Biomedical subjects
Publications and source records attributed to G Cennamo.
The authors, after reviewing the literature, particularly the classification of optic nerve-head abnormalities, describe several clinical cases dealing especially with the notable diagnostic possibilities of ultrasound examination.
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Standardized A scan echography is the best technique for the biometric parameters of the eye. This has been very useful in studying the sizes of the anterior and posterior segments of the eye in hereditary microphthalmos. Echography and a genetic study led to a new classification of hereditary microphthalmos.
Attempt to retard growth of the eye in 4 young rabbits by means of prolonged ocular hypotony maintained by timolol-maleate were not successful. The eyes treated with 0.5 timolol twice a day showed a sustained hypotensive response of 4-5 mm Hg which lasted for the 4 months experimental period. No significant differences in size and on rate of growth in the treated and the untreated eyes were noted. In fact, over the 4 months postnatal period, both groups of eyes increased 0.5 mm per week in axial length. Our experiment suggests that in developing rabbit eyes, at least reduction of IOP is not a factor in effecting a smaller globe.
A patient with a juxtapapillary hamartoma is described, in consideration not only for the scarcity of such cases described in the literature, but also for the clinical and echographic characteristics that were observed for the involvement of the right eye, and because the patient was female. Echography and especially standardized A-scan echography, showing a lesion at high reflectivity without acoustic shadowing, allowed us to exclude the presence of a malignant melanoma and retinoblastoma, and directing us to the diagnosis of a malformation of angiomatous type.
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43 clinically euthyroid patients with unilateral exophthalmos were examined using clinical methods, echography, and computerized tomography. The functioning of the hypothalamic-hypophyseal-thyroid axis was investigated by measurements of TSH (before and after stimulation with TRH), thyroid hormones and antithyroglobulin antibodies. After a review of the literature, the results are discussed.
A case of bilateral multiple pigment epithelium detachments in a 36 year old man is reported. The value of E.R.G., E.O.G. and fluorescein angiography in the differential diagnosis between multiple serous detachments of the pigment epithelium and multiple vitelliform degeneration is stressed.
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The standard X-ray preserves its value in verifying the presence of a foreign body (FB). The echography is valuable in verifying the site of a FB when it remains uncertain in respect to the sclera after X-ray localization. Computerized tomography scanning offers useful information about the physical nature of the FB.
The authors report a case of posterior dislocation of the lens during the natural history of a clinical case of herpes zoster. An echographic B-scan study was carried out to reveal the position and the size and the shape of dislocated lens, together with its structure and that of ocular media. After a discussion on the possible aetiology of the lens dislocation it was considered due to herpes zoster disease, and are reported the possible mechanism of zonula alteration.
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