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Biomedical subjects

D Prokopowicz

Publications and source records attributed to D Prokopowicz.

At least 91 records · Page 5Linked to original sources

[Distribution of antibodies against Encephalitis ixodica viruses among north-east healthy populations of Poland].

We have undertaken the investigations for the detection of the presence of antibodies against Encephalitis ixodica viruses among North-East population of Poland. We have found these antibodies in 6.5% among 676 of tested healthy persons. The highest % of detected antibodies were noted in forest rangers and in physicians acting as hunters. Our data seems to indicate that Encephalitis ixodica is still actual disease in this region. Therefore one can suggest the necessity vaccination against Encephalitis ixodica.

Adult↗

[Complications imminent in patients with salmonellosis].

In 1038 patients with salmonellosis treated in the last 20 years in Department of Infectious Diseases, Medical School, Białystok and literature data defined, distribution and type of complications and consequences these diseases. In acute period of salmonellosis complications are: hypovolemic or infectious and toxic shock, metabolic acidosis, circulation collapse and ileus paralytic. As a late complications are mentioned organs changes and anemias. Salmonellosis nowadays may exist as a complications diseases with immunodeficiency (AIDS).

Acquired Immunodeficiency Syndrome↗

Activity of specific IgG, IgM and IgE antibodies in human trichinellosis.

The activity of IgG, IgM and IgE antibodies to somatic antigen of Trichinella spiralis in the sera of patients with trichinellosis at various intervals after infection was examined by means of ELISA. Mathematical analysis of the dose-response curves was used. Elevated level of IgG and IgM antibodies of relatively high avidity and of rather low IgE avidity was documented. Amount or avidity of IgG antibodies was found to be most useful for the diagnosis of trichinellosis (85% positive results in patients' sera). The isotype of IgM avidity constitutes a better diagnostic value than the amount of it (60% and 35% of positive results, respectively).

Adult↗

[Appendicitis and its atypical causes].

The authors analysed 2849 patients who were admitted to the Department of General Surgery, Regional Hospital in Pisz in the years 1980-1989 with symptoms suggestive of appendicitis. In 983 cases surgical intervention was abandoned, because the symptoms regressed spontaneously or were caused by diseases of other organs. The pathological conditions associated with appendicitis are analysed in 1866 surgically treated patients. Cases of appendicitis caused by Oxyuris vermicularis, Salmonella-enteritidis and actinomycosis (one case each) and appendicular carcinoma (2 cases) are described in more detail. Attention is called to the aetiology, pathogenesis and treatment of these rare causes of appendicitis.

Actinomycosis↗

[Incidence of so-called hepatic failure syndrome in relation to infection with hepatitis B virus (HBV) in epidemiological and environmental studies of the rural population in the Suwałki and Białystok regions 1978-1990].

In years 1979-1991 has been analysed the selected health epidemiological indices is related with liver pathology and viral hepatitis B infections in rural population of Białystok region. In 11,086 analysed persons of an agricultural sector the frequency of antigenemia HBs (0.25-2.5%) was higher that in control groups of urban populations (0.3-0.6%). In 12 years time period observation of chronic hepatopathy syndrome, demonstrated the increased tendency with parallel pathologic increased values of serum A1AT activity and with increased tendency of HBs antigenemia.

Adolescent↗

[Risk of development of hepatitis B virus infection among alcoholics].

The frequency of incidence of positive serological markers of hepatitis B virus infection among a population of alcoholics in the region of Białystok has been analysed. It was demonstrated that the highest frequency of detection of hepatitis B virus infection appears in a group of patients with post-alcoholic liver cirrhosis (60 percent). Acute virus hepatitis of the B type in alcoholics is characterised by a tendency towards retarded seroconversion of HBe antigen to HBe antibody with a subsequent development of chronic infection and liver cirrhosis.

Alcoholism↗

[Strongyloidiasis and its current treatment].

A case of strongyloidosis and giardiasis was observed in a women aged 62 years. The treatment included tinidazole, metronidazole and ercefuryl. Modern views on the epidemiology, clinical course and therapy of this parasitic infestation are discussed.

Antinematodal Agents↗

[Toxocariasis].

Up to present time the data concerning toxocariasis++ have been presented. Toxocariasis++ is difficult for diagnosis because of lack of specificity and multiorgan changes due to the invasion by Toxocara canis or cati. We pay attention the problem distribution of this parasitosis in Poland and world is still actual especially among children. We have presented epidemiological data and means diagnosis of this diseases and the treatment patients and prophylaxis has been stressed.

Adult↗

[Some indices of organism reactivity in chronic trichinellosis].

Sixty four patients who had passed the acute phase of trichinellosis 3, 4, 5 and 8 months and 1, 2 and 4 years earlier, have been examined with respect to their clinical condition, persistence of possible subjective complaints which could be associated with the acute phase passed, leucocytosis, absolute number of acidophilic granulocytes in blood, indices of immunological response, both humoral (IgG, IgA and IgM) and cellular (percentage of T and B lymphocytes in blood), serotonin level in blood, monoamino-oxidase activity in blood serum and passive hemagglutination reaction with trichinellosis antigen. It has been found that the frequency of occurrence and intensity of subjective complaints decreases with time. Changes in humoral and cellular reactivity, and long-lasting persistence of antibodies against the trichinellosis antigen, determined with passive hemagglutination method, have been also observed in particular patients.

Adolescent↗

[Serotonin and the immunologic reactivity of the body in taeniasis].

Blood serotonin level, 5-HIAA in 24 h urine, serum immunoglobulins-IgG, IgM, IgA, percentage of lymphocytes T and B in rosette test were ascertained in 3 groups of patients with taeniosis, treated with Radeverm (32 patients), Praziquantel (22 patients) and Yomesan (10 patients). Primary hyperserotoninemia and higher level of 5-HIAA in post-treatment values were not uniformly differentiated. The same tendency was observed in post-treatment values of immunoglobulins and lymphocytes T and B as compared with values before treatment.

Adult↗