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Biomedical subjects

G Anneroth

Publications and source records attributed to G Anneroth.

At least 55 records · Page 3Linked to original sources
PubMed1987

Glass-ionomer cement as retrograde filling material. An experimental investigation in monkeys.

The tissue reaction following the use of glass-ionomer and amalgam, as retrograde filling materials was investigated in an experimental study using 8 monkeys. After apicectomy of the upper central incisors, amalgam and glass-ionomer cement was used at random as retrograde filling material. 2 animals at a time were sacrificed after 2 weeks, 1, 3 and 6 months. Irrespective of the length of time, the tissue reactions were similar for the 2 materials. 2 weeks after surgery, a vascular granulation tissue containing lymphocytes, plasma cells and polymorpho-nucleated leukocytes was observed close to the retrograde fillings. 1 month after surgery, good healing was found, the granulation tissue being replaced by new osteoid or bone formation. After 3 and 6 months, there was complete healing with no inflammatory reaction and a mature alveolar bone surrounding the apicectomized roots.

Animals↗
PubMed1987

Review of the literature and a recommended system of malignancy grading in oral squamous cell carcinomas.

A review of histologic classification systems for grading of malignancy in squamous cell carcinomas of the head and neck region is presented. Reasons behind the varying results obtained in studies using histomorphologic grading schemes are presented and potential errors involved in this type of clinical research are discussed. Requirements for the study of correlations between malignancy grade scoring, and recurrence and survival rates are presented. These include factors as patient selection, clinical staging, and follow-up principles. Special attention must be given to treatment modalities, establishment of negative surgical margins and occurrence of regional lymph node and/or distant metastases.

Carcinoma, Squamous Cell↗
PubMed1986

Acquired immune deficiency syndrome (AIDS) in the United States in 1986: etiology, epidemiology, clinical manifestations, and dental implications.

The acquired immune deficiency syndrome (AIDS) results from a lymphotropic retrovirus (HTLV-III) infection and is characterized by specific opportunistic infections and malignancies. The virus is transmitted primarily by semen and blood. Infection is limited principally to defined risk groups, i.e., homosexual men and intravenous drug users. Head and neck manifestations include cervical lymphadenopathy and Kaposi's sarcoma. Oral manifestations include Kaposi's sarcoma, candidiasis, hairy leukoplakia, precocious periodontal disease, xerostomia, herpes simplex, recurrent aphthae, erythema multiforme, and venereal warts. Although HTLV-III is present in saliva, there are no reported cases of transmission secondary to dental procedures. Appropriate precautions and techniques are recommended in treating patients at risk for AIDS.

Acquired Immunodeficiency Syndrome↗
PubMed1986

Nasopalatine duct cyst.

A retrospective and follow-up study of 35 cases of nasopalatine cysts was performed. The retrospective part of the investigation comprised clinical, radiological and histological observations including pre-, intra- and post-operative findings. The follow-up included clinical and radiological observations. The results indicated that most cysts are found during routine clinical and radiological examination. Subjective and objective clinical symptoms were reported in 50% and 59% of the cases, respectively, the most common being swelling and pain. It was not possible to confirm any specific etiological factor. In 97% of the cases, maximum cyst diameter varied between 1.0-2.5 cm and 84% appeared round or ovoid. Histological examination revealed a high frequency of cuboidal and/or columnar epithelial lining, 2-3 cell layers thick, in combination with an adjacent zone of hyalinized capsular tissue with low-grade inflammation. Radiologically these cases exhibited a well-defined cortical border. In the follow-up study, 84% of the patients exhibited complete clinical healing with no objective or subjective symptoms. Complete bone regeneration was seen radiologically within 3 years in 82% of the cases examined. The results of the present study were compared to those obtained in previous reports.

Adult↗
PubMed1986

Malignancy grading in oral squamous cell carcinoma. I. Squamous cell carcinoma of the tongue and floor of mouth: histologic grading in the clinical evaluation.

In a retrospective histological and clinical study, a multifactorial grading system was used for histological classification and grading of malignancy in 51 cases of squamous cell carcinoma of the tongue and floor of mouth. The results indicated that the use of such a multifactorial grading system, consisting of 7 morphological parameters, including an evaluation of both the tumor cell population itself and the tumor-host relationship, can serve as an important supplement to clinical judgement in determining the outcome of the oral tumor.

Adult↗
PubMed1986

Malignancy grading of squamous cell carcinoma in the floor of the mouth related to clinical evaluation.

A multifactorial grading system was used for histologic classification and grading of malignancy in 89 patients with squamous cell carcinoma in the floor of the mouth. All patients had been treated with surgery alone and only those patients were included in the study who at the initial diagnosis had no clinically suspected regional lymph node or distant metastatic involvement. There was a statistically significant correlation between the mean total malignancy scoring, on the one hand, and clinical staging, frequency of recurrences, and death from the first primary oral carcinoma, on the other.

Carcinoma, Squamous Cell↗
PubMed1986

Necrotizing sialometaplasia--a malignancy simulating oral lesion.

A case of necrotizing sialometaplasia is reported in a 63-year-old white male. The lesion appeared as an ulcerated and painful lesion inside the left ramus mandibulae. An incisional biopsy was performed and reported as well-differentiated squamous cell carcinoma. A few days after the initial biopsy was taken the necrotizing tissue disappeared and the ulcer started to heal. A new, excisional biopsy was performed. The initial diagnosis was revised and the lesion reported as necrotizing sialometaplasia. Two weeks after the excisional biopsy complete healing was obtained. The clinical and histological findings are discussed in relation to the different stages through which a necrotizing sialometaplasia might develop. From a differential diagnostic point of view it is important for both the clinician and pathologist to be aware of the lesion's behaviour during the different stages of development.

Biopsy↗
PubMed1985

Endosseus titanium implants in extraction sockets. An experimental study in monkeys.

In a series of monkeys, titanium implants (Xenodent) were installed in the sockets of mandibular incisors. The animals were sacrificed 7 and 12 weeks after the implantations. The healing was studied by histological and microradiographical techniques. A gradual osseointegration free from adverse interference could be noticed.

Alveolar Process↗
PubMed1985

The effect of radiation on teeth. A clinical, histologic and microradiographic study.

54 teeth from 20 patients irradiated for treatment of malignant tumors of the head and neck region were examined clinically, histologically and microradiographically. 18 teeth from 8 patients were used as controls. A significantly higher degree of hyposialia, radiation mucositis and atypical caries was found in the original group as compared to the control material. Occurrence of narrow gaps between dentin and cementum was also higher in the former group as compared with the latter.

Adolescent↗
PubMed1985

Peripheral ameloblastoma.

Peripheral ameloblastoma is an extremely rare variant of a very well-known and aggressive odontogenic tumour. Only 16 cases have been reported so far. Because of the paucity of cases reported, this report written.

Adult↗
PubMed1985

Periodontal ligament injection. An experimental study in the monkey.

In an experimental double blind, cross-over study in monkeys, the reactions of the periodontal tissue after periodontal ligament injection of local anaesthetic solution were investigated. Lidocaine 20 mg/ml with adrenaline 12.5 micrograms/ml and mepivacaine 30 mg/ml were used, and the injection times were 5 or 20 s. Histopathological analysis showed cell damage in the tissues near the injection areas immediately after the experimental procedure. In the specimens obtained one week after the periodontal ligament injections, the tissues were found to be normal.

Alveolar Process↗
PubMed1984

A methodologic study of histologic classification and grading of malignancy in oral squamous cell carcinoma.

A multifactorial grading system was devised for the histologic classification and grading of malignancy in carcinoma of tongue and floor of mouth. The system is presented with all morphologic variables defined and illustrated. Statistical analysis of the classification of 52 cases of squamous cell carcinoma revealed that the reproducibility of the system by two independent observers was good for all morphologic variables. Mean total malignancy, tumor cell population, and tumor-host relationship scores showed statistically significant correlations with mean ratings for all the different morphologic parameters, with certain specified exceptions. Reasons for the exceptions and lack of correlation of the histotechnical and theoretical errors of previous grading systems are explored.

Biopsy↗
PubMed1983

Minor salivary gland calculi. A clinical and histopathological study of 49 cases.

The clinical and histopathological characteristics of 49 previously unpublished cases of sialolithiasis of minor salivary glands are presented. The lesions are usually solitary, small, submucosal nodules, which are hard or firm and freely movable in the surrounding tissue and on rare occasions may be multiple. They are most often seen in the buccal mucosa and the upper lip of patients in the 5th, 6th or 7th decade, but are rarely found in the lower lip and palate. The authors found that clinicians usually failed to include calculi in the differential diagnosis and further, they concluded that minor salivary gland calculi are more common than generally believed. In contrast to other studies of calculi in major and minor salivary glands, the periphery of the stones was found to be less frequently lamellated and mineralized. The authors also confirmed the finding of mucous cell metaplasia of ductal epithelium and commented on its possible role in the pathogenesis of sialolithiasis.

Adolescent↗
PubMed1983

An epidemiologic study of malignant oral tumors in Sweden 1958-77.

The paper presents epidemiologic data of malignant oral tumors in Sweden 1958-77 including the total number of cases, the number and relative frequency of cases in different sublocations of the oral region and the mean annual age standardized incidence rate, all ages, per one million population, by site and sex. An analysis of different histopathologic types of oral tumors is also presented. A comparison is made between the two 10-yr periods 1958-67 and 1968-77. Errors involved in epidemiologic studies are discussed.

Adolescent↗
PubMed1983

The snuff-induced lesion. A clinical and morphological study of a Swedish material.

Snuff-induced oral lesions were studied clinically, histologically and by electron microscopy. The material was collected from 21 male snuff users. The lesions had a characteristic whitish appearance with a wrinkled swollen texture and the most common localization was in the vestibular area of the upper jaw. In two cases gingival retraction was observed. The light-microscopical examination showed a mild epithelial dysplasia in five cases. No carcinoma in situ or invasive carcinoma was recognized. In some of the cases ultrastructural changes in the basement lamina region, such as defects of the basement lamina and the occurrence of basal cell processes in the connective tissue, were observed. Odland bodies were seen in the epithelium. In the connective tissue filamentous material of unknown nature was found. The ultrastructure of the filamentous material suggested that it might be amyloid. In summary, snuff-induced lesions should be diagnosed, patients should be informed and made to quit the habit, and remaining lesions should be followed up regularly.

Adult↗
PubMed1983

Hyperplastic lesions of the gingiva and alveolar mucosa. A study of 175 cases.

175 'epulides' were studied clinically and histologically. The lesions were histologically reclassified into three groups: granulomatous, fibromatous and giant cell lesions. The granulomatous group was four times and the giant cell group 1.5 times more frequent in females. It is suggested that the expression epulis should be abandoned as a microscopic designation for lesions in the oral mucosa, as it is only a non-specific topographico-clinical concept comprising histogenetically and histomorphologically differing lesions and therefore does not represent a uniform group. The suggested new terms for the three types of hyperplastic lesions are oral mucosal granulomatous hyperplasias (including such diagnostic terms as granulomatous gingivitis, gingivitis of pregnancy, granuloma gravidarium, pyogenic granuloma, epulis angiomatosa and epulis telangiectaticum), oral mucosal fibrous hyperplasias (including such diagnostic terms as fibrous epulis, epulis fissuratum, fibroepithelial lesions, denture injury tumor and peripheral odontogenic fibroma) and oral mucosal giant cell hyperplasia (including such diagnostic terms as peripheral giant cell granuloma and giant cell epulis).

Adolescent↗
PubMed1982

Variations in keratinizing odontogenic cysts and tumors.

Classification of keratinizing odontogenic cysts and tumors is not entirely satisfactory to the clinician and pathologist because many individual cases do not fit precisely into a particular category. This report describes the nature of some of these marginal lesions in order that similar cases may be diagnosed and treated correctly. Eight selected cases are described histologically, and their clinical behavior is discussed. It is concluded that the histopathologic appearance of the odontogenic epithelium in odontogenic cysts and tumors varies to a large extent and gives rise to a variety of keratinizing lesions. It is further concluded that some varieties are unique and, for the present, treatment of the rare lesions depends more on observed clinical behavior, with morphology having a lesser role in prognosis. It is important that clinicians as well as pathologists be aware of the wide variation of these keratinizing lesions so that the patient will receive optimum treatment.

Adult↗