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Biomedical subjects

D Colin

Publications and source records attributed to D Colin.

At least 55 records · Page 3Linked to original sources
PubMed1995

A survey of pressure sore prevalence in hospitals in the greater Paris region.

In 1993 a preliminary survey was conducted in the Hospital of Gonesse to examine pressure sore prevalence. The averages obtained showed that 5.4% of patients in hospital suffer from pressure sores. This prompted a further investigation involving 12,050 patients: 5.2% were found to have pressure sores. Patients with pressure sores were significantly older (76.4 +/- 14 years) than the average age of patients in the study, and 42% of pressure sores were found in patients with neurological pathology. The majority of patients (57%) had a single pressure sore. Most were grade I lesions (38%). The greatest number of pressure sores were found on the medium and long-stay wards. A nationwide complementary survey is now being undertaken to confirm these overall results.

Aged↗
PubMed1995

Pooled reanalysis of cancer mortality among five cohorts of workers in wood-related industries.

OBJECTIVES: To provide more information regarding the risk of cancer associated with wood dust, a pooled reanalysis of data from five cohort studies was performed. METHODS: The combined cohort consisted of 28,704 persons from five studies: British furniture workers, members of the union representing furniture workers in the United States, two cohorts of plywood workers, and one of wood model makers, among whom 7665 deaths occurred. Pooled analyses were carried out for all of the cohorts combined, the two furniture worker cohorts combined, and the two plywood workers cohorts combined. RESULTS: Significant excesses of nasal [observed 11, standardized mortality ratio (SMR) 3.1, 95% confidence interval (95% CI) 1.6-5.6] and nasopharyngeal (observed 9, SMR 2.4, 95% CI 1.1-4.5) cancer were observed. That for nasal cancer appeared to be associated with exposure to wood dust but was based solely on cases from the British furniture worker cohort, while that of nasopharyngeal cancer was observed for furniture and plywood workers and was associated with both high and low probability of wood dust exposure. Some support for an excess risk of multiple myeloma was also observed but was less clearly associated with wood dust exposure. No excesses of lung, larynx, stomach, or colon cancer were found to be associated with any surrogate indicators of wood dust exposure. CONCLUSIONS: Workers exposed to wood dust may have an excess risk of nasopharyngeal cancer and multiple myeloma in addition to sinonasal cancer. The limitations of this study would tend to obscure relationships, rather than create false positive findings.

Cause of Death↗
PubMed1995

Ankle systolic blood pressure following sub-maximal and maximal exercises in healthy young men.

Although recent studies have compared the effect of progressive exercise tests to constant moderate work load tests on ankle systolic blood pressure (ASBP) and ankle to arm index (AAI) in claudicants, little is known about the relation of ASBP and AAI to work load in healthy young men. Fifteen normal volunteers were asked to cycle 40, 60, 80, 100% of VO2max. Ankle and humeral pressures were recorded simultaneously, at rest and 1 minute after the end of each test. Thereafter, AAI was calculated as the ratio of ankle to humeral systolic pressure. Compared to resting values: 134.8 +/- 13.9 mmHg, ASBP increased significantly following sub maximal tests up to 157.8 +/- 28.1 mmHg (p < 0.005), but was not increased following maximal exercise: 141.5 +/- 28.2 mmHg (NS). On the other hand, AAI showed a progressive decrease from 1.14 +/- 0.06 at rest to 1.06 +/- 0.08 (p < 0.005), but 0.98 +/- 0.07 (p < 0.005), to 0.84 +/- 0.06 (p < 0.005) and to 0.75 +/- 0.09 (p < 0.005) following 40, 60, 80 and 100% of VO2max respectively. In summary, AAI following exercise is inversely related to workload whereas ASBP is not. We suggest that when studying ankle systolic blood pressure response to heavy load exercises, results should always be compared to humeral pressure, and expressed as ankle to arms indexes.

Adult↗
PubMed1995

Methods for quantitative analysis of trabecular bone structure.

Bone mineral density accounts for 70% to 80% of the mechanical resistance of bone but is unrelated to bone tissue structure. The vertebral fracture risk increases with advancing age irrespective of whether or not bone mineral density decreases, suggesting that changes in bone microarchitecture contribute significantly to the development of osteoporosis. In contrast to bone mass, bone architecture is difficult to evaluate. Among the various methods developed to investigate bone structure, biomechanical studies are of limited value since they are done on cadaver bones. Measurement of microarchitectural parameters (e.g., mean trabecular thickness, density and separation) in bone specimens obtained by needle biopsy is the gold-standard technique. Parameters reflecting trabecular interconnections (e.g., total number of nodes and free ends) can also be measured on needle biopsy specimens. New techniques of as yet unproven validity include star volume and trabecular bone pattern factor measurement. Noninvasive techniques capable of supplying qualitative information about bone tissue are also under study. Ultrasonography can theoretically provide data on bone microarchitecture but has not yet been proven useful in clinical practice. Statistical, structural, or fractal analysis techniques can be used to evaluate bone texture on digitized roentgenograms, computed tomography sections, or magnetic resonance imaging displays; although this approach holds great promise, it is still under evaluation and has not yet been compared with histomorphometry. Lastly, the apparent relaxation time of bone marrow determined using magnetic resonance imaging may also provide information on bone structure.

Biomechanical Phenomena↗
PubMed1994

The "anatomic" view of the suprarenals in medical imaging.

Based on coordinates derived from three series of anatomic sections, the authors propose a view for tomographic investigation, applicable in MRI and ultrasound, which reconstructs the ideal image of the suprarenal gland in its quadrilateral as described by Testut. This "anatomic" view is 45 degrees vertical and oblique, intermediate between the sagittal and frontal views, which it can advantageously replace. A new aspect of suprarenal tomography, recalling the image of a triskele, is described in the context of this view.

Adrenal Glands↗
PubMed1994

[Characteristics of fractures of the distal part of the clavicle in children].

Fractures of the clavicle are frequent in children and mostly affect the middle third. On the other hand, traumatic fractures of both medial and lateral thirds of the clavicle are rare. The lesions have special characteristics: difficulty in diagnosis for the medial third; risk of callus formation in the absence of surgical reduction of the lateral third. The authors report two observations of fractures of the medial and lateral thirds of the clavicle; they insist on the value of investigation by CT scan.

Child↗
PubMed1991

Growth, carcass characteristics, and lipid composition of adipose tissue and muscle of pigs fed canola.

Sixty-one finishing pigs (53.4 kg) were fed a control diet (containing soybean meal) or diets containing 20% intact canola (IC) or 20% ground canola (GC) for 8 wk. Diets were not isocaloric. Daily gain and feed efficiency were not affected by dietary treatment, but pigs fed GC ate less than pigs fed either IC or the control diet. Carcass measurements, obtained on 43 of the pigs, were not affected by diet. For 27 pigs, fatty acid composition of perirenal adipose tissue (PRF), subcutaneous adipose tissue (SCF), and longissimus muscle (LDM) was analyzed. Nine pigs (three per treatment) were randomly selected for fatty acid composition analysis of intramuscular adipose tissue (IMF) and for cholesterol analysis of several tissues. Pigs fed canola had greater (P less than .05) proportions of mono- and polyunsaturated fatty acids and less (P less than .05) saturated fatty acids in PRF and SCF. The differences were more pronounced for PRF than for SCF. In the LDM, pigs fed canola tended to have elevated levels of unsaturated fatty acids at the expense of the saturated fatty acids, but this effect was significant for linolenic acid only. The fatty acid composition of IMF was not affected by diet (P greater than .05). Diet did not alter the cholesterol content of the tissues, but cholesterol in IMF was higher (P less than .05) than in PRF, SCF, and LDM. In conclusion, 20% IC or GC did not alter growth performance or carcass characteristics of pigs. Feeding of canola increased the degree of unsaturation of PRF and SCF, but it had less effect on IMF and LDM.

Adipose Tissue↗
PubMed1991

[Techniques of autologous transfusion in hip surgery: a retrospective study].

A retrospective study was carried out on 99 patients undergoing hip surgery to evaluate the efficacy of three autotransfusion techniques on sparing of homologous blood. Preoperative normovolemic hemodilution (HDN), delayed autotransfusion (ATD) and recuperation of blood lost during surgery (RSPO) were studied. Patients were divided into 5 groups: group HDN, group ATD, group ATD + HDN, group RSPO, and the control group. The hematocrit was followed intra and postoperatively within these five groups, and mean values homologous blood transfusions calculated for each group. Comparison of mean values was performed using variance analysis (p less than 0.02). The association of delayed autotransfusion and preoperative hemodilution was most effective in sparing homologous blood (0.11 +/- 0.3 unit, p less than 0.02): however these results were obtained with a substantial drop in hematocrit which fell well below the 30% minimal accepted value at the end of the operation. There was no significant difference between delayed autotransfusion (0.35 +/- 0.8 unit) and preoperative hemodilution (0.7 +/- .01 unit) in sparing homologous blood. Hematocrit values with delayed autotransfusion were greater than these obtained with preoperative hemodilution. The difference was significant at the beginning of the operation (p less than 0.001), but not significant at the end. Recuperation of blood lost during surgery was least effective in sparing homologous blood (1 +/- 1.2 unit, p less than 0.02). Because of the moderate decrease in hematocrit, there are very few contraindications to delayed autotransfusion. Recuperation of blood lost during surgery should be associated with another autotransfusion technique.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1991

[3-dimensional reconstruction of x-ray computed tomographic views in fractures of the acetabulum].

In 21 cases of acetabulum fractures of 19 patients, the authors compare the findings given by three dimensional reconstructions of axial CT scan cuts with the plain films. The number of CT scan cuts is reasonable for each patient. Working time is about 20 to 30 minutes for the technician. In the cases of complex and displaced fractures, three dimensional imaging brings often decisive informations for the therapeutic management of these patients. Unusual views are often allowed but completely adapted to each type of fracture.

Acetabulum↗