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Biomedical subjects

F C Blodi

Publications and source records attributed to F C Blodi.

At least 55 records · Page 3Linked to original sources

Giant cell (reparative) granuloma of the orbit.

Clinically and histologically, there exists considerable controversy as to what constitutes a giant cell tumor. There is an increasing awareness that the term giant cell tumors should not be used indiscriminately in describing lesions of the mandible, maxilla, and facial bones which contain multinucleated giant cells. This paper reports a rare case of giant cell reparative granuloma of the orbit. The differentiation between giant cell reparative granuloma and the true giant cell tumor is discussed and a description of the visual symptomatology associated with these lesions of th sphenoid bone is presented. These tumors must be removed completely to prevent recurrence.

Adolescent↗

[Changes in the retina accompanying the Osler syndrome (author's transl)].

A histological examination was carried out on the eye of an eleven-year-old patient who, like his brother, was suffering from the lung variety of the Osler syndrome. The examination showed rubeosis of the iris accompanied by secondary glaucoma. One striking feature was extensive proliferous retinopathy presumably caused by chronic lack of oxygen in the arterial blood.

Blindness↗

Ophthalmology.

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Diabetic Retinopathy↗

Eye problems of the elderly.

The most frequent changes of the anterior eye observed in senescence include changes in refraction which may be toward the hyperopic or the myopic side and a diminished tear secretion which may lead to the sicca syndrome. The corneal endothelium often shows degenerative changes which may lead to a decompensation of the cornea and corneal edema. A senile cataract is a frequent finding in older people as is chronic open angle glaucoma. One of the most serious senile changes in macular degeneration which may lead to extremely poor central vision though the peripheral vision may still be satisfactory. A similar effect has the less frequently seen anterior ischemic optic neuropathy.

Aged↗

Ophthalmology.

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Choroid Neoplasms↗

A clinicopathologic study of orbital and adnexal non-Hodgkin's lymphoma.

An analysis of non-Hodgkin's lymphoma involving the orbital structures was performed at the University of Iowa between 1937 and 1975. Sixteen cases of primary orbital lymphoma were diagnosed. Histopathologic reclassification according to the Rappaport scheme and the clinical course of each histologic sub-category was described. There were 5 patients with reactive hyperplasia, 2 patients with well-differentiated lymphoid proliferation with Dutcher bodies which were also felt to be reactive, 3 patients with diffuse poorly differentiated lymphocytic lymphoma, 4 patients with nodular poorly differentiated lymphocytic lymphoma, and 2 patients with diffuse histiocytic lymphoma. It was concluded that the Rappaport classification is applicable to orbital lymphoid tumors and that those lymphomas which do present as primary tumors should be staged as one would stage the same histologic category of lymphoma presenting in other sites. Radiation therapy appears to be an effective treatment for local control; however, patients with primary orbital lymphoma should undergo observation for systemic disease similar to patients with lymphoma presenting in other sites. Excisional biopsy is recommended to facilitate precise classification.

Aged↗

Localized conjunctival amyloidosis.

We treated a patient with localized amyloidosis of the bulbar conjunctiva, which strongly resembled a neoplastic growth. Although the patient suffered from a long-standing, debilitating rheumatoid arthritis, suggesting the possibility of a secondary systemic amyloidosis caused by the chronic effusive process, no specific clinical evidence of systemic amyloidosis was noted. The ocular lesion was, therefore, classified as a primary localized amyloidosis. However, the simple recognition of amyloid in the ocular adnexa should not be considered a complete diagnosis. For such cases in which a prominent underlying systemic disease is present, a thorough medical evaluation and future follow-up should be ensured to rule out the possibility that this represents the initial manifestation of a potentially life-threatening secondary systemic amyloidosis caused by rheumatoid arthritis.

Aged↗