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Biomedical subjects

D Dimitrov

Publications and source records attributed to D Dimitrov.

At least 109 records · Page 6Linked to original sources

Determination of phosphodiesterase activity in the presence of phosphomonoesterase using bis-p-nitrophenyl phosphate.

In the presence of phosphomonoesterase contaminations the use of bis-p-nitrophenyl phosphate to measure phosphodiesterase activity gives inconclusive values because one of the products of the phosphodiesterase or nuclease reaction becomes a substrate of the contaminating enzyme. A direct determination of the hydrolyzed phosphodiesterase substrate in the UV range is possible at the isosbestic points of the transformation of the phosphomonoesterase substrate.

Nitrophenols↗

[Ergometric assessment of lung-heart function in obesity in young men].

Increased quantitiy of lean body mass, obstructive ventilatory syndrome and elevated initial maximal arterial pressure were found in 47 obese as compared with 70 control males, all aged 18--24. With the progressive cycling loading on a veloergometer up to an oxygen uptake of 1.5 1/min--1, considerably higher oxygen uptake was established in the obese as comparable loading grades and in some of the cases--hypeptensive reaction was found. The physical work capacity (PWC170) is insignificantly decreased and the ventilatory parameters were unchanged as compared with the control group. With obesity among young males, the physical work capacity was concluded to be decreased and the frequency of cardiac activity, with submaximal loading, to be increased on both cases--per one unit of body weight, per one unit of lean body mass resp.

Adolescent↗