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Biomedical subjects

F Pardo

Publications and source records attributed to F Pardo.

At least 109 records · Page 6Linked to original sources
PubMed1992

[Cancer of the esophagus (I): its epidemiological, clinical and diagnostic assessment according to histological type].

From 1975 to 1991, sixty-eight patients were treated with surgery for esophageal cancer at the Clínica Universitaria de Navarra. This study involves an analysis of epidemiologic and predisposing risk factors in relation with the histologic type of tumor: epidermoid carcinoma vs. adenocarcinoma. The difference in mean age of males (60.5 yrs.) as compared with that of females (48.7 yrs.) was statistically significant (p < 0.05). Likewise, the mean age of patients with epidermoid carcinoma (57.8 yrs.) was significant lower (p < 0.01) as compared with that of those with adenocarcinoma (66.3 yrs.). Smoking and alcoholism were common in the group of patients with epidermoid carcinoma, while Barrett's esophagus and hiatal hernia were frequently seen in patients with adenocarcinoma. Dysphagia was the most frequent symptom both at the start of disease (75%) and with the diagnosis established (96.7%). There was no significant difference in the symptomatology of patients with one type of tumor or the other. The efficacy of ancillary diagnostic procedures such as barium swallow, esophagoscopy, computerized tomography and biopsy were likewise assessed. The most frequent site of tumor was at the middle third, with majority of patients being at clinical stage 1-2 of disease at the time of diagnosis.

Adenocarcinoma↗
PubMed1992

[Cancer of the esophagus (II): the results of surgery, anatomicopathological study and patient survival].

We present a retrospective study of 68 esophageal cancer patients treated with surgery between 1975 and 1991. Results showed a resectability of 73.5% with the most frequent surgical approach being a Lewis esophagectomy. The mean hospitalization time was 24.7 days with a postoperative mortality of 7.3%. Other complications included anastomotic leakage, wound infection, sepsis and pulmonary disorders. Over-all survival at 3 years was 17.3%, reaching 24% in resected patients. Survival according to lymph node involvement was 13.4% for lymph node positive patients and 34.5% for node negative patients. According to histopathologic stage, survival rates were 34.6% and 8.59% for early and advanced tumor respectively, the difference being statistically significant using the Mantel-Haenszel test.

Actuarial Analysis↗
PubMed1991

Fetal outcome among pregnancies in natural family planning acceptors: an international cohort study.

This international, multicenter, prospective cohort study examines the outcome of pregnancies associated with aging gametes. Comparing pregnancies conceived at or near the peak mucus phase with those occurring before or after the peak provides a means of evaluating the effect of aging gametes. The outcome criteria are (1) rates of spontaneous abortion, (2) low birth weight, and (3) congenital malformations. Preliminary analysis shows a trend toward increased spontaneous abortion with aging gametes in certain subsets (women with prior pregnancy losses) but no effect on birth weight. Too few method failures have yet been studied to make a definitive statement on congenital malformations.

Family Planning Services↗
PubMed1991

Müllerian defects in women with normal reproductive outcome.

The incidence of uterine congenital anomalies because of müllerian defects in the normal fertile population is 3.2% (22/679). Twenty (90%) of them are septate uteri, whereas a bicornuate (5%) and a didelphys uterus (5%) have been also found in this population. Based on these findings, we question the usefulness of the septum resection in patients with septate uterus and no previous reproductive failure.

Adult↗
PubMed1991

[Spontaneous rupture of a hepatic adenoma associated with hepatic peliosis].

Benign hepatic tumors, although rare, are each time encountered more frequently, occasionally posing diagnostic and therapeutic problems. Within this group of tumors, hepatic adenomas are the least common, although its increasing incidence could be attributed to the use of contraceptives or to the availability of newer diagnostic methods. A hepatic adenoma presenting with spontaneous rupture at diagnosis is associated with a mortality of 20%, for which emergency hepatectomy is indicated and usually carried out under unstable hemodynamic conditions. In this report, we present the case of a 30 year old female with three previous pregnancies carried to term, without any history of intake of contraceptive or hepatotoxic drugs, who presented with spontaneous rupture of a large hepatic adenoma associated with hepatic peliosis.

Abdomen, Acute↗
PubMed1991

[Incidence and clinical manifestations of arterial complications of liver transplantation. Personal experience with 57 transplants].

The vascular complication remains one of the main cause of graft failure after orthotopic liver transplantation (OLT). Its incidence has been documented between 5-18%. Due to its lethal evolution, the early diagnosis and emergency treatment are crucial: early retransplantation, arterial reconstruction. Seven out of 57 OLT (12.2%) performed in 53 patients developed arterial complications: 4 arterial thrombosis (7.0%),--3 were retransplanted--; 3 ruptured arterial aneurysms and 1 child who developed hemobilia secondary to an arterio-biliary fistula. The clinical presentation of hepatic artery thrombosis was related with the post-transplant time. Due to the variability in the clinical presentation of this complication, angiographic study should be performed in any episode of unexplained graft dysfunction.

Adolescent↗
PubMed1991

[Resistance of Streptococcus pneumoniae in Galicia].

We studied the antibiotic sensitivity of 130 Streptococcus pneumonia strains isolated from respiratory samples (96 cases), blood (13 cases), CSF (6 cases), ocular secretions (5 cases) and other origins (10 cases). High-level penicillin-resistance was found in 13.08% of strains, and intermediate-level penicillin resistance was also found in 22.3% of strains. A multiple-antibiotic resistance pattern was shown by 80.44% of all penicillin-resistant strains. Resistance rates found against antibiotics were as follows: tetracycline, 41.53%; chloramphenicol 17.69%; cotrimoxazole, 16.92% and erythromycin 6.92%. All isolated strains were sensitive to rifampin and vancomycin.

Drug Resistance, Microbial↗