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Biomedical subjects

E Burgos

Publications and source records attributed to E Burgos.

At least 37 records · Page 2Linked to original sources
PubMed1994

Calcified leiomyoma of deep soft tissue. Report of a case in childhood.

This report illustrates a calcified leiomyoma of deep soft tissue in the left leg of a 6-year-old boy. The tumour was composed of spindle cells arranged in interlacing bundles, between which were multiple small and large areas of calcification. Tumour cells were positive for vimentin, desmin and smooth muscle actin. Ultrastructurally, the cells showed numerous pinocytotic vesicles and bundles of intracytoplasmic filaments with smooth muscle dense bodies. Only four calcified leiomyomas have been previously reported in the deep soft tissues of limbs. Here we report a new case and suggest a new pathogenetic scheme involving alkaline phosphatase in the origin of these calcifications.

Calcinosis↗
PubMed1993

Signet-ring stromal tumor of the ovary: a histochemical, immunohistochemical and ultrastructural study.

We report a signet-ring stromal tumour found in the ovary of a 50-year-old woman. The solid tumour was composed of spindle and round cells which stained with vimentin and some round cells were vacuolated and had the appearance of signet-ring cells. The vacuoles were negative with periodic acid-Schiff, with and without diastase digestion, with alcian blue, Sudan III, alpha-1-antitrypsin and alpha-fetoprotein stains. Ultrastructurally, they were membrane bound and contained scantly flocculent material. Some neoplastic cells contained intracytoplasmic eosinophilic globules which were positive with alpha-1-antitrypsin. Signet-ring stromal tumour is a benign, morphologically distinctive type of ovarian stromal tumour, which may present problems in differential diagnosis with other stromal and non stromal ovarian neoplasms.

Adenocarcinoma, Mucinous↗
PubMed1992

Failure to detect unique reactivity to streptococcal streptokinase in either the sera or renal biopsy specimens of patients with acute poststreptococcal glomerulonephritis.

Using purified group A streptokinase (SKA) as the antigen, ELISA assays were carried out on the sera of normal unaffected children, acute poststreptococcal glomerulonephritis patients (APSGN) and acute rheumatic fever patients (ARF). The results demonstrate that antibody titers to SKA increase with age in normal children and by age 8 years the vast majority of children have antibodies to SKA. APSGN patients did not demonstrate unique reactivity to SKA when compared to ARF patients either at time of onset of disease or during convalescence. Polyclonal and monoclonal antibodies to SKA which recognize both group A and C streptokinase failed to detect the presence of streptokinase in the biopsy sections obtained from ten well-documented APSGN patients. We conclude that there is no unique reactivity to group A streptokinase in the sera of APSGN patients. Furthermore, we failed to demonstrate the presence of streptokinase in the biopsy specimens of an early case of APSGN patients.

Adolescent↗
PubMed1991

[The association of myasthenia gravis and hairy-cell leukemia].

Myasthenia gravis (MG) and tricholeucemia (TL) produce an important immune alteration favoring the appearance of neoplastic and autoimmune disorders. The case of a 53 years old patient who developed type B TL 5 years after the diagnosis of MG is reported. Upon revision of the literature, 37 cases of association of MG and malignant hemopathies, fundamentally lymphoproliferative were found. In general, MG precedes the appearance of the neoplastic process. The autoimmunity and immunodeficiency characteristic of MG probably constitute the pathogenic mechanism leading to the appearance of the neoplastic process.

Bone Marrow↗
PubMed1990

Hairy leucoplakia--a clinical, histopathological and ultrastructural study in 33 patients.

Thirty-three cases of hairy leucoplakia (HL) in HIV-positive patients were studied. The most frequent clinical presentation was the development of corrugated plaques on the lateral sides of the tongue without spiculations on the surface. In all biopsies, herpetic-type viral inclusions were found. In 12 out of 14 cases in whom an electromicroscopic study was carried out, only viral particles of the herpes group were found. Human papillomavirus (HPV) was not demonstrated, although by means of immunohistochemistry, positive labelling for HPV was found in 95% of the cases. The aetiopathological significance of these findings remains to be evaluated.

Adult↗
PubMed1990

Multiple self-healing indeterminate cell lesions of the skin in an adult.

We report a case of multiple cutaneous indeterminate cell proliferative lesions in an adult without any other organ involvement. All lesions regressed spontaneously over 5 years without recurrence over a 4-year period of follow-up. The electron-microscopic and immunohistochemical features of the cellular infiltrate were those of the indeterminate cells. This case supports the hypothesis that indeterminate cell proliferative disorder is a wide spectrum of conditions with variegated clinicopathologic presentation and with different biological behavior.

Cell Line↗
PubMed1988

Malignant rhabdoid tumor of the tongue. A case report with immunohistochemical and ultrastructural findings.

An extrarenal malignant rhabdoid tumor of the tongue in a 10-day-old boy is described. The tumor produced severe respiratory distress and had an aggressive clinical course. The patient died 17 days after the initial diagnosis. The tumor was mostly composed of poorly differentiated, round, polygonal or elongated cells. Ultrastructural examination showed intracytoplasmic filamentous inclusions in many of the cells. The cytoplasm was diffusely positive to anti-vimentin antibodies with focal, scarce positivity to anti-keratin antibodies. To the best of our knowledge, this is the first reported case of malignant rhabdoid tumor of the oral cavity.

Cell Nucleus↗
PubMed1987

Hemangiopericytoma of the trachea.

Malignant neoplasms of the trachea are rare lesions, with no more than 400 cases documented in the literature. Only three tracheal hemangiopericytomas have been reported. We present the fourth case of such a tumour occurring in the trachea. After the first surgical resection the tumour recurred twice in a period of 10 months. The last cervicotomy performed for local recurrence showed wide cervical and mediastinal involvement of the tumour, not resectable surgically. Emphasis is placed on the surgical, pathologic and ultramicroscopic findings.

Biopsy↗