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Biomedical subjects

E Lang

Publications and source records attributed to E Lang.

At least 199 records · Page 11Linked to original sources
PubMed1977

[Relationship between a state of sleep and wakefulness and transmission of an afferent signal through the posterior ventral nucleus of the thalamus].

Chronic experiments were carried out on nonanesthetized cats. A study was made of peculiarities attending the transmission of the afferent signals and the following inhibitory processes in the posterior ventral nucleus of the thalamus, depending on the state of sleep and wakefulness. Transmission of the signals decreases during the dreaming condition and the slow-wave sleep, and increases during the active states of alert cats. In paradoxical sleep the signal transmission is at the same level as such at resting wakeful condition. A marked transmission fluctuation is seen during the dreaming state and in the course of the first phase of sleep. The level of signal transmission is the most stable during the active states. The degree of the trance inhibitory process after the afferent signal transmission depends on the level of anesthesia, wakefulness and natural sleep. Processes following the afferent signal transmission in the posterior ventral nucleus of the thalamus show a radical difference in the barbituiate-anesthetized in comparison with nonanesthetized animals. The trace inhibition, so characteristic of anesthesia, was expressed in the dreaming state of the animal but insignificantly; in the wakeful condition it is not manifested at all.

Anesthesia, General↗
PubMed1977

[Practice in infusion therapy and parenteral feeding].

Today, the steadily growing selection of industrially produced infusion and nutritive solutions can hardly be overlooked by the clinician. It is therefore most important for him to limit himself to a number of modern, clinically approved solutions whose composition, maximal infusion rate, indications, contra-indications and side-effects are well known to him. Moreover, a successful infusion therapy and parenteral nutrition postulate the mastery of modern infusion techniques.

Acid-Base Imbalance↗
PubMed1977

[The geriatric patient and his nutrition].

The nutrition of geriatric patients should observe the following characteristics of advanced age: diminished calorie requirement, impaired glucose tolerance, tendency to elevated serum cholesterin and triglyceride levels, increased requirements for protein of high biological value, absence of thirst and reduced total body water. Considering these metabolic changes recommendations for an adequate nutrition of senescent people are discussed.

Adult↗
PubMed1977

[Systolic periods in dependence of age].

In 278 healthy probands in the age of 23 to 80 years were measured the systolic periods and examined in dependence of age. There are found the following results: 1. from the youngest to the oldest group there is a small, statistically not significant increase of the middle systolic period. 2. the presphygmic phase (PEP) and the frequence-corrected interval (PEPI) show a small increase of the middle values in the first four age steps. Only after the age of 60 years is a clear increase of PEP and PEPI. 3. the expulsion time (LVET) and the expulsion index (LVETI) show in an increasing tendency of the mean values no significant difference of the mean value in the age groups. 4. the quotient LVET/PEP follows the course of PEP and PEPI. There is supposed, that the clear statistically significant increase of the mean value of the presphygmic phase and the presphygmic index after the age of 60 years cannot not be reduced to a "physiologic age insufficiency of the heart", but its cause is founded in asymptomatic courses of the coronary heart disease or other defined heart diseases.

Adult↗
PubMed1977

[Electron-autoradiographic analysis of projections of somatosensory cortex regions I and II to the posterior ventral nucleus of the thalamus].

To reveal the differences in the nucleus ventralis postero-lateralis (VPL) of the thalamus of the corticofugal fibers originating from the first (S1) and the second (S2) somatosensory areas a combined morphological study was undertaken using autoradiography and electron microscopy of the degenerating terminals. Within the range of VPL distribution of the cortico-fugal fibers of the corresponding zones of two cortical somatosensory regions differed from one another. The terminals of both types of the fibers established synaptic contacts, chiefly with the distal dendrites of the relay VPL cells, and much more rarely with the dendrites of the interneurons of the Golgi II type. No direct convergence of the fibers originating from two somatosensory regions on single VPL elements was observed.

Animals↗
PubMed1977

[The resonance frequency of the radial artery in healthy untrained and endurance-trained older men].

There are examined 2 groups of two at a time men over 55 years old, different only in their training state, regarding the reaction of the resonance frequence. It would be established, that the resonance frequence of the A. radials in non-trained is more than the double as in trained probands. The middle resonance frequence increases continuous with the age in both groups. A high resonance frequence in thong-minded trained was not observed, only one time a normal, 63 times a reduced arterial resonance frequence. Under the condition, that the arterial resonance frequence can be regarded as an arterial index, the differences between the resonance frequence of both groups mean, that the biological age of the arteries in trained is on an average younger as in non-trained.

Aging↗
PubMed1976

[Coronary angiographic findings in dextrocardia (author's transl)].

This paper reports on four different types of dextrocardia in situs solitus and situs inversus. The topography of the atrial and ventricular cavities, of the great vessels and of the coronary arteries is described in detail. The value of the selective coronary arteriography in differentiation between the types of dextrocardia is discussed.

Adult↗
PubMed1976

[Stress and electrocardiogram. Telemetric investigations during a stunt flight program (author's transl)].

The excitation process in the electrocardiogram was telemetrically transmitted and recorded during psychic stress of 25 subjects aged between 17 and 56 years with healthy cardiovascular systems, during a standardized stunt flight program. The pulse rate profile showed a clearly marked sinus arrhythmia in the prestart phase and during the flight figures in which no acceleration force is in action, but essentially psychic stress alone. Corresponding to this sinus arrhythmia are distinct changes in amplitude of the P and T waves and the duration of the PQ interval, comparable to a changing sympathetic or vagus ECG. The behavior of the ST segment corresponds to that of ergometric stress, a horizontal or descending lower course was also observed in the younger subjects. In one case a 2:1 parasystole was observed during the change-over phase from higher to lower heart rates.

Adolescent↗
PubMed1976

[Orthostatic hypotension in the aged].

Caird and his colleagues reported posture-dependent falls in systolic blood pressure of 20 mm Hg and more in 24% of a population aged 65 and above. In about 5% of the group, moreover, the falls were in excess of 40 mm Hg. Our investigations in 160 residents in an old people's home in the age range 59-88 years largely confirmed Caird's figures. Using Schellong's test we recorded systolic pressure falls of 20 mm Hg and more in 25% of our subjects. These cases of circulatory dysregulation were all manifestations of the hypodynamic form of the orthostatic syndrome. This means that only systolic blood pressure fell, diastolic pressure as well as heart rate being largely unaffected. The phenomenon appears to be due to age-related deterioration in circulatory regulation; at least no evidence has been found to suggest that it has a specific aetiology. In a double-blind cross-over study the effect of dihydroergotamine (DHE) was compared to placebo in 40 patients. Half the patients were given 2 mg DHE three times daily for 14 days and the other half placebo tablets; following 1 week's wash-out, the treatments were then reversed for a further 2-week period. Schellong's test (measurement of blood pressure and pulse after 10 min in the supine position and then after 1, 2, 5 and 10 min standing) was performed at the beginning and end of each treatment period. The average falls in upright systolic pressure for all 40 patients were as follows: before treatment 20 mm Hg (150 leads to 130); end of placebo period 19 mm Hg (147 leads to 128); end of DHE periods 7 mm Hg (145 leads to 138). The differences between the values recorded after treatment with DHE and the other two values are statistically significant (p less than 0.05). Similarly there was a significant difference in the numbers of patients experiencing dizziness during Schellong's test (16-17 out of 40 patients before treatment and after placebo, 6 out of 38 patients after DHE). From this finding conclusions can be drawn regarding the causes of vertigo in old age.

Age Factors↗
PubMed1976

[Autosomal dominant hereditary atrial septal defect with heart conduction defects and mitral valve insufficiency].

An autosomal dominant inherited ASD with conduction defects in one family is described. 6 members of 4 generations were fallen ill. In 4 patients the diagnosis was made clinically, in 2 sisters the diagnosis was confirmed by operation. Moreover, the last 2 patients had a mitral insufficiency--probably congenital. The ecg-findings of 4 patients additionally showed conduction defects in form of AV-and bundle branch blocks.

Adult↗
PubMed1976

[Influence of the somatic region of the cortex on trace inhibitory processes in the posterior lateral nucleus of the thalamus].

Acute experiments were conducted on cats under nembutal anesthesia. A study was made of the dynamics of the changes occurring in the curve of restoration of the test response amplitude in the thalamo-cortical fibers to the pared stimulation of the medial lemniscus with various actions on the somatosensory ared. The curve under study served as an indicator of the corticofugal influences on the inhibitory after process in the transmission nucleus of the thalamus. The influences on one somatosensory area of the cortex blocked the transmission of the afferent signals in 70% of the neurons of the transmission nucleus of the thalamus. A correlation between the number of the neurons participating in the reaction and the character of the initial phase of the inhibitory afterprocess was noted.

Animals↗
PubMed1976

[D-transposition in situs inversus, atrial septal defect, open foramen ovale and tricuspid valve insufficiency].

This paper reports on a rare case of a so-called corrected d-transposition of the great vessels of a 62-year old woman with situs inversus. In addition the patient had a VSD, a patent foramen ovale, and a tricuspid-valve insufficiency. The topography of the ventricular cavities, the great vessels and the coronary arteries is described in detail. There is pointed to the surgical treatment of additional abnormalities to improve the prognosis.

Electrocardiography↗