[Classification of atrial septal defects. A new suggestion].
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Biomedical subjects
Publications and source records attributed to D Dimitrov.
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A case with symptomatic erythrocytosis in a female patient with ductus Botalli persistens is described, diagnosed and treated as erythremia vera. The heart disease advanced with no manifestations, with no complaints until the age of 30, whereon it was manifested with certain complaints and objective findings. The inadequate and difficult assessment of some of the clinical, hematological and other data as X-ray of the heart and ECG, contributed to the improper diagnosis. The patient died at the age of 54.
The results from the treatment of cardiac rhythm disorders with mexitil are reported: 26 cases with ventricular extrasystoles, 3--with ventricular paroxysmal tachycardia, 2--with supraventricular paroxysmal tachycardia, 1--with auricular extra-systoles, 7--with combined rhythm disorders in patients with ischemic heart diseases mainly. Very good treatment effect was observed in 24 patients, good--in 7, insignificant--in 3 and no effect--in 2 patients. Mexitil was concluded to be an antiarrhythmic drug with a good tolerance and well manifested therapeutic effect, mainly in ventricular rhythm disorders.
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A modification of the method of BROOKS and MUIRHEAD [2] for long-term measurement of aortic pressure in rabbits is presented. The original abdominal surgical approach is replaced by a flank extraperitoneal incision and the construction of the catheter is simplified and adapted to the new surgical procedure. The preparation and implantation of the catheter as well as the pressure recording technique are described. Using the modified catheter pulsatile and mean aortic pressure could be measured in conscious rabbits several months. Owing to the flank approach, surgical trauma and the risk of intra-abdominal infection could be minimized. On the other hand, this technique allowed simultaneous extraperitoneal procedures involving the aorta and kidney, permitting more complex haemodynamic studies.
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On the basis of clinical observations and serological investigations a mixed type of virus infection of MD-VD parainfluenza-3 and adenovirus I was established. A complex prophylaxy against the virus infections proved in 2,800 heads of cattle was carried out, also on 1,400 heads of growing animals at the age between 6 and 18 months, as well as on 2,777 calves at the age of 6 months. The results of the immunoprophylactic actions showed the leading role of MD-VD in a virus infection. Owing to the steps taken the respiratory syndrome in the calves and in the cows was suspended. The falling away of calves was reduced from 15.4% to 3.2%, and the average daily growth was increased from 220 to 470 grams.
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