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Biomedical subjects

F Gyntelberg

Publications and source records attributed to F Gyntelberg.

At least 145 records · Page 8Linked to original sources
PubMed1980

Skin perfusion pressure on the legs measured as the external pressure required for skin reddening after blanching: a photo-electric technique compared to isotope washout.

The skin perfusion on the calf was measured photo-electrically and by isotope washout technique using external counter pressure by a blood pressure cuff. By the photocell the skin blanching threshold external pressure (BTEP) was recorded on histamine flared red skin. By isotope washout technique the skin blood flow cessation external pressure (FCEP) was recorded using intra-dermal [131I-]-antipyrine mixed with histamine in estimating the skin blood flow. The external pressure was measured with an airfilled plastic cushion connected to a mercury manometer. Over a wide range of pressures as obtained from twenty patients with occlusive arterial disease of the legs, five normal subjects and eleven patients treated for arterial hypertension the values of the two different methods were highly significantly correlated (r = 0.97, P < 0.001). On average the BTEP was equal to the FCEP: 83.9 mmHg (range 18-187) compared to 80.8 mmHg (range 18-158) (P > 0.1). A normal material was obtained from twenty-four subjects measured on the thigh, calf and ankle; the average gradients between the auscultatory brachial mean blood pressure and the BTEP were: thigh 10.7 mmHg (SD 12.7); calf 4.0 mmHg (SD 12.1); ankle 5.1 mmHg (SD 8.7). As compared to the intra-arterial blood pressure the BTEP was found to lie close to the mean blood pressure in normal subjects as well as in hypertensive subjects. The present data indicate that the skin perfusion pressure on the legs can be measured by the rapid photo-electric technique. The clinical application and sources of error are discussed.

Adult↗
PubMed1980

Physical fitness and risk of myocardial infarction in Copenhagen males aged 40-59: a five- and seven-year follow-up study.

Physical fitness and risk of myocardial infarction in Copenhagen males aged 40--59: a five- and seven-year follow-up study. Scand j work environ health 6 (1980) 170--178. A 5-a follow-up study on 5,249 Copenhagen males showed that the incidence of myocardial infarction was related to the level of physical fitness at the time of entry into the study, as determined by the indirect measurement of maximal oxygen uptake. Men having a physical fitness level within the lowest fifth of the total sample has a three times higher incidence of myocardial infarction than men in the upper two-fifths. This increased risk was independent of smoking habits and serum cholesterol level but may be partly or entirely dependent on blood pressure levels, as shown by use of a multiple logistic regression analysis. The men with the heaviest occupational physical activity had a somewhat higher risk of myocardial infarction than men with sedentary jobs. The data on leisure-time physical activity and risk of coronary heart disease indicated that only physical activity inducing a physical training effect is related to decreased risk.

Adult↗
PubMed1978

Antihypertensive treatment with pindolol in one or two doses. A comparative trial.

A comparative trial was carried out in 21 patients on the antihypertensive effect of pindolol given once or twice a day. A change-over design was employed, with two treatment schedules and four treamtnet periods of six weeks each. No statistically significant difference was found in BP lowering effect between one and two daily doses. It is unlikely that a switch from pindolol twice daily to the same amount once daily will crease the BP by more than at most 1.0 mmHg systolic and 2.2 mmHg diastolic, or decrease it by more than 2.7 and 1.0 mmHg, respectively. It is concluded that pindolol given once daily can be recommended.

Adult↗
PubMed1977

Plasma triglyceride lowering by exercise despite increased food intake in patients with type IV hyperlipoproteinemia.

Exercise can lower fasting triglyceride levels (TG). This study was undertaken to determine whether the exercise-induced decrease in TG is the result of a negative caloric balance. Five subjects with primary type IV hyperlipoproteinemia were given diets comparable in composition to their usual diets. During one experimental period the subjects exercised while maintaining their usual caloric intakes. During another experimental period their caloric intake was increased to compensate for the exercise-induced increase in energy expenditure. The exercise, which consisted of 30 min of treadmill walking per day for 4 days, resulted in a progressive decrease in TG. The reduction in TG, which averaged 120 mg/100 ml, occurred regardless of whether or not the increase in caloric expenditure was compensated for by an increase in food intake. The decrease in TG was limited to the very low density lipoprotein fraction. No significant changes occurred in total plasma cholesterol concentration or in the distribution of cholesterol between the lipoprotein fractions. Fasting plasma glucagon concentration was constant for each individual and was unaffected by the exercise. The finding that exercise induces a decrease in TG despite increased food intake indicates that the TG lowering effect of exercise is not mediated by a negative caloric balance.

Adult↗