with severe chronic pain in the back and/or the legs. All patients were subjected to a thorough physical examination before and 2-3 weeks after a series of stimulation sessions. The stimulation was applied via surface electrodes to areas both segmentally related and segmentally unrelated to the regions of chronic pain. Low frequency stimulation induced a partial pain relief in only one patient whereas stimulation with high frequency gave a suppression of pain in seven patients. The effect was short-lasting in most cases and the pain started to increase usually within 30 min. It is concluded that the observed pain suppression is not due to psychological factors but to more basic neurophysiological mechanisms. Augmentation of the effect after repeated stimulation sessions was not observed, neither was there any alteration in the neuro-orthopedic status nor any lasting pain relief in any patient.

Adult↗
PubMed1976

Effect of chemical modifications on the metabolic transformation of prostaglandins.

The metabolism of three analogues of PGF2alpha was studied in the Cynomolgus monkey and in the human, viz., 15-methyl-PGF2alpha, 16,16-dimethyl PGF2alpha, and 17-phenyl-18,19,20-trinor-PGF2alpha. The half-lives of the three compounds in the human circulation was considerably longer than that of PGF2alpha. The dehydrogenation of the secondary alcohol group at C-15 was completely blocked in the two first-mentioned compounds. These were degraded mainly by beta-oxidation, and their main metabolites, both in plasma and urine, were dinor-15-methyl-PGF2alpha and dinor-16,16-dimethyl-PFG2alpha, respectively. 17-Phenyl-18,19,20-trinor-PGF2alpha, finally, was metabolized to some extent by dehydrogenation at C-15, and also by reduction of the delta13 double bond and by beta-oxidation.

Animals↗