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Biomedical subjects

D K Goette

Publications and source records attributed to D K Goette.

At least 37 records · Page 2Linked to original sources
PubMed1985

Sweet's syndrome in subacute cutaneous lupus erythematosus.

A 67-year-old man being treated with prednisone, 15 mg/day, for subacute cutaneous lupus erythematosus developed widespread, tender, erythematous plaques, arthralgias, and fever. Clinically, the cutaneous lesions mimicked lupus erythematosus. The diagnosis of acute febrile neutrophilic dermatosis, or Sweet's syndrome, was confirmed by histologic examination of three biopsy specimens, which revealed prominent dermal edema, extensive infiltration with intact and karyorrhectic polymorphonuclear leukocytes, and perivascular and appendiceal lymphocytes in the absence of leukocytoclastic angitis.

Humans↗
PubMed1985

Pseudomelanoma in a black patient.

A worrisome lesion in a 62-year-old black man prompted a review of the differential diagnosis of pigmented lesions involving palmar skin.

Black People↗
PubMed1984

Lichenoid benign keratosis.

A histopathologic study of 108 lesions of lichenoid benign keratosis from 104 patients confirmed previously observed clinicopathologic features such as involvement of whites, age range of 35 to 65 years, female predominance, single keratosis, common location on the arm or presternal area, and failure of clinical recognition of the lesion. Histologically, lichenoid benign keratosis can be diagnosed by the characteristic lichenoid appearance, parakeratosis, an infiltrate occasionally containing plasma cells and eosinophils, and remnants of lentigo-like changes at the periphery of the lesion. The clinical information of a solitary lesion and suspicion of a premalignant or malignant diagnosis aids in establishing the pathologic diagnosis of the disease. Direct immunofluorescence studies of tissue from seven lesions of lichenoid benign keratosis resembled those seen in lichen planus. Features distinguishing lichenoid benign keratosis from lichenoid solar keratosis are discussed.

Adult↗
PubMed1984

Transepidermal elimination of actinically damaged connective tissue.

Three patients with actinically damaged skin had scaling lesions clinically resembling actinic keratoses. Histologic examination of the lesions disclosed transepidermal elimination (TE) of degenerated (solar elastotic) dermal connective tissue via a transepidermal canal, a previously undescribed phenomenon.

Aged↗
PubMed1984

Menkes's syndrome.

Menkes's syndrome (trichopoliodystrophy) is an x-linked, recessive genodermatosis characterized by hair defects, severe retardation, convulsions, progressive neurologic deterioration, and early death. Recent studies in copper metabolism suggest that Menkes's syndrome may be a storage disease in which copper is irreversibly trapped in some tissues by metallothionein, a heavy-metal-binding protein. This then gives rise to a deficiency elsewhere, particularly in the brain, causing irreversible damage in the fetus. We present a patient with Menkes's syndrome and review the clinical and metabolic aspects of this disease.

Brain Diseases, Metabolic↗
PubMed1984

Raccoon-like periorbital leukoderma from contact with swim goggles.

A 12-year-old girl developed a periorbital leukoderma from contact with swim goggles. She had worn the same goggles the preceding year and re-used them after the leukoderma had cleared without any ill effects. The hypopigmentation was believed to be caused by the leakage of breakdown products in the neoprene rubber or glue. These breakdown products may have caused a toxic rather than an allergic reaction on skin contact, inhibiting melanin production possibly by competitive inhibition of tyrosine oxidation. These chemical compounds probably leaked from the goggles and were eventually exhausted. This possibility may explain why the leukoderma did not recur after re-use of the goggles.

Child↗
PubMed1984

Treatment of palmoplantar pustulosis with intralesional triamcinolone injections.

Five patients with chronic intermittent palmoplantar pustulosis were treated with intralesional injections of 3.3 to 5.0 mg/mL of triamcinolone acetonide. Prompt clearing of symptoms and lesions ensued, lasting three to six months. Despite the discomfort experienced from the injections, patients preferred this treatment modality over others. Minor side effects included hypopigmentation, cutaneous atrophy, and, in one case, exacerbation of a latent dermatophyte infection.

Administration, Topical↗
PubMed1982

Cylindroma and eccrine spiradenoma coexistent in the same lesion.

Two patients complained of having a tender nodule. One patient had the nodule on the scalp and the other on the face. Each nodule contained a cylindroma and an adjacent eccrine spiradenoma. While eccrine spiradenoma is of eccrine derivation, the origin of cylindroma is controversial because of variable histochemical and enzyme histochemical findings. The presence of cylindroma and eccrine spiradenoma in one clinical nodule contributes circumstantial evidence for the similar derivation of both tumors.

Adenoma, Sweat Gland↗