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Biomedical subjects

F Gaillard

Publications and source records attributed to F Gaillard.

At least 91 records · Page 5Linked to original sources

[Anatamo-pathologic aspects of gold-salt induced cholestasis. Report of two cases with ultrastructural study (author's transl)].

The authors report two cases of gold-salt-induced cholestasis. They make a review of the thirteen cases previously related in the literature ; the cholestasis was constant, the hepatocytic necrosis was unusual and the gold-salts were difficult to visualize in the liver biopsy and more especially at the ultrastructural level. The immunological mechanism of hypersensibility is well established ; the possibility of an associated hepatotoxicity is debated.

Aged↗

Tectal processing of visual signals from the caudalmost part of the frog visual field.

Electrophysiological investigations restricted to the caudomedial part of the optic tectum show that the caudalmost part of the frog's visual field appears preferentially analyzed by class-2 and class-3 retinal ganglion cells and integrated by monocular T5 neurons even though this spatial region is seen by the two eyes and doubly represented on each tectum. This apparent preponderance for three types of contralateral visual units is discussed on the basis of the animal's behaviour.

Animals↗

[Diffuse pulmonary amylosis. Apropos of 2 cases associated with Waldenstrom's disease].

Diffuse pulmonary amyloidosis is rarely reported in systemic amyloidosis. We report two patients with Waldenström's macroglobulinemia in whom pulmonary amyloidosis was revealed by a diffuse interstitial syndrome without severe functional impairment. Amyloid pulmonary deposits are anatomically frequent and are often associated with cardiac amyloidosis. They must be evoked more frequently in the diagnosis of diffuse interstitial patterns, particularly in patients with primary amyloidosis or dysglobulinemia.

Aged↗

Residual tectal projection from the contralateral central retina of the frog after homolateral optic nerve and main optic tract section. A possible input from the axial optic tract.

After homolateral (right) optic nerve and main optic tract section a residual visual activity originating from the contralateral (left) central retina was recorded in the right optic tectum. Units were classified in three groups according to their receptive field properties: (1) slow-adapting units analogous to class 3 retinal ganglion cells; (2) fast-adapting postsynaptic units; (3) visual neurons. All of these units have in common a receptive field located near the projection of the left eye optic axis. Evidence that these units belong to the same visual pathway (i.e., the axial optic tract) is discussed.

Action Potentials↗

Mapping studies of the tectal representation of the frog binocular visual field. A problem of methodology.

Using the classical mapping technique, the spatio-tectal visual organization in frogs (Rana esculenta) was investigated taking special interest in the previously described existence of a "systematic disparity" between the two monocular receptive fields of rostral binocular tectal points. The existence of such a disparity was extended to the whole binocular visual field and its sign (crossed or uncrossed disparity) was studied both in paralyzed and anesthetized animals. It was proved however that this disparity phenomenon was not "systematic", but depended mainly on the experimental methodology. Its physiological significance is discussed.

Animals↗

A possible neurophysiological basis for depth perception in frogs: existence of a horopter surface.

In frogs, multi-unit receptive fields (MURF) of rostral binocular tectal points (BTP) show a crossed disparity when mapped at a distance equal to the perimeter radius (i.e., 33 cm). The shape of the spatial surface where MURF of all BTP are in-register is investigated in two planes: (a) in the longitudinal plane, the locus of superimposition is a circumference passing through both eyes; (b) in the vertical plane, it corresponds to a straight line tilted towards the animal's head. This surface can be defined as the frog's horopter surface since it represents the spatial locus where objects can simultaneously stimulate corresponding retinal areas. Behavioural and electrophysiological correlations are discussed.

Animals↗

Pineal response types in the frog's brain under white light exposure.

Responses to white light stimulation can be recorded with electrophysiological methods at the level of (1) the pineal system (2) different diencephalic nuclei and (3) the mesencephalic tegmentum. The neurons are classified in six groups according to their discharge characteristics. As some responses present a higher complexity than the classical messages, an integration of the pineal informations during their course toward the brain is suggested in order to support phototactic behavior.

Animals↗

[Topography of the tecto-tectal component of the main ipsilateral visual pathway of the frog (Rana esculenta L.)].

The detailed topography of the tecto-tectal component of the Frog's ipsilateral visual pathway is electrophysiologically obtained by mapping the optic lobes. This linkage transfers the visual information explored along a transversal tectal row on to an homologous line oriented at 130 degrees on the opposite tectum. The ipsilateral projection of the temporo-nasal axis of the retina, but not of the antero-posterior axis of the visual field, is reversed compared to its contralateral projection. Finally, the majority of the homologous tectal points are asymmetrical with respect to the animal's sagittal axis.

Animals↗

Diencephalic binocular wide field neurons in the frog.

Single binocular neurons were recorded in the frog diencephalon (area dorsalis posterior and area ventralis thalami). These neurons respond to any moving stimulus from 1 degree 30 to 32 degrees in diameter, without directional selectivity and to an ON-OFF light stimulation. They are not activated by stationary objects. Habituation is also commonly observed. The most important feature of these neurons is their wide receptive field which covers the whole visual field of the frog. Evidence that these neurons receive inputs from each tectum is discussed.

Animals↗