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Biomedical subjects

E Belgrano

Publications and source records attributed to E Belgrano.

At least 91 records · Page 5Linked to original sources

Microsurgical one-stage repair of hypospadias with a rectangular transverse dorsal preputial vascularized skin flap.

A microsurgical technique for one-stage repair of hypospadias using a rectangular transverse dorsal preputial island skin flap is presented. The use of optical magnification, atraumatic technique, and microsurgical instruments allows a vascularized preputial skin flap to be raised and isolated on the dorsum of the penis and then rotated ventrally and tubulized into a neourethral channel. The meatus of the new urethral channel lies at the tip of the glans. Cover for the penis is simply obtained and does not require a longitudinal row of sutures. The need to remove the distal stenotic portion of the urethra and to correct any degree of chordee is outlined and emphasized. Good cosmetic and functional results demonstrate the efficacy of such a technique.

Child↗

Temporary embolization in urological practice: myth or reality?

Clot embolization through percutaneous transcatheter technique has proved to be a highly effective and reliable method for stopping bleeding from renal or pelvic areas. The recanalization of the embolized vessels is constant and the recovery of the renal function quite satisfactory. In case of priapism temporary embolization may be very useful in selected cases.

Adolescent↗

PTH radioimmunoassay and loading tests in the diagnosis of patients with primary hyperparathyroidism.

PTH radioimmunoassay today represents an unreplaceable tool in the diagnosis of primary hyperparathyroidism. However, the diagnostic importance of its dosage on selective venous samples is still discussed. Herein, we report our experience of 47 patients operated on for primary hyperparathyroidism. The catheterization of neck veins was performed according to Doppman and co-workers. The PTH assay was carried out with COOH- and NH2-specific antisera. (In 5 cases an inhibition test with CaCl2 infusion was practiced during selective catheterization to preoperatively discriminate between adenoma and hyperplasia.) In 8 cases loading tests with EDTA and in 6 cases with CaCl2 were also performed in association with peripheral venous sampling, in an attempt to improve its sensibility. The 47 cases operated upon showed the following results: the peripheral PTH values were significantly raised in 60% of the cases; the selective PTH dosage with COOH-specific antiserum showed a parathyroid hyperfunction in 100% of the surgically confirmed cases, whereas with the NH2-specific antiserum an increased PTH rate was found only in 84%. A right preoperative localization was obtained in 73%. The value of loading tests is more difficult to evaluate and is discussed in detail.

Adult↗

[Parathyroid gland autotransplantation: long-term results and direct test of the function of the implant by selective parathyroid hormone determination and stress test].

The precision of PTH measurement and the location of the implant allow the functioning of the transplanted tissue to be easily checked by separately measuring the PTH concentration in the arm bearing the transplant in comparison with the other side. In 10 of the 13 patients operated on by us it was observed that the transplant had grown and was functioning satisfactorily. In 2 further patients, in whom the PTH concentration alone gave no clear information on the functioning of the transplanted tissue, the tolerance test was for this purpose decisive. In fact the transplanted parathyroid tissue showed a rapid and clear response to pharmacodynamic stimulus, which demonstrated the viability of the transplant. We therefore venture to say that pharmacodynamic investigation is of a certain use in postoperative examinations of these patients, especially in doubtful cases. Unfortunately we have had no opportunity to perform a histological investigation of the implanted endocrine tissue, but this has already been reported on in print.

Adult↗

Long-term results with autogenous microvascular grafts in various experimental models in rats.

Autogenous arterial and venous grafts were used to bridge defects in the femoral arteries, aortas, and renal arteries of 40 Wistar rats in an effort to determine the feasibility of using such grafts in the treatment of renovascular hypertension. The long-term results indicated that arterial grafts would be the most suitable in such a situation, but further study is needed before the technique can be applied clinically.

Animals↗

Usefulness of preoperative transcatheter embolization in kidney tumors.

In recent years preoperative transcatheter embolization has been used widely in the management of kidney tumors. However, the effective clinical usefulness of this method has not yet been proved. Forty cases of kidney tumors treated by preoperative embolization and radical nephrectomy are reviewed and compared with a homogeneous group of patients who did not undergo preoperative embolization. Intraoperative blood loss, postoperative complication, and survival rate were statistically evaluated according to tumor stage. Advantages and disadvantages of preoperative transcatheter embolization of kidney tumors are reviewed.

Adenocarcinoma↗

Infrarenal cavectomy and microsurgical reconstruction of an accidentally sectioned aberrant renal vessel in a patient with renal cell carcinoma.

A case of renal cell carcinoma invading the surrounding organs and extending into the infrarenal vena cava, treated by enlarged nephrectomy, splenectomy, resection of the diaphragm and extended resection of vena cava, is presented. Special attention is paid to the diagnostic angiographic approach, to the surgical solution adopted and to the microvascular reconstruction of an injured aberrant vessel of the contralateral kidney.

Adenocarcinoma↗

Surgical hyperparathyroidism in calcium stone formers. A retrospective study of 20 cases.

Urinary lithiasis, hypercalciuria and hyperparathyroidism are strictly related diseases, and the urologist diagnoses primary hyperparathyroidism (PHP) in the majority of cases. Herein we retrospectively analyze our experience of 20 cases of surgically proved PHP, operated on in the last 4 years. Hypercalcemia was the keystone for the diagnosis of all our cases PTH radioimmunoassay on selectivity sampled blood revealed a fundamental tool in the management of patients with suspicious or certain hyperparathyroidism. It confirmed the diagnosis in all the cases and gave the preoperative localization of parathyroid adenomas in 70% of the cases. Besides, it made it possible to discriminate between parathyroid adenomas and diffuse hyperplasia preoperatively, so offering a considerable aid to the surgeon in deciding between the conservative and liberal approach to parathyroid surgery. At follow-up, 3 out of 14 cases revealed renal hypercalciuria, which could have been the cause of hyperparathyroidism, as proposed by Reiss and associates previously. The relationship between hypercalciuria and hyperparathyroidism and the problem of a new classification of parathyroid hyperfunction are discussed.

Adenoma↗

Parathyroid autotransplantation.

7 patients with diffuse parathyroid hyperplasia underwent total parathyroidectomy and microsurgical autotransplantation for diffuse parathyroid hyperplasia. 5 of 7 patients showed good function of the grafted parathyroid tissue, as checked by the separate PTH assay from the grafted versus not grafted forearm. In 1 patient parathyroid stimulation test with EDTA infusion and suppression test with calcium infusion were also performed.

Adult↗

[Testis autotransplantation in the abdominal cryptorchidism (author's transl)].

Testis autotransplantation represents an elegant and safe surgical procedure in the complex problem of the abdominal cryptorchidism. The authors report 2 cases of testis autotransplantation, in a child and in a young adult. the technique is strictly microsurgical, using the operative microscope, the microsurgical instruments and microsutures. For the control, the use of Doppler sound has proven its efficacy. The first results are encouraging and the authors conclude that such an intervention deserves to be taken into consideration when the decision to conserve an abdominal testicle is considered.

Adult↗

[Brisk postoperative bleeding in a solitary kidney successfully treated by temporary clot embolization (author's transl)].

The so called temporary embolization by percutaneous injection of autologous clot can be envisaged as the method of choice in selected cases of massive renal bleeding. The goals of this technique are to occlude the bleeding vessels until a satisfactory hemostasis is achieved and to preserve as far as possible the renal parenchyma by adopting a completely reabsorbable embolic material as the autologous clot. After a review of the literature a case is presented where a temporary embolization was performed in a young woman with brisk postoperative bleeding in a solitary kidney. The procedure was successful and the renal function was not impaired.

Adult↗

[Sub-costal xypho-umbilico flap. A new approach to the neoplastic kidney (author's transl)].

The authors suggest a new approach to the kidney tumors: the xypho-umbilical-subcostal flap incision. This incision offers the advantages of the transversal as well as of the longitudinal approaches and gives a very satisfactory exposition of the surgical field. The authors report 52 cases of renal tumors operated on with this approach in the last 5 years: because of the optimal view it allows and of the lack of complications they suggest this incision as a method of choice in the majority of the cases of renal tumor.

Humans↗

Transcatheter embilization of the hypogastric arteries in cases of bladder hemorrhage from advanced pelvic cancers: followup in 9 cases.

Bilateral transcatheter embolization of the hypogastric arteries is effective hemostatic treatment for patients with chronic life-threatening bladder hemorrhage from advanced pelvic cancers. We reviewed 9 cases in which this procedure had been done to investigate the immediate results, clinical effects, complications and late results. The minimum followup is 1 year except for 4 patients who were followed until death, which occurred in less than 1 year. Bleeding relapse occurred in only 2 cases and another embolization procedure was done in 1 case without major complications. A considerable decrease in the size of the tumor was noted in 1 patient after the bilateral hypogastric arterial embolization procedure. A rare complication, the Brown-Séquard's-like syndrome, is discussed.

Aged↗