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Biomedical subjects

F W Bora

Publications and source records attributed to F W Bora.

At least 37 records · Page 2Linked to original sources
PubMed1986

Electrical stimulation applied to bone and nerve injuries in the upper extremity.

In conclusion, electrical stimulation of bone has advanced from the laboratory to clinical reality. Despite the lack of good double-blind clinical studies, it is impossible to ignore the excellent results reported from numerous multicenter trials. Doubts and controversies will and should continue. Electrical stimulation has a definite place in the treatment of scaphoid nonunion as well as other failures of osteogenic biology in the upper extremity. The future may realize the enormous potential of electrical stimulation in areas of nerve repair, wound healings, or osteoporosis. The hand surgeon may soon be operating in the age of biophysics where he or she can charge by the kilowatt hour. Yet one should not become a mere technician, but understand the basic science of what one is doing and, above all, maintain a balanced and critical approach.

Arm Injuries↗
PubMed1985

Wrist arthroscope.

Explore the source record for details and available documents.

Arthroscopes↗
PubMed1984

Osteotomy of the distal radius with a biplanar iliac bone graft for malunion.

Active patients with malunions of the distal radius (more than one inch of shortening), with complaints of weak grip and limited forearm rotation and wrist motion, gained improved function as a result of a distal radial osteotomy with the insertion of a biplanar iliac bone graft. Those patients in the series with median nerve symptoms (about 50 percent) had their symptoms relieved with surgery. All patients felt that their forearm relationship was cosmetically improved.

Adolescent↗
PubMed1984

Free vascularized bone grafting for large-gap nonunion of long bones.

In conclusion, vascularized bone grafts provide a useful technique for difficult skeletal reconstructive problems. The advantages, indications, and method of this technique have been reviewed. The experience of the literature has been summarized, and our current experience with microvascular grafting was presented.

Adult↗
PubMed1984

Treatment of nonunion of the scaphoid by direct current.

Seventy-one per cent (12 of 17) of scaphoid nonunions previously treated by other methods united when the semi-invasive technique of electrical stimulation was used. Patient acceptance of this electrode technique is high, and morbidity is lower than in patients treated by iliac bone grafting. The treatment of nonunion of the scaphoid by the semi-invasive electrical stimulation technique is a reasonable alternative to bone grafting and provides a salvage procedure when bone grafting or other therapeutic modalities have failed.

Carpal Bones↗
PubMed1983

Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease.

Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palmitate and [14C]stearate in approximately equal yields as those obtained from "controls." No [14C]octanate was formed in any of the palmar-fat preparations. The lipids and fatty acid analysis revealed differences: (a) DDPF specimens were richer in free fatty acids, methyl esters of fatty acids and free-cholesterol than specimens of controls. (b) DDPF specimens contained less phospholipids. (c) DDPF specimens showed a significantly higher content of octanoate and other short-chain fatty acids than specimens of controls. The above findings are not incompatible with the results expected if some mild hypoxia occurred in DDPF; this has been suggested in the statistical correlations observed for this disease and alcoholism with liver involvement.

Adipose Tissue↗
PubMed1982

Compression neuropathy.

Some of the experimental, pathologic, and clinical features of extremity compression are reviewed with special reference to vulnerability of peripheral nerves to compressive forces at specific anatomic locations. Attention is directed toward syndromes resulting from mechanical factors, and it should be pointed out that a nerve can be compressed at more than one level. Localized peripheral nerve compression is common in clinical medicine; carpal tunnel syndrome is the most common example. Physicians who maintain a high index of suspicion to the signs and symptoms of peripheral nerve compression will diagnose and treat these conditions earlier and thereby reduce the number of patients who develop permanent functional disabilities.

Axilla↗
PubMed1981

Radial club-hand deformity. Long-term follow-up.

In 1970, the results of the treatment of fourteen patients with radial club hand were reported. Ten years later, we re-examined ten of these patients. There was little change in the measurements of ulnar bowing or ulnar length over the intervening decade, and the treated patients retained the cosmetic and functional improvement previously described. They also adapted satisfactorily to performing activities of daily living.

Adolescent↗
PubMed1980

The biomechanical responses to tension in a peripheral nerve.

The biomechanical adjustments rat sciatic nerves make to tension were studied 7 weeks after experimental nerve repair. Nerve tissue adjusts to tension by increasing its compliance if stretched within its physiological limits. Anatomical changes observed in the nerve tissue 7 weeks after stretching apparently accounts for the nerves extensibility, a biomechanical adjustment that helps preserve nerve continuity during the joint extension phase of extremity rehabilitation.

Adaptation, Physiological↗
PubMed1978

Osteoid osteoma of the carpal bones.

Three cases of osteoid osteoma of the carpal bones are described, with a review of the literature. The scaphoid is the carpal bone involved most frequently. Typically the lesions are painful and respond to aspirin. Roentgenologic finding of the central area of lucency surrounded by sclerotic bone often is diagnostic. Block excision with bone grafting is an acceptable method of treatment.

Adult↗
PubMed1978

A comparison of epineurial, perineurial and epiperineurial methods of nerve suture.

An experimental study was designed to compare the effectiveness of epineurial, perineurial, and combined epineurial and perineurial suture after laceration of the sciatic nerve in rabbits by measuring biochemical determinations in the distal stump of the nerve after both immediate and delayed repairs. Relatively more myelin was found in the immediate epineurial group, which suggests that nerve regeneration was most rapid in this group. Additional experiments are needed to evaluate end-organ reinnervation which is another criterion for evaluating the best method of nerve suture in clinical situations.

Animals↗
PubMed1978

Neuroma scar formation in rats following peripheral nerve transection.

Utilizing a sciatic nerve-transection model in rats, we studied the collagen content of normal control nerves, the long-term collagen accummulation in the distal stump of the transected nerve, the content of collagen of the posterior tibial nerve distal to the transection, and the myofibrosis of the gastrocnemius muscle. The distal stump of the sciatic nerve accumulated significant amounts of collagen with time but the posterior tibial nerve at a distance from the site of transection showed no progressive collagen accumulation. The histologically evident myofibrosis of the denervated gastrocnemius muscle was shown to be the result of a selective loss of muscle elements and not of an accumulation of collagen. cis-Hydroxyproline, a proline analogue, limited neuroma formation following neurorrhaphy. The findings suggest that the results of delayed repair of nerves should not be impaired by intraneural scarring if enough of the transected nerve beyond the point of intraneural scar formation is resected.

Animals↗
PubMed1976

A study of nerve regeneration and neuroma formation after nerve suture by various techniques.

The effectiveness of epineurial, perineurial, and a combined epiperineurial methods of nerve suture in the severed sciatic nerve of rabbits was studied by biochemical assay of the collagen just distal to the neuroma and the collagen and myelin of the posterior tibial nerve. Repairs were done both immediately after severance and in a separate group 3 weeks later. More collagen was found near the neuroma in the immediate epineurial group, but 60 per cent of the normal myelin was found in the posterior tibial nerve after the immediate epineural suture compared to 28.3 per cent in the immediate perineurial group.

Animals↗
PubMed1976

Gliding function following flexor-tendon injury. A biomechanical study of rat tendon function.

Gliding function of flexor tendons one hour to eight weeks after a standard injury was studied in rat digits by determining terminal force of flexion, tendon excursion, and work of flexion using a tensile testing machine. A rapid decrease in gliding occurred within hours of injury, indicating that the postoperative hematoma and edema restrict gliding long before collagenous adhesions are synthesized. The improvement in gliding function with time implies that fibrous adhesions can be remodeled. Surgical methods and therapeutic agents, therefore, should be directed toward limiting early tissue injury and seeking ways to enhance the late remodeling of fibrous peritendinous adhesions along functional lines.

Animals↗
PubMed1975

cis-hydroxyproline limits work necessary to flex a digit after tendon injury.

Present surgical procedures for the repair of tendon injury are complicated by formation of peritendinous collagenous adhesions which restrict tendon gliding. Several sensitive biomechanical tests have been developed to quantitate peritendinous restriction of gliding. Using these tests it was found that cis-hydroxyproline significantly limits net collagen accumulation following tendon injury in a rat model and decreases the adhesive restraints to tendon gliding. cis-Hydroxyproline and other proline analoques offer a method for specifically preventing excessive collagen formation.

Animals↗