Search PubMed⌕ Search

Biomedical subjects

F Matsubara

Publications and source records attributed to F Matsubara.

At least 199 records · Page 11Linked to original sources
PubMed1981

Correlation between thyroid peroxidase activity and histopathological and ultrastructural changes in various thyroid diseases.

A morphological and biochemical study was performed on thyroid tissue with various thyroid diseases. The thyroid peroxidase (TPO) activity of normal thyroid tissues ranged from 2.6 to 7.0 mGU/mg DNA. The activity was low in adenomas and extremely low in carcinomas, and there was no significant relationship between the histological subclassification of follicular adenomas (simple, colloid, oxyphil) and TPO activity. The activity was various in the cases of chronic thyroiditis, ranging from non-detectable to 9.8 mGU/mg DNA, and the TPO activity showed a close correlation with the degree of lymphoid cell infiltration of the diseases. In the seven cases of Graves' disease, the values were high, though the elevation was not so remarkable in three cases which had already been euthyroid or slightly hypothyroid after long-term treatment. By means of subcellular fractionation, more than 50% of peroxidase activity was shown to be localized in the microsomal pellets, and this result well coincided with the electron microscopic findings of prominent development of rER.

Adenoma↗
PubMed1980

Primary localized amyloidosis of bladder.

A case of primary localized amyloid tumor of the bladder is described, which was confused with neoplasm by cystoscopic, urographic, and other studies. Surgical specimens obtained by transurethral resection were diagnostic.

Aged↗