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Biomedical subjects

F C Blodi

Publications and source records attributed to F C Blodi.

At least 73 records · Page 4Linked to original sources
PubMed1978

Ophthalmology.

Explore the source record for details and available documents.

Diabetic Retinopathy↗
PubMed1978

Peripapillary choroidal melanomas. Extension along the optic nerve and its sheaths.

We reviewed 26 cases of peripapillary melanoma, 21 (80.8%) of which extended into the optic nerve or its meningeal sheaths. Most melanomas that extended into the optic nerve were necrotic and of the mixed or epithelioid cell type; all invaded the overlying retina and occurred in blind eyes with secondary glaucoma. The extension of melanoma cells into the subarachnoidal space was only influenced by the presence of the melanoma around the optic nerve head (peripapillary). The prognosis of these patients was highly dependent on the presence of orbital extension. A long piece of optic nerve should be excised when eyes with peripapillary melanomas are enucleated.

Choroid Neoplasms↗
PubMed1977

Prognostic factors in choroidal and ciliary body melanomas.

We reviewed 293 cases of choroidal and ciliary body melanoma with a followup period of five years or more. Nine factors influenced significantly the prognosis: Age of the patient at the time of enucleation, location of the tumor and of its anterior border, largest tumor diameter in contact with the sclera, height of the tumor, integrity of the Bruch membrane, cell type, pigmentation, and scleral infiltration by tumor cells. Some of these factors can be evaluated clinically before the enucleation. Seven sets of three factors each were determined in order to have better prognostic values based on the clinical data and the cell type. The largest tumor diameter is the single most important clinical and pathological prognostic factor. The prognosis is relatively good when this diameter is 10 mm or less and becomes poor when it exceeds 10mm.

Adolescent↗
PubMed1977

Orbital extension of Choroidal and ciliary body melanomas.

In a review of 432 choroidal and ciliary body melanomas, histopathologic evidence of orbital extension was found in 45 cases (10.4 percent). The occurrence of orbital extension was influenced mainly by the cell type (P less than .05) and by the size of the choroidal mass (P less than .001). Local orbital recurrence occurred in 23 percent of cases with evidence of extrascleral extension. Survival rates were independent of cell type, pigmentation, and size and shape of the extension. Patients treated by exenteration had significantly better prognosis than nontreated patients or patients treated by chemotherapy, radiotherapy, or local excision (P equals .0002). Early exentration is the best treatment for choroidal melanomas with orbital extension.

Choroid Neoplasms↗
PubMed1977

[Orbital pseudotumor with thrombocytopenia and myasthenia (author's transl)].

A 13-year-old girl presented first with an inflammatory pseudotumor of the orbit. A biopsy showed lymphoid hyperplasia. A few months later the patient developed an idiopathic thrombocytopenia. Six months later she developed a myasthenia. The latter responded well to a thymectomy and the orbital pseudotumor disappeared with radiotherapy. The possible connection among these three diseases is discussed.

Adolescent↗
PubMed1977

[A dirofilaria granulom of the lid and the orbid (author's transl)].

A 66-year-old woman of the northeastern USA developed suddenly a tumefaction of the lid and the orbit. After the excision a granuloma was found which was caused by a dirofilaria conjunctivae. This worm occurs in North-America mainly in racoons and is transmitted to humans by a fly or a mosquito. This infestion is usually found in the warm zones. Our case is an exceptional one as it occurred in the temparate zone.

Aged↗
PubMed1976

Pathology of orbital bones. The XXXII Edward Jackson Memorial Lecture.

The orbital bones may show nearly all the pathologic changes observed in the skull and in the face. The congenital anomalies in this area are numerous and involve various forms of craniostenoses. Among the benign osseous tumors the osteoma is most frequently encountered in the orbit. Fibrous dysplasia is a tumefaction of indeterminate behavior that often involves the orbit. Osteosarcoma or other malignant neoplasms are rarely seen in this area. Eosinophilic granuloma and Hand-Schüller-Christian disease are tumor-like lesions that may involve the orbit.

Bone Cysts↗