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Biomedical subjects

D Miller

Publications and source records attributed to D Miller.

At least 631 records · Page 35Linked to original sources
PubMed1983

Tape lid retraction.

A method of retracting the upper lid with sticky tape is described. Such a tape retraction eliminates the need for a third hand in office procedures such as limbal suture removal, corneal foreign body removal, and anterior segment photography.

Adhesives↗
PubMed1983

Estimating the power of a minus spectacle while worn by the patient.

This paper presents a new method of estimating the power of a minus spectacle lens without removing the spectacle from the patient's face. The examiner shines a small light toward the spectacle and measures the separation between the images reflected from the front and rear surfaces of the lens. The study presents a relationship between separation of reflected images and the power of minus lenses from 0 to -12 D. The article also contains a theoretical explanation of the phenomenon.

Eyeglasses↗
PubMed1983

Pigmented corneal implants: a surgical treatment for iridectomy related optical complications.

Initial evaluation in rabbits demonstrates that corneal implants made from prolene and nylon sutures flattened into strips appear promising as a means of covering diplopia or glare-inducing iridectomies. Two-month follow-up studies showed the implants to be well tolerated in the corneal stroma. Results of the studies suggest that black prolene films of 50 to 70 micrometers in thickness, contoured to follow the corneal curvature, would be the ideal configuration for such implants.

Animals↗
PubMed1982

Chemotherapy of advanced salivary gland neoplasms.

Fourteen patients with advanced salivary gland malignancies were treated with combination chemotherapy. Five of 13 patients responded to cyclophosphamide and adriamycin and two patients in the responding groups underwent further potentially curable treatment, rendering them disease-free. Three patients with mucoepidermoid carcinoma failed to respond to this regimen, but two of three patients treated with a combination of cisplatinum, bleomycin and methotrexate responded. The potential role for chemotherapy in the treatment of salivary gland malignancies is discussed.

Adult↗
PubMed1982

Effect of sodium hyaluronate on corneal wound healing.

With the development of the use of sodium hyaluronate for endothelial cell protection during anterior segment surgery, we were interested in the effect of sodium hyaluronate on corneal wound healing. Therefore, the following experiment was performed. Corneal incisions were made in both eyes of 14 albino rabbits. Sodium hyaluronate was used to fill the anterior chamber of the test eye, and balanced salt solution was used in the control eye. The wounds were sutured wih 10-0 nylon. On the seventh postoperative day, and strength was measured. After suture removal, the intraocular pressure was raised until the wound burst. Results showed no statistical difference between these and control eye.

Animals↗
PubMed1982

A new glare tester for clinical testing. Results comparing normal subjects and variously corrected aphakic patients.

A simple, inexpensive, readily available, easy-to-service clinical glare tester combines an audioviewer able-top projector with a series of specially made slides. Each slide supplies a constant glare source and a variable-contrast, central target. The device was evaluated on 161 normal subjects, 144 patients with cataracts, and 110 aphakic patients whose visual acuity was corrected with spectacles or intraocular lenses. Results showed that aphakic patients, irrespective of the mode of correction, were statistically more glare sensitive than normal phakic patients. Further results confirmed earlier studies that demonstrated that glare sensitivity also increased with age in normal eyes. Broad potential exists for using this method of glare testing in industry, transportation media, and medicolegal and and clinical ophthalmologic studies.

Aged↗
PubMed1982

Clinical characteristics of patients with variant angina complicated by myocardial infarction or death within 1 month.

Of 132 consecutive patients hospitalized during a 5 year period because of active variant angina, 18 died or had a myocardial infarction within 1 month. In 4 patients an episode of pain and S-T elevation unrelieved by calcium antagonist drugs and intravenous nitroglycerin persisted for more than 1 hour, inducing cardiogenic shock and death before the appearance of Q waves and elevated serum enzyme levels. In the other 14 patients myocardial infarction developed in the electrocardiographic leads in which S-T elevation had occurred during attacks of variant angina. Clinical features were not helpful in distinguishing the 18 patients with complications from the other 114. Angina at rest had been present for less than 1 month in 7 of the 18 patients with infarction compared with 31 of 114 in the other group (probability [p] not significant [NS]). Before infarction the artery presumed to be perfusing the involved territory contained a fixed stenosis of 70 percent or more of luminal diameter in 8 of the 14 patients with complications who had coronary arteriograms compared with 50 of 112 in the other group (p = NS). In 13 of the 18 patients, complications occurred in spite of large doses of calcium antagonist drugs. In 11 of these 13, attacks of variant angina were monitored for 3 to 17 days both before and during treatment. All 11 had fewer attacks with treatment and 5 had no attacks. Daily attacks per patient decreased from 4.6 +/- 4.3 to 0.5 +/- 0.7 (mean +/- standard deviation) (p less than 0.01). It is concluded that in variant angina of recent onset myocardial infarction occurs frequently and unpredictably. Myocardial infarction may occur in the absence of severe fixed lesions and in spite of apparent clinical improvement with administration of calcium antagonist drugs.

Adult↗
PubMed1982

Toxicity of aggressive multimodality therapy including cisplatinum, bleomycin and methotrexate with radiation and/or surgery for advanced head and neck cancer.

A combined modality regimen employing induction chemotherapy with cisplatinum, bleomycin and methotrexate followed by surgery and/or radiation therapy was initiated in patients with advanced squamous cell carcinoma of the head and neck. In the first 23 patients treated with this program there was a 90% response rate to induction chemotherapy (9% CR and 81% PR). Toxicity associated with radiotherapy, but not surgery, was increased with 11 of 23 patients (48%) who experienced some toxicity during or immediately after radiotherapy. Mucositis was worse than expected and severe delayed mucositis was seen in 2 patients, one or whom required hospitalization. Late complications, possibly related to therapy included one myocardial infarction and one episode of hypoglycemia, both of which were fatal. One other patient voluntarily failed to take prescribed oral leucovorin, dying of unrescued methotrexate toxicity during adjuvant therapy, a questionable suicide. Further follow-up and analysis of failure will be necessary to determine if the value of a combined modality regimen in producing an increased cure rate and long term survival will out weight increased toxicity.

Adolescent↗
PubMed1982

Podiatric Surgery: the need for a second opinion.

A second-opinion podiatry program, designed to contain costs and enhance the quality of care, was established in the greater New York City area by the Building Service Employees' Health Fund. All nonemergency foot surgery recommended by a podiatrist that cost over $100 was included in this program. Of the 363 individuals who had a second opinion, 82 per cent were confirmed for surgery; however, the confirmation rate among those seeing a podiatrist serving as consultant was 94.3 per cent, while the confirmation rate of those seeing an orthopedists serving as consultant was 49.5 per cent. For every condition, the podiatrists overwhelmingly confirmed the need for surgery. Conversely, the orthopedists were more conservative in their recommendations regarding surgery. The program's cost was $311,813. If a second opinion consultation wasn't required for removal of corns or ingrown toenails, the total would be much less. It seems sensible (economically and medically) to encourage or require a consultation with an orthopedist for conditions such as bunions, hammertoes and heel spurs, and not to require a second opinion consultation for superficial podiatric conditions such as corns and ingrown toenails, which are treated predominantly by the podiatrist.

Adolescent↗
PubMed1982

Cholecystitis: its occurrence with cholelithiasis associated with a non-01 Vibrio cholerae.

A 28-year-old pregnant woman was brought to the hospital complaining of epigastric pain. An exploratory laparotomy revealed acute cholecystitis with cholelithiasis, and a cholecystectomy was performed. A Gran-negative rod grew from a culture of gallbladder material. The isolate exhibited biochemical reactions consistent with Vibrio cholerae, while failing to agglutinate in Vibrio 0 group 1 antisera.

Acute Disease↗
PubMed1982

Improved color vision testing.

Pseudoisochromatic color vision testing plates have traditionally provided the clinician with screening-type information regarding the color with screening-type information regarding the color vision of patients. The introduction of a variable-color filter, through which the patient views these plates during testing, produces quantifiable results while exploiting the clinical advantages of the color plates. Thus, this approach allows the quick classification and quantification of color vision defects in a clinical setting. The results of this study on 153 subjects show that a variable-color filter combined with a series of traditional pseudoisochromatic plates can be successfully used on patients in a typical ophthalmology clinic to identify normal persons, protanopes, and deuteranopes. The results of the new test correlated well with those of standard tests.

Adult↗