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Biomedical subjects

F Romero

Publications and source records attributed to F Romero.

At least 91 records · Page 5Linked to original sources
PubMed1982

G-6-PD Guadalajara. A new mutant associated with chronic nonspherocytic hemolytic anemia.

This paper describes a new G-6-PD variant designated Guadalajara, which was found in a Mexican boy suffering from chronic hemolytic anemia. The red cell enzyme activity of the subject is about 14%. The mutant enzyme showed rapid electrophoretic mobility, slightly increased affinity for glucose-6-phosphate, slightly decreased affinity for NADP+, moderately elevated utilization of substrate analogues, and normal heat stability, pH curve, and inhibition by NADPH. G-6-PD Guadalajara differs from all previously reported variants and is the first variant associated with chronic hemolysis found in Mexico.

Anemia, Hemolytic, Congenital↗
PubMed1982

Screening for inborn errors of the erythrocyte metabolism in Northwestern Mexico.

Data from a program aiming to the detection of inborn errors of the erythrocyte metabolism (IEEM) in Northwestern Mexican populations are presented. 5,998 individuals were studied and divided in 5 groups: a) 1,022 full-term newborns without jaundice; b) 872 randomly selected full-term newborns; c) 3,243 full-term newborns with jaundice; d) 54 patients with hemolytic anemia, and e) 807 professional blood donors. In groups b, c and d screening for 9 out of 14 IEEM clearly associated with hemolysis was carried out by means of enzymatic fluorescent procedures. In groups a and e only G-6-PD deficiency was investigated. The results suggest that 0.34%, 0.77%, 24% and 0.37% of the individuals from groups b, c, d and e, respectively, have an IEEM. The frequency of G-6-PD deficiency was 0, 0.43%, 1.1%, 30.3% and 0.37% in the males from groups a, b, c, d and e, respectively. The IEEM as a cause of neonatal jaundice seem not to be a public health problem in the studied populations. Systematic screening for: 1) G-6-PD deficiency in newborns with jaundice and 2) IEEM in patients with hemolysis, is recommended.

Anemia, Hemolytic↗
PubMed1980

Study of tuberculous meningitis by CT.

Computed tomography is a very valuable method by which the pathogenic evolution of tuberculous meningitis may be followed, thereby facilitating its differential diagnosis and controlling the efficiency of therapy. The initial miliary tuberculosis in the brain, very often unaccompanied by neurological symptoms, may offer very evident CT images. CT may also demonstrate the fibrogelatinous exudate which fills the basal cisterns and surrounds the arterial vessels which cross this region. Because of this, secondary arteritis is frequent and may be indirectly detected by CT in the form of foci of ischemic infarcts. Tuberculomas may be multiple, and are found equally in the cerebral and the cerebellar parenchyma. These tuberculomas present different images on CT, depending on the evolution of the disease at that moment. Hydrocephalus is a common complication of TM and is caused by a lack of reabsorption of the cerebrospinal fluid, or by an obstructive lesion in the ventricular drainage pathways due to a tuberculoma. This complication is usually easily identified by CT, which, moreover, permits the control of its evolution.

Adult↗
PubMed1980

[Porphyrin excretion in normal (author's transl)].

Porphyrin excretion in normal subjects was studied by solvent extraction procedures and by thin-layer chromatography of their methyl-esters. The mean value of the urinary coproporphyrin fraction was significantly higher in males than in females. Taking age also into account this difference was not significant in subjects under 20 years of age. Within the same sex, age did not have any influence on this coproporphyrin fraction. Neither of these two factors, i.e. sex and age modified the mean values of uroporphyrin fraction. Males and females showed similar amounts of fecal copro and protoporphyrin fractions. The thin-layer chromatographic urinary pattern revealed a minor porcentual value of octo-carboxylic-porphyrin in males, due mainly to a lower amount of porphyrin in the 20-40 year, period, when males also showed a decreased value of heptacarboxylic-porphyrin. Neither sex nor age modified the fecal chromatographic porphyrin pattern. Di-carboxylic porphyrins were always predominant, but theri appraisal was very frequently interfered by the presence in feces of fluorescent substances with a Rf similar to tri-carboxylic-porphyrin but with a pheophytinlike spectra.

Adolescent↗
PubMed1978

Contribution to the study of the arterial nutrition of the cervical spinal cord.

The feeding of the anterior spinal artery of the cervical cord is very poor. Angiographic studies have shown that only two to three radiculomedullar arteries assure the feeding of this arterial axis. Since it is possible that smaller feeding arteries exist, which are not visible on a conventional X-ray study, we have reviewed cases with arteriovenous aneurysms or vascularized tumors in the cervical region, and obstructions of the vertebral arteries. In these cases, the feeding arteries may be hypertrophic. In spite of being hypertrophic, their number is not increased, and the statistical proportion is the same as in the studies carried out in normal cases.

Adult↗
PubMedDate not supplied

[Giant fecal impaction as a cause of female incontinence (Fecaloma) and bladder instability. Contribution with one case].

We present a case of a 60 years old female patient, with previous depressive disorders, an attempted suicide with pelvic injuries, who comes showing two years evolution of emergence incontinence. The was diagnosed with a giant fecal impaction occuping almost all the pelvic zone and leading to a bladder displacement and right ureteral ectasis.

Constipation↗