Search PubMed⌕ Search

Biomedical subjects

E Zeitler

Publications and source records attributed to E Zeitler.

At least 91 records · Page 5Linked to original sources
PubMed1984

Electron imaging of crotoxin complex thin crystal at 3.5 A.

Crotoxin complex forms thin crystals which are suitable for electron crystallographic analysis. We have used a 100 kV electron microscope equipped with a superconducting lens to image this crystal embedded in glucose. Optical diffraction analysis of the micrographs show unambiguously a structural resolution of 3.9 A which has not been obtained with the conventional microscope at room temperature. A density map with a nominal resolution of 3.5 A has been synthesized from these images by computer processing techniques.

Animals↗
PubMed1984

Time-resolved low-dose microscopy of glutamine synthetase molecules.

Time sequences of low-exposure images from the enzyme molecules of glutamine synthetase have been recorded digitally using an on-line recording system. Processing the images results in a time sequence of averaged molecule images, which, in the very beginning, exhibit the molecule structure still undamaged by electron irradiation. Different sources of the noise which obscures structural details, such as shot noise, stain embedding and radiation damage, are investigated.

Glutamate-Ammonia Ligase↗
PubMed1984

[ECG-triggered NMR tomography of the heart].

The technique and scope of ECG-triggered NMR tomography of the heart are described. Correct attachment of the ECG electrodes and cables is important in order to avoid artifacts. The anatomical structure of the heart and mediastinum can be demonstrated with a clarity which has not been possible hitherto in all three planes (axial, frontal, sagittal). This results in considerable advantages when examining abnormal hearts, since it is possible to avoid the risk of contrast media.

Electrocardiography↗
PubMed1984

[Digital-subtracted magnetic resonance (DSMR). A new procedure for improved imaging of vascular processes].

Using varying echo-sequences, NMR studies of flow in vessels shows varying signal relationships which are caused by intermittent re-focussing of the elementary magnetic particles. By means of digital subtraction of the tomograms, this effect can be clearly shown. It has been demonstrated that this particular procedure can be used for improved visualisation of vessels and of abnormal vascular processes (thrombosis, tumours, aneurysms etc.).

Aged↗
PubMed1984

[Present status of digital subtraction angiography].

The present state of development of digital subtraction angiography can be characterised by the fact that, according to the results obtained so far, it can be most useful as a diagnostic method, depending on the clinical problems involved and on the condition of the patient, taking into consideration any possible history of patient allergy and the state of his cardiac and renal functions; if there are no contra-indications, the requisite contrast medium can be applied intravenously or intra-arterially. This method can also be used as a complement to conventional large-format angiography to obtain additional information; in other cases, it may not supply information in sufficient detail, thus requiring subsequent large-format angiography. Diagnostic safety of this method is more than 95% in all the essential indications, such as diagnosis of extracranial cerebrovascular disturbances of blood flow, detection of aneurysms of the aorta, evaluation of postoperative and post-treatment conditions in the vascular system, as well as renovascular hypertension. However, an essential prerequisite is the appropriate use of technical aids fitted to the equipment used for examination. Other essential requirements are the best possible positioning of the patient and his ability to cooperate.

Analog-Digital Conversion↗
PubMed1983

Efficacy and safety of digital subtraction angiography with special reference to contrast agents.

We evaluated the diagnostic accuracy and complications of digital subtraction angiography (DSA) in a series of clinical trials conducted on patients primarily with cerebral vascular disease and those evaluated before and after surgery or percutaneous transluminal angioplasty. Double-blind studies of the carotid-vertebral arteries of 300 of the 2,200 patients using DSA imaging and a variety of ionic and nonionic contrast agents showed that although subjects tolerated the injection of nonionic contrast better than ionic, nonionic contrast administration did not lead to better image quality. Of 764 patients receiving ionic contrast media, 3.3% had mild-to-serve adverse reactions; of 350 injected with nonionic contrast agents, 1.7% had mild-to-severe adverse reactions. If the sole consideration is safety, use of ionic contrast media is justified.

Angiography↗
PubMed1983

[Radiation exposure of the population from examination of the thoracic organs].

The radiographic examination of the lung is still the most frequently carried out radiodiagnostic procedure, and--as explained--will remain so in future, too. The article reports on the significance that the examination of the lung has for the x-ray exposure of the population, the body surface dose, the bone marrow dose, the effective dose equivalent, and the energy absorbed being the measure for the exposure. The considerable variation of the absorbed doses dependent on the different x-ray systems and the effect of new techniques (large screen intensifiers) are described.

Europe↗
PubMed1983

[Special complications in leg phlebography].

Some rare, but serious, complications during leg and pelvic phlebography are described. One fatal pulmonary embolus and six cases of necrosis of the dorsum of the foot due to phlebography were encountered. The causes, pathogenetic factors and other possible complications are discussed. Extravasation of contrast due to puncture on the lateral side of the foot, or near the ankle joint, leads to the formation of a contrast bleb which may proceed to tissue necrosis.

Adult↗
PubMed1983

Results of percutaneous transluminal angioplasty.

Percutaneous transluminal angioplasty (Dotter technique) was used in 2,942 cases of iliofemoral atheromatous disease. Results varied with the characteristics of the obstructing lesion (length and location) and the clinical stage of ischemia (claudication, rest pain, gangrene). Based on the foregoing, angioplasty is done either as the preferred primary treatment or for the relief of clinically advanced disease in patients unsuitable for high risk surgery. Success is favored by the use of aggregation inhibitors and single-use Teflon or balloon catheters; complications are few.

Aged↗
PubMed1982

New technical trends in coronary laboratories.

Increasing experience and improvement of the techniques used in coronary angiography and left ventriculography, have advanced patient safety and the proper assessment of coronary heart disease. High-resolution image intensifiers, coupled with the use of 50 or 25 frames-per-second cinematography or 100 mm spot film technique, offer diverse possibilities for optimal documentation of the morphologic findings. For an evaluation of both hemodynamics and cinematography, computer-assisted units increasingly simplify work and offer greater safety in procedures that assess ventricular function.

Angiography↗