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Biomedical subjects

D Vanel

Publications and source records attributed to D Vanel.

At least 127 records · Page 7Linked to original sources
PubMed1987

[Value of magnetic resonance imaging of cancers of the uterine cervix and corpus. Preliminary study apropos of 9 cases of cancer of the corpus and 20 cases of cancer of the cervix].

We studied nine cases of endometrial carcinoma and twenty of cervix carcinoma. Correlation with histology is made after curietherapy in 8 cases of endometrial carcinoma. Tumor is not always seen and particularly when there is no mass effect on macroscopic examination. Myometrial invasion is not seen with accuracy: the interruption of "junctional zone" is not a good sign. The cervix tumors are well seen on T2 sequences before any treatment. There extra uterine extension is difficult to appreciate. The best results of RMI were in the follow-up after radiotherapy. Therefore it appears actually to us the best indication of RMI.

Evaluation Studies as Topic↗
PubMed1985

Problems and pitfalls in the use of computed tomography for the local evaluation of long bone osteosarcoma: report on 30 cases.

Forty-eight, computed tomography (CT) examinations undertaken in 30 patients with osteosarcoma of long bones were studied in detail, their diagnostic information being compared with that obtained from corresponding plain films. The latter were of more value in assessing peripheral bony involvement, by cortical extension and periosteal reaction, while the former, in general, permitted more accurate observation of extensions into adjacent soft tissues. Recognition of such extensions, however, was vitiated when they arose in relation to the proximal ends of the tibia, fibula, and humerus and when a haematoma had developed as a result of a biopsy. Plain films were also of more value in appreciation of response to chemotherapy. On the other hand CT is the only examination which permits a satisfactory study of intramedullary extensions of the tumour and in consequence is invaluable in determining the exact sites required for local resection. No cases of skip metastases were observed in our series, although similar appearances due to nutrient vessels or bony ridges, remote from the primary tumour, were noted on several occasions. Differentiation of these densities proved to be easy, particularly in the case of nutrient vessels when examination of the contralateral bone showed them to be symmetrical. Several authors have described the role of CT in the evaluation of local extensions. This paper reports the difficulties and errors encountered by us.

Bone Neoplasms↗
PubMed1985

[Chemotherapy of osteogenic sarcoma].

Functional results and survival have been improved in osteosarcoma during the last ten years, thanks to better conservative surgical techniques and more efficient drugs to prevent metastases. Of the several possible programmes of chemotherapy, the authors considered that the T10 programme of Rosen is the most reliable, this author claiming a survival rate of 90 p. 100 with an average follow-up of twenty months. This programme was adopted by the authors in the Paediatric Department of the Gustave Roussy Institute (Villejuif). Thirty one patients were treated and assessed after an average follow-up of 19 months. The results were favourable, only three patients presenting with metastases. One died. Amongst the thirty surviving patients, twenty-three were treated by local resection and eight by amputation.

Adolescent↗
PubMed1985

Contribution of computed tomography in six sacrococcygeal chordomas.

Six sacrococcygeal chordomas were studied with CT at the Institut Gustave-Roussy. Only one was examined at the time of the initial diagnosis and CT made a valuable contribution to this. In other cases, CT determined the possibility of initial surgical excision and the field of radiotherapy and helped make a reliable diagnosis of local recurrences. CT seems to be the best examination to use for the early diagnosis of chordomas and recurrences, which will perhaps help improve the prognosis of this serious disease.

Adult↗
PubMed1984

Chondrosarcoma in children subsequent to other malignant tumours in different locations.

During recent years the combination of surgery, radiotherapy, and multiple chemotherapy in the treatment of patients with cancer has resulted in increased survival periods and, in some cases, complete cures. In children, however, the subsequent development of other and apparently unrelated malignancies has been observed 20 times more commonly than in a control group. This paper reports the occurrence of chondrosarcoma of the femur in two children who had been treated successfully for malignant tumours of soft tissue. One of these tumours was a malignant fibrous histiocytoma in the muscles of the forearm; the other was a rhabdomyosarcoma of the cheek. The intervals between termination of treatment of these lesions and recognition of the chondrosarcoma were five years and 10 years, respectively. In addition to surgical and radiotherapeutic measures, both children had received high doses of chemotherapy.

Adolescent↗
PubMed1984

Pulmonary evaluation of patients with osteosarcoma: roles of standard radiography, tomography, CT, scintigraphy, and tomoscintigraphy.

Sixty-one radiologic evaluations were performed on 32 patients with possible pulmonary metastases from osteosarcoma. CT scanning was performed 61 times; standard chest radiography, 58; tomography, 36; scintigraphy, 40; and tomoscintigraphy, 33. Using CT as a reference (positive or negative results only), the sensitivities of the other examinations were 57% (32% of total metastases) for standard radiography, 88% (48%) for tomography, 21% (5%) for scintigraphy, and 41% (8%) for tomoscintigraphy. Of the 193 metastases, 98 were subpleural and 95 were parenchymatous. Five patients had surgery and the others had follow-up. One false-positive CT scan was thus detected. The authors' current evaluation of patients with metastases from osteosarcoma includes chest radiography and CT; the other three examinations are performed only before surgery.

Adolescent↗
PubMed1984

Contribution of computed tomography (CT) in the study of 24 head and neck embryonic rhabdomyosarcomas in children.

Our study of 24 head and neck embryonic rhabdomyosarcomas in children confirms the substantial contribution of CT: -to the diagnosis, by showing the soft tissue mass, the bone destruction especially at the skull base, orbital walls and walls of the maxillary sinuses and intra-orbital or intra-cranial extension, -for the follow-up during treatment, it shows the efficacy of treatment, confirms the diagnosis of complete remission and contributes to an evaluation for recurrence.

Child↗
PubMed1984

[Value of x-ray computed tomography in the diagnosis and surveillance of abdominopelvic recurrence of cancers of the uterine cervix. Apropos of 38 cases].

A retrospective study was conducted involving all case reports of patients treated for uterine cervix cancer, and investigated by a CT scan for suspected or follow up of a recurrence between Jan. 1981 and Nov. 1982. CT scan findings are described and the value of the method assessed; it appears to be very effective for diagnosis of recurrence in lumbar aortic lymph nodes, since it was the only examination enabling positive diagnosis in 13 out of 15 cases. Its diagnosis value is less in pelvic tumor recurrence, directly accessible to clinical examination (3 diagnoses only out of 9 cases). The CT scan is a reliable exploratory procedure since only 4 examinations were normal of the 38 completed. Possible therapeutic applications are discussed.

Adult↗
PubMed1983

Study of three radio-induced malignant fibrohistiocytomas of bone.

Malignant fibrohistiocytoma (MFH) is one of the most frequent malignant tumours of soft tissues [6]. Its classification as a bone tumour, however, is relatively recent [1]. In addition to primary MFH in bone, the entity has been observed to occur as a secondary phenomenon, some cases having complicated pre-existing infarcts of bone [4]. This paper reports three cases of MFH of bone developing as a consequence of previous radiation therapy.

Bone Neoplasms↗
PubMed1983

[Computed x-ray tomography in the study of 16 undifferentiated epitheliomas of the cavum nasopharyngeal type in children].

CT scans were performed in 16 children with undifferentiated epitheliomas of the cavum nasopharyngis type. The CT scan provided the most precise data during initial investigations, especially clear information being obtained on any intra-orbital or intracranial extension, which may occur without clinical signs. The scan is also a valid method for determining efficacy during treatment, and for the early detection of recurrences.

Adolescent↗
PubMed1983

Radiological findings in 23 pediatric cases of malignant histiocytosis (MH).

Malignant histiocytosis (MH) is a disease which clinically and histologically resembles non-Hodgkin lymphoma. Tumoural cells appear to be derived from histiomonocytes. Clinical signs commonly include: high fever, sudden onset of extreme fatigue, diffuse painful polyadenopathies and infiltrated cutaneous nodules. This study involved the radiological findings of 23 pediatric cases of MH. Thoracic involvement is very frequent (69%) and most often involves mediastinal lymph nodes. Interstitial (34%) and pleural (38%) lesions are often associated. Nine of 21 (42%) lymphographies showed pathologic changes, the most frequent pattern in retroperitoneal nodes was multilacunar and nodes were moderately enlarged. Some isolated lymph nodes were normal. Bone lesions were rare and were either lytic or sclerotic.

Adolescent↗
PubMed1983

[Preoperative radiologic localization of nonpalpable breast lesions. Technics and value. Apropos of 33 cases].

The aim of pre-operative radiologic localization is to facilitate surgery by reducing operation time and by limiting the size of excision of a benign lesion. The detection technique, the so-called "crochet" method, is described and compared with others reported in the literature. Using this method, 33 nonpalpable lesions were detected over a 6 month period and 15% of these cases had malignant tumors.

Breast Neoplasms↗