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Biomedical subjects

G Anneroth

Publications and source records attributed to G Anneroth.

At least 73 records · Page 4Linked to original sources
PubMed1982

Oral condyloma accuminatum. A light and electron microscopic study.

In 2 cases with clinical and histopathological features of oral condyloma accuminatum, virus-like particles were identified both in the cell nuclei and the cell cytoplasm. We are concerned here with etiological factors and with differential diagnostic problems related to these extremely rare oral lesions.

Adult↗
PubMed1982

Eruption of maxillary canines.

In 79 of 124 children with bilaterally located widened follicles around non-erupted canines one of the maxillary canines was chosen by lot for surgical exposure of the tooth crown. In seven cases both maxillary canines were exposed. The remaining 38 children were radiographically controlled at certain time intervals as were the 86 cases where surgery was performed. The follicles removed from 52 cases were histologically examined. The result showed that surgical exposure did not enhance the eruption of the tooth. The histological examination showed that the histologic appearance of the extirpated follicle did not correspond to the radiographically verified width of the pericoronal space. The specimens were composed of a loosely arranged fibrous connective tissue with an epithelial lining occurring in 77% of the cases. The epithelial lining consisted of reduced enamel epithelium and showed in none of the cases squamous metaplasia or keratinization. Nor was there any clinical or histologic sign of a neoplastic or cystic change of the follicle.

Adolescent↗
PubMed1982

Oral leukoplakias. A microradiographic and lipid-histochemical study.

Biopsies from 13 oral leukoplakias and from normal tissue specimens in the contralateral region of each patient were examined microradiographically and lipid-histochemically using freeze-sectioned and freeze-dried sections. The investigation showed that an epithelial zone of cell layers with different degrees of keratinization and varying dry mass concentrations occurred in oral leukoplakias. A concentrated localization of phospholipids, free fatty acids and cholesterols was found in the zones with a high dry mass content and, consequently, high keratin content, while a negative lipid reaction was obtained in the zones where the dry mass concentration was low.

Adult↗
PubMed1981

Jaw cysts with special regard to keratocyst recurrence. A long-term follow-up.

From an original material of 50 patients with 55 jaw cysts, 39 patients were followed up 32--129 months after surgery (mean: 92 months). In 21 of 55 cysts the primary lesion was histologically classified as a keratocyst. All keratocysts had a follow-up period of at least 6 years (72 months). The keratocyst recurrence rate was 50%. Seven of eight recurrences in the total material were keratocysts. There was no difference between males and females concerning the incidence of keratocysts or age at diagnosis.

Adolescent↗
PubMed1980

Acanthomatous ameloblastoma.

A clinical, radiographic and histopathologic report is presented of a case of acanthomatous ameloblastoma in relation to a cystic lesion surrounding an impacted third molar in the left mandible of a 37-year-old healthy woman. The histological examination of the removed specimen revealed the histopathological pattern of an acanthomatous ameloblastoma. In the discussion a survey is presented of the literature concerning acanthomatous ameloblastoma. Special attention is thereby given to the question of malignancy. It is stated that the metaplastic transformation into squamous epithelium which occurs in acanthomatous ameloblastoma does not predispose to malignant changes, to increased recurrent rate or to more extensive invasion of the tumor.

Adult↗
PubMed1980

Unilateral odontodysplasia.

A case of malformation of five permanent teeth in the right maxilla is described. The asymmetrical malformations were probably caused by an early local trauma of the right maxilla. This trauma led to defective mineralization of the deciduous tooth germs, which was verified roentgenologically. The resulting early osteitic process caused injury to the permanent germs at a sensitive mineralization period. Mineralization disturbances of 13, 14, 15, 16 and 17 were established roentgenologically. In the other halves of the jaws the development was entirely normal. Endocrinological examination showed normal values and there were no signs of hypothyreosis or Turner's syndrome. Acute symptoms in the right maxilla at the age of 9 necessitated extraction of germs 14 and 16. As subsequent roentgenograms showed that 13 and 15 were not developing normally in respect of mineralization, these were extracted at, respectively, 12 and 13 years of age. For the same reason 17 was extracted two years later. The histopathological examination showed in all involved teeth a pronounced malformation with disturbances both of the morpho- and histodifferentiation of the various dental tissues.

Child↗
PubMed1978

Angiolithiasis in the parotid gland.

Angiolithiasis in salivary glands is a very rare finding, and the knowledge of the morphology and histogenesis of these stone formations is therefore limited. Six small angioliths from the left parotid gland of a 19-year-old girl were examined histologically, microradiographically and diffractometrically. The angiolithiasis developed from a regressed hemangioma which had been observed since the patient was 3--4 years old. The angioliths, which were encapsulated, exhibited in some areas diffuse laminations with shells of alternatingly high and low mineral content. In other areas, however, the sturcture of the stones was rather homogeneous. The central part of all angioliths was highly mineralized. All the examined specimens exhibited a mineral pattern of pure apatite. Due to presence of erythrocytes as well as of fibroblasts in the matrix of the examined noduli, the diagnosis of angiolithiasis was established.

Adolescent↗
PubMed1978

Syndrome of multiple mucosal neurofibromas, pheochromocytoma and medullary thryoid carcinoma. Report of a case.

The present article reports a case of multiple endocrine neoplasia (MEN) syndrome, type IIb, including the following components: pheochromocytoma, medullary thyroid carcinoma, hyperplastic corneal nerves and multiple mucosal oral and ocular neurofibromas. The patients, a 35-year-old male also exhibited a series of other pertinent findings, i.e. thickened eyelids, marfanoid habitus and widened mandibular canal and mental foramina. In the discussion the clinical and histopathologic characteristics of the present case are compared with similar findings in other previously published cases. The multiple oral mucosal neurofibromas are described clinically and histopathologically and are stated as a pathognomonic early sign of the syndrome.

Adult↗
PubMed1978

Clinical, histologic and micro-radiographic study of natal, neonatal and pre-erupted teeth.

A clinical, histologic and microradiographic investigation of 62 natal, neonatal and otherwise pre-erupted teeth from 51 children is presented. Such a comprehensive material has not previously been reviewed. Of the 62 teeth, 59 were mandibular incisors. A hereditary factor could be demonstrated in 12 cases. Fifty-three teeth showed more or less pronounced enamel hypoplasia. The enamel had a normal prism structure and mineralization with the exception of 22 cases where the prism structure was absent in the cervical part of the enamel. The cervical and apical dentin was atubular and in developing teeth the dentin in these regions changed to an irregularly formed hard tissue of osteodentin character, in which enclosed cells could be observed. Developing teeth often had no cementum, and in those cases where acellular cementum could be observed it was thinner than normal. In four patients atypically located carious lesions occurred.

Child↗
PubMed1978

Ultrastructure of salivary calculi.

Twenty-one submandibular salivary calculi from 19 patients were examined with the light and electron microscope. Adjacent to the peripheral parts of the calculi metaplastic squamous epithelium or connective tissue was seen in close contact to the mineralized matrix. Disintegrated cellular substances from these tissue components were in some cases found to condense in a peripherally located zone of the salivary calculi. The morphology of the examined salivary calculi varied extensively not only within each calculus but also from one calculus to another. High and low incidence of crystals gave rise to the lamellated pattern. In some cases the crystals were so abundant as to five a dense homogeneous appearance. In the central parts of the calculi spheroid bodies of very low electron density with a size ranging from 1 to 100micrometer were found in an amorphous matrix. The origin of these structures is discussed. In the peripheral parts of some calculi osmiophilic spherical bodies with an electron microscopical appearance similar to lipid granules as well as bacteria of cocci or coliform type were found. Degenerated bacteria might in some cases contribute in forming part of the peripheral organic matrix.

Humans↗
PubMed1977

The relation of lipids to the mineral components in salivary calculi.

Using lipid histochemical and microradiographic methods, the distribution of lipids and the inorganic component in different areas of salivary calculi was investigated. Two main groups of lipids were found, i.e. hydrophilic phospholipids and hydrophobic lipids. The hydrophilic phospholipids were shown to be composed mainly of phosphosphingosides and of the hydrophobic lipids cholesterol was demonstrated. Phosphosphingosides were localized in more or less lamellar zones as also in large homogeneous areas. In some cases the calculi were surrounded by a structureless non-mineralized zone exhibiting a strongly positive reaction for phosphosphingosides. Cholesterol was found in isolated band-formed areas. Phosphosphingosides and cholesterol were especially prevalent in areas showing a low or slight degree of mineralization. In areas showing a high degree of mineralization the corresponding lipids gave a weak or absent histochemical reaction. After EDTA-decalcification, however, an increase in the concentration of lipid was noticed in high mineralized areas, indicating a masking process. The influence of various factors on the presence and distribution of different lipids was discussed.

Autoradiography↗
PubMed1977

Lipidhistochemical and microradiographic study of distribution of lipids in relation to mineral content in dentin caries.

Fifteen human molars were investigated using lipidhistochemical and microradiographic methods. A peripheral necrotic and totally decalcified part of the carious lesion revealed a markedly positive staining reaction for sphingomyelin, sulfatides, cholesterol- and/or triglyceride-esters. The reaction was probably conditioned by the presence of debris and plaque within this area. Pulpally and immediately below the necrotic zone, an area of demineralization was found which on the microradiographs appeared as a radiolucent zone. The zone showed a mineral gradient with an increasing mineral content towards the pulp. In the zone of demineralization a positive reaction occurred for sphingomyelin decreasing in a pulpal direction with increasing mineral content. A weakly positive reaction for cholesterol- and/or triglyceride-esters was also detected but only in the most pulpal part of the zone of demineralization; the intensity of the staining reaction was comparable to that found in normal dentin. In those areas which were represented by a sclerotized, radiopaque zone, only a very weak reaction for sphingomyelin, cholesterol-and/or triglyceride-esters could be observed of the same staining intensity as in normal dentin. The region between the lesion and the pulp showed the same staining intensity as normal dentin.

Cholesterol↗
PubMed1976

A quantitative microradiographic study of oral leukoplakias.

Biopsies from 13 oral leukoplakias and from normal tissue specimens in the contralateral region of each patient were examined histologically and microradiographically. Microradiographs of freeze-sectioned and freeze-dried sections were made and quantitative photometric analyses of the distribution of the dry mass concentration in different epithelial cell layers of both normal and pathologic specimens were performed. In each microradiograph, the thickness of the stratum corneum was determined. The results indicated that in oral leukoplakia two main changes occur in the epithelial surface layer, i.e. an increase of the thickness of the surface epithelial cell layer, and a formation of an epithelial surface zone of cell layers with different degrees of keratinization and varying dry mass concentrations.

Adult↗