Localizing 3H-GABA in nerve terminals of rat cerebral cortex by electron microscopic autoradiography.
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Aminobutyrates↗
Biomedical subjects
F E Bloom
Publications and source records attributed to F E Bloom.
Studies on norepinephrine-containing afferents to Purkinje cells of art cerebellum. I. Localization of the fibers and their synapses.
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Animals↗
Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis.
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Action Potentials↗
Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate.
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Adenine Nucleotides↗
Cyclic adenosine monophosphate and norepinephrine: effects on transmembrane properties of cerebellar Purkinje cells.
Electrical properties of Purkinje cells were recorded by intracellular microelectrode during extracellular electrophoretic application of gamma aminobutyrate, norepinephrine, cyclic adenosine monophosphate, and dibutyryl cyclic adenosine monophosphate. All these substances hyperpolarized Purkinje cells. Transmembrane resistance decreased during gamma aminobutyrate hyperpolarization. In contrast, norepinephrine and the cyclic nucleotides generally elevated resistance. These results show that cyclic nucleotides mimic the unique effects of norepinephrine on the bioelectric properties of neuronal membranes.
Adenine Nucleotides↗
The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells.
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Age Factors↗
Histochemical localization of brain succinic semialdehyde dehydrogenase--a -aminobutyric acid degradative enzyme.
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Aldehydes↗
Growth and development of sympathetic ganglion: maturation of transmitter enzymes and synapse formation in the mouse superior cervical ganglion.
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Acyltransferases↗
Possible function of monoamines as neurotransmitters.
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Acetylcholine↗
The effects of drugs on serotonergic nerve terminals.
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Animals↗
Granular vesicles as criteria for intracellular localization of monoamines.
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Animals↗
Fine structure of islet-cell innervation in the pancreas of normal and alloxan-treated rats.
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Alloxan↗
Cytochemical and physiological effects of 6-hydroxydopamine on periarteriolar nerves of frogs.
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Animals↗
Macromolecules in synaptic function.
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Acetylcholinesterase↗
Possible cyclic AMP-mediated adrenergic synapses to rat cerebellar Purkinje cells: combined structural, physiological, and pharmacological analyses.
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Animals↗
Acino-insular cells in normal rat pancreas.
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Animals↗
Norepinephrine concentrating mechanisms in sympathetic nerve trunks.
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Animals↗
Prostaglandins E1 and E2 antagonize norepinephrine effects on cerebellar purkinje cells: microelectrophoretic study.
In microelectrophoretic experiments, prostaglandins E(1) and E(2) antagonize the reduction in discharge rate of cerebellar Purkinje cells produced by norepinephrine. Slowing of discharge evoked by 3',5'-adenosine monophosphate or gamma aminobutyric acid is not antagonized. These data provide the first indication that endogenous prostaglandins may physiologically function to modulate central noradrenergic junctions.
Action Potentials↗