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Biomedical subjects

G Belloni

Publications and source records attributed to G Belloni.

At least 91 records · Page 5Linked to original sources
PubMed1971

Epidemiological study of long-term effects of pesticides on human health.

Two rural areas in Italy with different rates of pesticide usage were subjected to a cross-sectional investigation, based on the identification of organochlorine compounds in the environment and in human fatty tissues and on the determination of their concentration and a prospective investigation, based on the collection of data of past and present pathology and symptomatology from two stratified random groups of inhabitants of both areas.The cross-sectional investigation showed only small differences in environmental pollution and no differences in the storage of organochlorine compounds in fatty tissues in the two areas. The prospective investigation showed a higher prevalence of pathology and symptomatology in the population of the area where pesticides were used in larger quantities. Several haematochemical tests were used in an attempt to differentiate between populations at different levels of risk of toxic damage, but without success.

Adolescent↗
PubMedDate not supplied

Pituitary microadenomas in children: a cause of growth failure.

Six children, originally regarded as being affected by prepubertal idiopathic growth failure, were found to have pituitary microadenomas. In all six patients, the growth failure (less than or equal to 2 cm/yr) was the primary clinical sign, and was accompanied by a growth hormone deficiency that was discovered during the laboratory evaluation. Prominent alteration of the sella turcica was not demonstrated in the skull x-ray examinations of any of the children, even when the x-ray examinations were supplemented by hypocycloidal tomography. CT scanning proved to be a very useful integrating diagnostic procedure, revealing the adenoma to be a nodular area of increased density within the sella turcica. In all of the children, resumption of normal growth was obtained following the surgical removal of the tumor through a transsphenoidal approach.

Adenoma↗
PubMedDate not supplied

Measuring complexity/level of care and appropriateness of resource use in intensive care units.

BACKGROUND: Throughout the world, the cost of critical care medicine is increasing more than the overall health care cost. Thus, a higher attention to improve the efficiency of the use of ICU resources is indispensable. The objective of this study was the development of a simple and reliable tool for the evaluation of the appropriateness of ICU utilization. METHODS DESIGN: A repeated cross-sectional data collection was performed twice a week, during a 61-day study period. SETTING: Twenty-three Italian general ICUs. PATIENTS: All patients present in the 23 ICUs on the 17 index days. INTERVENTIONS: On each index day, patients were checked for receiving ventilation/CPAP, pulmonary arterial pressure monitoring, intracranial pressure monitoring, vaso-active drug infusion and hemodialysis-ultrafiltration. Simultaneously, each ICU bed was assessed for its technical and personnel facilities in order to estimate the deliverable level of care. RESULTS: A total of 1250 patients were studied, for a total number of 7533 patient-days. The overall occupancy rate per ICU was 83.8% (-range: 54.4% to 96.1%). The high-level occupancy rate (rate of patients requiring high level of care and actually occupying high-facility beds) was 69.4% (range: 25.0% to 149.0%), while the corresponding low-level occupancy rate was 101.1% (range: 31.3% to 329.4%). CONCLUSIONS: Our model clearly showed up a certain degree of inappropriateness in the use of ICU resources. Most of the ICUs (69.6%) used a very large proportion of their high-facility beds for patients who did not need high-level care. Being very simple, our method could represent a useful tool for continuous evaluation of the appropriateness of resource utilization in the ICU.

Aged↗