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Biomedical subjects

F Gaillard

Publications and source records attributed to F Gaillard.

At least 73 records · Page 4Linked to original sources
PubMed1987

[Immunohistochemical study of 4 cases of mucoid and argyrophilic carcinoma of the breast].

Three to 5% of breast carcinomas are argyrophilic, including some which are mucinous and thus "composite", whereas there are no argyrophilic cells in normal breast nor in benign breast pathology. This raises the problem of the origin and type of these argyrophilic cells. We carried out a histologic and immunohistochemical study in 4 such cases of mucoid tumors containing at least 50% argyrophilic cells. Two of these tumors presenting node involvement were also studied immunohistochemically. The histologic study showed colloid and intragalactophoric proliferation areas in cell cases and some endocrine areas in 2 out of 4 cases. Argyrophilic cells were present in all of these areas. True mucoargyrophilic amphicrine cells were found primarily in colloid areas. None of these tumors were argentaffin. Immunohistochemical study was performed by the PAP method using antibody directed against VIP, ACTH, PP, somatostatin, bombesin, calcitonin, gastrin, prolactin and GH. Three out of four tumors were positive with VIP. Moreover one of them contained ACTH cells and a metastasis of this tumor contained bombesin cells. No tumor was positive with the other anti-sera tested. This study is related to the rare series in the literature which report secretion of ACTH, catecholamins, bombesin, gastrin, VIP, PP, somatostatin, prolactin, etc. The number of cases reported to date remains too low to show a significant prognostic difference between amphicrine tumors and other mammary carcinomas.

Adenocarcinoma, Mucinous↗
PubMed1986

The velocity function of ipsilateral visual units in the frog optic tectum: comparison with retinal ganglion cells.

Ipsilateral retino-tecto-isthmo-tectal units in frogs were commonly classified in two groups (I1 and I2) according to their functional properties. Quantitative measurements of their discharge in response to automatically moved targets are described below for the first time. Results show that the velocity function of these units can be expressed by a power function respectively similar to that described earlier (see ref. 6) for R2 and R3 retinal ganglion cells. The existence of mixed 'sustained' units is also discussed.

Animals↗
PubMed1986

[Algodystrophy in children and young adults with low isotope retention in the bones. Apropos of 5 cases].

The authors report 5 observations of young adults, 3 teen-agers and 2 children suffering from algodystrophy, and in whom isotopic exploration of the skeleton disclosed a clear bony hypofixation during the entire evolution. These observations confirm their 1981 work concerning a young adult suffering from algodystrophy with isotopic bony hypofixation. Recent Canadian and American studies emphasize also the frequency of isotopic hypofixation in children algodystrophy. It seems, therefore, that isotopic bony hypofixation (linked perhaps to a decreased blood flow), is rather specific of algodystrophy in young subjects.

Adolescent↗
PubMed1986

[Value of absorbable stapling in digestive surgery? Experimental study comparing TA metallic stapling, TA absorbable stapling and manual sutures].

Absorbable staples, recently available for TA 55 instrument, has not been yet evaluated in gastro-intestinal surgery. This experimental work was designed to determine the feasibility and the reality of the advantages of the new material: the wound healing process of 3 techniques of intestinal closure (metal staples, Lactomer absorbable staples and polyglactin sutures) were compared. A double Roux en Y loop was performed on 9 dogs: each end was closed by one of these techniques, and recuperated at regular intervals (3 samples by dog). Twelve sutures were examined at 10 post-operative days, 14 at 25 days, and 10 at 130 days. Macroscopic examination showed major inflammatory adhesions around absorbable staples. Two fistulae have complicated absorbable stapling versus 0 with the 2 others techniques. Histologic review showed greater tissue trauma with Lactomer staples than metal staples; intense and prolonged inflammatory reaction was seen around absorbable staples, while metal staples were well tolerated. The difference in design of the 2 staples can explain the differences in the healing process. In spite of the interest for absorbable material, our experimental study shows the present superiority of the metal stapling and prompts improvements of absorbable staples for reliable use in gastro-intestinal surgery.

Animals↗
PubMed1985

Binocularly driven neurons in the rostral part of the frog optic tectum.

Receptive field (RF) properties of binocular neurons lying in the rostral part of the optic tectum of the frog (Rana esculenta) were studied electrophysiologically using conventional visual stimuli. They were classified into five groups: group 1 neurons have indefinite RF; group 2 neurons are total-field (T6) neurons; group 3 neurons have RFs covering a quadrant of the frontal visual field; group 4 neurons resemble T1(1) and T1(3) subclasses described earlier; and finally group 5 neurons look like small-field binocular neurons and are called T7(B). Moreover, RF disparity measurements conducted in all groups suggest that group 4 neurons support the estimation of binocular distance. This problem is discussed.

Action Potentials↗
PubMed1984

[Small-field receptor monocular neurons in the optic tectum of frogs: analytical properties and problems of classification].

Small field (less than 10 degrees) monocular neurons were electrophysiologically recorded from the rostral part of the frog's optic tectum. When tested with conventional stimuli, these neurons displayed rather common properties. Two main groups could nevertheless be defined. In group I neurons (30%), habituation to repetitive stimulations was present but the responses never disappeared completely. These neurons also showed brief OFF-ON responses to light spot stimulations. Group II neurons (70%) only responded to the first presentations of moving targets. Responses to light spot stimulation were different: 25% of them (group IIa) showed OFF-ON responses, 19% (group IIb) presented only OFF responses and 26% (group IIc) gave no response. The receptive fields had no null region and extended about equally in all directions. There was no correlation between RF diameters and response types. Small field visual neurons represented approximately 37.7% of the whole neuronal population. The problem of their place in the usually used classification is discussed.

Animals↗
PubMed1983

Recovery as a mind-brain paradigm.

Struck by the sometimes contradictory representations of recovery that rehabilitation specialists resort to in their professional activity, we examine five models covering the whole range: neuronal regeneration, neuro-psychological plasticity, intersensory compensation, behavioural relearning, and finally the cognitive and affective concern for a new life. This exercise and a review of the literature lead us to consider a two-way relationship between psychological adaptation and nervous restoration. We think that reference to a integral model of recovery is essential for an inter-disciplinary team to find all the means for helping each individual case. The implications appear to be valid not only for rehabilitation, but also for the daily care of the chronically handicapped: it is suggested that they should benefit from a comparative study in which they experience the different modes of action. In special education also, mentally handicapped children should be trained by different methods tested with each child; a sequential programme of alternating periods of verbal, visual, and bodily training is proposed.

Adaptation, Psychological↗
PubMed1983

[Comments on the topography of the crossed isthmo-tectal projection in the frog].

In this work, we show that cortical cells of the contralateral nucleus isthmi remain unlabelled when HRP deposits are made in the monocular zone of the optic tectum. On the other hand, labelling is present with deposits made in the binocular tectal region. This result would confirm that in frogs the crossed isthmo-tectal pathway is only concerned with ipsilateral retinotectal messages.

Animals↗
PubMed1983

[Treatment of florid oral papillomatosis. Apropos of 10 cases].

Florid oral papillomatosis is a well defined, not exceptionally observed clinical entity of unknown pathogenesis. The exuberant lesions are characterized by their benign appearance on histology, but this is usually associated with a marked capacity for progression and recurrence and a tendency for epitheliomatous degeneration. Based on a review of cases in the published literature and a series of ten patients treated personally, it would appear that radiation therapy should be formally excluded, and that the treatment of choice is by wide excision associated, whenever possible, with reconstructive surgery.

Aged↗
PubMed1983

[Inflammatory pseudotumor of the liver. Unusual course of an unrecognized abscess? Apropos of a case].

The authors report the case of an hepatic tumor occurring in a 46 years old man admitted for a long-way fever. After hepatectomy, the microscopic examination showed fibro-xantho-granulomatous aspects with micro-abscess, tuberculoid nodules and a portal phlebitis. These lesions have been interpreted as an "inflammatory pseudotumor". The tumor had microscopic likenesses with inflammatory pseudotumors of the lung of which an infectious origin is only suggested. In the literature, the authors found only two cases of inflammatory pseudo-tumor of the liver, in which micro-abscess are not mentioned. The feature helps the authors to find some similarities between their tumor and a particular type of granulomatous abscess of the liver.

Diagnosis, Differential↗