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Biomedical subjects

E Schmidt

Publications and source records attributed to E Schmidt.

At least 271 records · Page 15Linked to original sources
PubMed1982

Improved degradation of monochlorophenols by a constructed strain.

Pseudomonas sp. strain B13, a strain able to degrade 3-chlorobenzoate and, after prolonged adaptation (40 days), 4-chlorophenol, could transfer the ability to degrade chlorocatechols to a recipient, Alcaligenes sp. strain A7, which is able to grow with benzoate and phenol. Representative transconjugants, such as Alcaligenes sp. strain A7-2, were able to utilize all three isomeric chlorophenols; this property was not possessed by the donor or the recipient. The ability to grow readily with 4-chlorophenol may be attributable to a more rapid induction of phenol hydroxylase by Alcaligenes sp. strain A7-2 than by Pseudomonas sp. strain B13, a property which correlates with the greater level of resistance to chlorophenols shown by the transconjugant.

Journal Article↗
PubMed1982

Effect of pancreas transplantation on liver carbohydrate metabolism in streptozotocin diabetic rats.

The failure of pancreas transplantation to normalize plasma glucagon concentration and insulin: glucagon balance in portal blood has recently been demonstrated on streptozotocin-diabetic rats. The same experimental model was used in the present study to examine the effect of pancreas transplantation on liver carbohydrate metabolism. Twenty weeks after pancreas transplantation, the left hepatic lobe was removed for studies of several glycolytic and gluconeogenic enzymes. Livers from nontransplanted diabetic rats showed decreased activities of glycolytic enzymes and enhanced activities of gluconeogenic enzymes. In recipients of pancreas transplants, however, the activities of glycolytic and gluconeogenic enzymes did not differ from those observed in normal control rats. It is concluded that the alterations of hepatic gluconeogenesis and glycolysis observed in streptozotocin-diabetic rats are restored to normal by the pancreas transplant despite its failure to obviate hyperglucagonaemia.

Animals↗
PubMed1982

[Predisposed connections of chronic oropharyngitis and chronic otitis media respectively the endocrinium of menopause (author's transl)].

Eventual predisposed clinical connections of chronic oropharyngitis and otitis media chronica respectively of serum levels of menopausal hormones are examined by clinical-statistic methods or laboratory diagnostics (ratio-immunoessay). Statistic means point out that 71% of all patients suffering from chronic otitis media show symptoms of chronic oropharyngitis too. The question of connection naturally cannot be cleared up as a demonstration, but nevertheless predisposition seems to be probable. Hormonal influence in female during menopause seems not to be predisposing in pathogenesis of oropharyngitis seen very often in this age. This is shown by normal serum levels of oestradiol, FSH and LH in 30 women with chronic oropharyngitis.

Aged↗
PubMed1982

[Microangiographic studies on the revascularization of free smooth muscle grafts].

The aim of the investigations was to find out exactly how and when revascularization of free transplanted smooth muscle took place. For this purpose a continent colostomy was performed on 15 dogs by sphincter plastics with a free autologous transplant. The dogs were killed between postoperative day 1 and 5, and their blood vessels were perfused with mixture of Indian ink and Ringers solution. The microangiographic observations of the microscopic section showed the following results. On postoperative day 1 at the edge of the transplant the vessels of the intestinal serosa were distinctly seen to have ellipsoid dilatation. On day 2 tiny filamentary branches of the vessels proliferated into the transplant and connected with the original vessels of the sphincter plastic. By days 4 and 5 this process was apparent.

Angiography↗
PubMed1981

[Plastic surgery for sphincter continence (author's transl)].

Free transplanted intestinal smooth muscle was used for plastic surgery of the sphincter in 137 patients. In 113 patients closure and continence were possible so that a colostomy bag could be avoided. The continence rate was thus 82.5%. Slight parastomal infection occurred in 15 patients. However, this did not affect continence.

Adolescent↗
PubMed1981

The Weaver syndrome: a rare type of primordial overgrowth.

A boy with primordial overgrowth, macrocephaly, and anomalies of the face, nails, feet and skeleton is reported. Two cases in the literature- referred to as Weaver syndrome- exhibited nearly identical anomalies. All three cases were sporadic. Main symptoms of the Weaver syndrome are increased birth weight, early overgrowth, macrocephaly, accelerated osseous maturation, typical facies, hoarse, low pitched voice, hypertonia of muscles and mild developmental delay. Further symptoms are thin, deep-set nails, talipes equinovarus, widened distal femora, and some minor abnormalities. A second boy with primordial overgrowth and macrocephaly demonstrated some, but not all, the symptoms of this syndrome. Whether this boy showed a milder expression of the Weaver syndrome or benign familial macrocephaly is discussed.

Abnormalities, Multiple↗