Search PubMed⌕ Search

Biomedical subjects

F Gyntelberg

Publications and source records attributed to F Gyntelberg.

At least 127 records · Page 7Linked to original sources
PubMed1985

Blood pressure and other cardiovascular risk factors of long-term exposure to lead.

The coronary risk profile was studied for 96 heavily exposed lead smelter workers employed between 9 and 45 years and for a reference group not exposed to lead but comparable with respect to age, sex, height, weight, social grouping, occupational status, and alcohol and tobacco consumption. The lead smelter workers had a little higher diastolic blood pressure and significantly more ischemic electrocardiographic changes, and their high-density lipoprotein levels were lower than the corresponding values of the reference group. The lead workers with electrocardiographic changes had higher blood pressures than the referents with corresponding changes. These findings indicate a higher coronary risk profile for the examined lead smelter workers. The study supports the hypothesis of a positive association between lead exposure and arteriosclerosis and high blood pressure.

Adult↗
PubMed1983

Subjective symptoms after long term lead exposure in secondary lead smelting workers.

The prevalence of lead induced subjective symptoms was evaluated by a standardised questionnaire in a group of 96 workers employed between nine and 45 years in a secondary lead smelting works. A control group of 96 non-lead exposed subjects, matched for age and sex, were chosen from the Glostrup population study. Blood lead concentrations were in excess of 60 micrograms/100 ml in about 30% of the lead workers. Zinc protoporphyrin levels were found to be higher than 500 mumol/Hb in nearly 18% of the lead workers. The prevalence of fatigue, headache, sleep disturbance, and digestive symptoms (constipation and colic) were not higher in the lead exposed group. The body weight showed no significant difference in the two groups. Nervousness was four times more frequent in the control group. The results indicate that subjective symptoms are useless as indicators of incipient lead poisoning.

Adult↗
PubMed1983

Epidemiology of hearing impairment in male adult subjects at 49-69 years of age.

As part of a cross-sectional prevalence study aimed towards elucidation of the relationship between physical fitness and coronary heart disease, information concerning the hearing ability and hearing disorders was included into postal questionnaires. These were distributed to 5 050 male subjects at a median age of 53 years, range 45-65 years, and employed in public and private Copenhagen companies. A random sample of subjects was drawn from the respondents and subjected to audiological examination (N = 206). The prevalence of hearing impairment, based on the criterion of an audiometric pure-tone threshold averaged over 500, 1 000, 2 000 and 4 000 Hz greater than or equal to 25 dB HL, is 35 +/- 5%, which compares fairly well with the number of 44 +/- 7% complaining of subjective hearing impairment. Only 16 +/- 5% had normal hearing sensitivity, and 38 +/- 7% had permanent, noise-induced hearing impairment. The prevalence and characteristics of hearing impairment are compared with a recent English epidemiological investigation using an identical average of pure-tone thresholds as criterion for hearing impairment. Furthermore, the present results are considered in view of different criteria for hearing impairment and their relation to subjective complaints of reduced hearing ability. Based on the anamnesis, the pure-tone audiometric data and additional tests used for topical diagnostic purposes, the prevalence of various aetiologies of hearing impairment is indicated for the male age group in question.

Aged↗
PubMed1982

Coronary risk factors and plasma sex hormones.

Recent studies have reported higher plasma estradiol levels in male survivors of acute myocardial infarction. This finding has raised the possibility that hyperestrogenemia may consitiute a separate coronary risk factor. In 443 men, aged 30, 40, 50, and 60, we assessed the relationship between plasma levels of estradiol, testosterone, and testosterone-binding globulin and coronary risk factors: fasting plasma concentrations of triglyceride, cholesterol, and high-density lipoprotein, blood pressure, and smoking and leisure-time physical activity patterns. Plasma estradiol concentrations were found to correlate significantly with body weight. After adjustment for this association, we found that the mean plasma estradiol concentration still was significantly higher in smokers than in nonsmokers. No other correlation could be estabilished between plasma hormone levels and coronary risk factors. The relative hyperestrogenemia reported in men with previous myocardial infarction may be due to an effect of smoking but may also reflect the relationship between body weight and plasma estradiol levels. Future studies should consider the demonstrated association between plasma estrogen levels and smoking.

Adult↗
PubMed1982

Absence of peripheral neuropathy in long-term lead-exposed subjects.

The safety of a blood lead concentration of 70 microgram/100 ml as a hygienic border value with regard to development of lead neuropathy was tested in 95 employees, who had been exposed occupationally to lead for more than 9 years. The blood lead concentration was slightly above the border value in nine subjects, while the erythrocyte-Zn-protoporphyrin concentration was significantly elevated in 81 subjects, indicating an abnormal accumulation of metabolically active lead. None of the group showed clinical evidence of peripheral neuropathy, and the vibratory perception thresholds as well as motor conduction data from the median, radial, and common peroneal nerves were normal, as compared with an age-matched control group of 21 non-exposed normal subjects. The amplitude ratio between proximally and distally evoked muscle action potentials was normal in all lead-exposed subjects. These findings suggest that lead-exposed subjects are well protected against peripheral lead neuropathy, when blood lead levels are kept below the hygienic border value.

Adult↗
PubMed1981

Smoking and risk of myocardial infarction in Copenhagen men aged 40-59 with special reference to cheroot smoking.

A 5-year and 7-year follow-up study on 5249 Copenhagen men showed a relationship between smoking habits at the time of entry into the study and incidence of lethal and non-lethal myocardial infarction. With a relative risk of 4.2, heavy cheroot smokers had a higher risk of myocardial infarction than cigarette smokers (relative risk 2.1) and never-smokers. A multiple regression analysis indicates that cheroot smoking is an independent coronary risk factor.

Adult↗
PubMed1981

Blood pressure reduction by change in life style. The CVD intervention study in Glostrup.

In a controlled, primary intervention, cardiovascular survey on 928 men and women aged exactly 30, 40, 50 & 60 years, a significant reduction (about 5 mmHg) was found in systolic blood pressure mean difference before and after intervention between the intervention- and control group. The observation time was 7 months. Most of the twentynine drop outs were excluded for personal reasons or because of antihypertensive treatment. A reasonable explanation for the blood pressure reduction is a change in life style, in the intervention group. The subjects in the intervention group increased physical activity and decreased fat and salt intake in contrast to the control group (p less than 0.001, 0.005).

Adult↗
PubMed1981

Cholesterol, high density lipoprotein-cholesterol (HDL) and cholesterol/HDL-ratio versus arterial blood pressure.

In a cardiovascular survey of 928 men and women aged exactly 30, 40, 50 & 60 years, a correlation between serum cholesterol, cholesterol/HDL-ratio and arterial blood pressure was found. This correlation was indirectly caused by mutual correlations to relative weight and age as a final result found after multiple rank correlation analysis in each sex. HDL was not correlated to arterial blood pressure at all.

Adult↗