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Biomedical subjects

G Belloni

Publications and source records attributed to G Belloni.

105 records · Page 6Linked to original sources

A randomised, double-blind, vehicle-controlled study to evaluate the efficacy and safety of MAS063D (Atopiclair) in the treatment of mild to moderate atopic dermatitis.

MAS063D (Atopiclair is a hydrolipidic cream that has been developed for the management of atopic dermatitis (AD). The putative active ingredients of MAS063D are hyaluronic acid, telmesteine, Vitis vinifera, glycyrrhetinic acid. A five-week study in 30 adult patients with mild to moderate AD showed that MAS063D offered significant benefits over a vehicle-only control. MAS063D improved the total body area affected (17.2% --> 13.2%, p < 0.001), itch score (2.7 --> 1.3 on a 10-point scale, p = 0.001) and EASI score (28.3 --> 24.3, p = 0.024) after 22 days treatment compared to baseline. The patients' opinion of MAS063D (patient's view of itch control, and view of study substance) was rated by participating patients as significantly better than control (p = 0.008, p = 0.042 respectively). Based on these preliminary results in a small scale study, it is suggested that MAS063D is a possible new treatment option for improving signs and symptoms in adults with mild to moderate AD.

Adolescent↗

[Primary biliary cirrhosis with onset in pregnancy: a case report].

A case of primary biliary cirrhosis occurred during the first quarter of pregnancy in a 29-years-old primipara is described. Possible relationships with a former anti-hepatitis B vaccination and with positive familiarity reduction of IgA are discussed. Follow-up to the patient after two years therapy with colchicine 1 mg a day is also described.

Adult↗

[Survey of childhood handicaps in the Unità Sanitaria Locale No. 22 "Valtiberina"].

An epidemiological research about the infantile handicaps has been carried out to make a quantitative and etiological valuation of the existing cases in the social, economic and cultural sphere of U.S.L. number 22 "Valtiberina". Considering an infantile population of 5,063 subjects, 55 cases, corresponding to 1.08% have been examined; 32 of them are male children and 23 are female children. The research which has been carried out shows that there are more cases of psychological handicaps (35 cases out of 55) rather than of organic handicaps. It seems that it is possible to find a connection between this high percentage and the social, economic and cultural situation of the territory. At the same time an efficacious work has been carried out by the Social and Medical Services of U.S.L. and by the school to recognise, to point out, to diagnose and to study these pathologies. Such a study can result useful if we want to plan a campaign to prevent and to treat as soon as possible the infantile handicaps.

Adolescent↗

[The portal hypertension syndrome. Limitations of medical treatment and prevention of complications].

The aetiopathogenesis of portal hypertension and the hepatic and renal haemodynamics involved in the syndrome are reviewed. Medical treatment possibilities are then considered in the light of the mechanisms underlying the condition. Modalities of diuretic treatment and the possibilities of controlling it in order to prevent the onset of a hepato-renal syndrome are discussed, particular attention being paid to the role of volaemia.

Antihypertensive Agents↗

Iopamidol and metrizamide in cervical myelography: side effects, EEG, and CSF changes.

Two nonionic contrast media, iopamidol and metrizamide (Amipaque), were used for cervical myelography (C1-C2 puncture) in 95 consecutive patients. Both contrast media gave excellent radiographic results. Headache and vagal symptoms were similar in both groups, whereas metrizamide produced more electroencephalographic changes and epileptic seizures. Meningeal irritation occurred in both groups and was severe in three cases. Cerebrospinal fluid showed protein and cellular changes of inflammatory type in both groups. Iopamidol is considered to be the more suitable contrast medium for cervical myelography despite its slight neurotoxicity.

Cerebrospinal Fluid↗