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Biomedical subjects

F Gabrielli

Publications and source records attributed to F Gabrielli.

At least 73 records · Page 4Linked to original sources

[Results of periodic irrigation in rehabilitation of colostomy patients].

The Authors report their experience about 152 patients examined between 1976-1979 in the Aistom Centre of the Institute of "Semeiotica Chirurgica" at the University of Trieste. 98 patients irrigated their colostomies, while 57 patients were excluded in consequence of general or local counterindications. 92% of the irrigating patients gained fecal continence, but 1/4 of them use the colostomy bag to obtain full control of gas and odors. No cases of colonic perforation, bleeding or severe dermatitis were observed. The follow-up shows that most of the irrigating patients undergo less serious psychological problems and usually have easier social lives. It is opinion of the Authors that the results of colonic irrigation are better than natural evacuation. Irrigation should be therefore considered the best method of choice for the management of permanent colostomies.

Aged↗

[Clinical aspects and therapy of malignant neoplasms of the anal margin and canal].

The Authors, on the base of their experience by the Institutes of Surgical Semeiotics at the Trieste University and of Surgical Pathology at the Padua University, report 30 cases of malignant neoplasms of the anus and the anal canal. 17 patients were males and 13 females. Pathological, clinical and diagnostic problems are discussed. The Authors stress the value of surgical therapy, consisting in a simple local excision or in a wide abdominoperineal resection in conformity with the distinctive features of every single neoplasm. The surgical strategy against nodal metastases is proposed, and the results which are obtained by combining surgery and irradiation are analysed. It is opinion of the Authors that surgical therapy is the most suitable approach for radical treatment of these neoplasms, even if early experience with multimodality therapy is promising to be a great success.

Adenocarcinoma↗

[The use of rating scales for the study of diagnostic models: recognition of the uncertainties in classification principles].

In a cross cultural comparison of diagnostic concepts, we obtained from 45 expert italian psychiatrits symptom rating profiles, in terms of B.P.R.S., of the 12 most used diagnostic categories. While for 11 diagnostic concepts agreement was reasonably good, for cycloïd psychosis the variability of results supported the conclusion that this diagnostic concept is rather non specific among italian psychiatrists.

Cross-Cultural Comparison↗

Further evidence of transcriptional and translational control of histone messenger RNA during the HeLa S3 cycle.

Using a translational assay and new analytical procedures we have found that: -Histone mRNA can be detected both associated with polyribosomes and in the postribosomal supernatant of S phase HeLa S3 cells.-Inhibition of DNA replication by cytosine arabinoside treatment causes histone mRNA to completely disappear from polyribosomes, and little histone mRNA can be detected in the postribosomal supernatant of inhibited cells. These data indicate that histone mRNA does not accumulate in the cytoplasm after the inhibition of DNA replication. -Histone mRNA species cannot be detected in the postribosomal supernatant of G1 cells synchronized by selective detachment. This observation, together with the previous finding that histone mRNA is not present on G1 polyribosomes, is consistent with the idea of a transcriptional block in histone mRNA production and transport to the cytoplasm during G1.

Carbon Radioisotopes↗