Analysis of preoperative and postoperative lung scintigraphy in patients undergoing elective hip surgery.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to D Bergqvist.
Explore the source record for details and available documents.
A long-time follow-up of 43 patients with minor or intermediate degree blunt renal injuries is presented. A low incidence of complications, including hypertonia, calculi, and infections, was noted, but in three patients, the function of the injured kidney was affected, and two of these also had structural abnormalities as demonstrated by urography. It is recommended that the follow-up of patients with blunt renal injuries should include both urography and renography.
The development of penetrating abdominal injuries during 30 years has been compared between a rural and an urban area. There was an increase in number of injured patients but the causes of injury did not change. In the urban area stab wounds, assaults, and injury combined with alcohol intoxication were significantly more frequent than in the rural, where gunshot wounds dominated. Indications for laparotomy and therapeutic management did not differ. There were minor but statistically insignificant differences in complications and mortality. Although the material is small exteriorization must be recommended as the method of choice in penetrating civilian colon injuries as it is in war injuries.
Explore the source record for details and available documents.
Hemostatic plug formation has been studied in the rabbit mesenteric microcirculation during normovolemic hemodilution. A hemodilution method has been developed which maintains a constant platelet count. Using this method the primary hemostatic plug formation time (PHT) and the total hemostatic plug formation time (THT) has been assessed for different degrees of hemodilutions. Both PHT and THT are significantly prolonged for arterioles perfused with low hematocrits (10.6 and 14.2). At a hematocrit of 19.0 the hemostasis is most effective with the shortest hemostatic plug formation times.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The pathophysiological significance of the biphasic venous emptying curves from the lower limbs in venous occlusion plethysmography was examined in three patients peroperatively by clamping the iliac veins in different locations. The clinical significance of biphasic curves was analysed in fifty-four patients, thirty-one of whom were pregnant and twenty-three had a suspected deep vein thrombosis. It was found that the primary venous emptying time (PVET) was helfpul in locating the obstruction. Patients with femoral and pelvic vein thrombosis had shorter PVET than patients with pregnancy or other pelvic vein obstructions. With PVET of 0.5 sec, or shorter, thrombosis should be strongly suspected. The ratio between the slow and fast emptying phases was useless in localization of the intrapelvic process.
To analyse changes in background factors, injury pattern, and prognosis regarding blunt abdominal trauma in Sweden, the 30-year postwar (1946--75) development was investigated in a rural district. 396 patients were treated, showing a great increase during the last 5 years. The highest frequency was seen in patients aged 11--30 years. Abdominal trauma occurred most commonly during July and August. The growing aetiological importance of road accidents is shown. Equestrian accidents were common early in the period and again towards the end. The incidence of cerebrally confused patients increased. The organs most commonly traumatized were kidney, liver, and spleen. The frequency of multiple intra-abdominal injuries and also associated extra-abdominal injuries increased with time. There was a tendency towards shorter hospital stays. Mortality rates did not change during the period, even though injuries have become increasingly severe (judged by the Injury Severity Score). It is concluded that the improved care of patients compensated precisely for the increased severity of injuries, as reflected in mortality.
In 169 consecutive women undergoing cesarean section, of which 90 were performed as an emergency and 79 electively, the frequency of deep vein thrombosis was evaluated with a non-invasive diagnostic technique - strain gauge plethysmography. Three patients developed thrombosis (1.8 per cent), all after acute surgery. No specific background factors were associated with the development of thrombosis. In 26 of the 79 patients (33 per cent), who were plethysmographed before operation, a biphasic venous emptying indicated venous outflow obstruction by the pregnant uterus.
The literature on low-dose heparin thrombosis prophylaxis has been reviewed to evaluate differences in effect and bleeding complications between heparin administered at twelve- and eight-hour intervals. The more frequent administration gives a slightly greater reduction of the overall frequency of thrombosis but is not more effective in reducing extensive thrombi or fatal pulmonary emboli. Moreover, it causes more haemorrage, which is why it is concluded that the twelve-hourly interval must be recommended.
A prospective randomized controlled study has been undertaken to evaluate two different prophylactic treatments against postoperative thromboembolic complications after hip surgery. Patients with hip fracture (77) and patients undergoing elective hip arthroplasty (213) were separately randomized into one of three groups: control, dextran 70, or low-dose heparin. Deep vein thrombosis was diagnosed in both groups with the 125I-fibrinogen test and pulmonary perfusion defects in the arthroplasty group with a combination of pulmonary X-ray and perfusion scintigraphy. The frequency of thrombosis was significantly higher in untreated hip fracture patients than in untreated arthroplasty patients. In hip fracture patients both treatments significantly reduced the frequency of thrombosis. Only dextran reduced the frequency of major thrombosis and in the heparin group one fatal pulmonary embolism occurred. After elective hip surgery the overall frequency of thrombosis was not influenced by the two treatments, but with dextran 70 thigh thrombi were reduced and with low-dose heparin the frequency of bilateral thrombosis was reduced. Two patients in the control group died of pulmonary embolism, but the frequency of pulmonary perfusion defects was not influenced by the treatment. Bleeding and transfusions were the same in the three groups.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
On screening of a normal material 1 man was found (age 37) who on repeated determinations had a low alpha 2M, namely 25 % with electroimmuno assay according to Laurell. Investigation of the family revealed that the mother (age 69) and one daughter (age 5) had low values too. All other coagulation and fibrinolytic components were normal. They had no signs of increased fibrinolysis and normal levels of alpha 2-antiplasmin, alpha 1-antitrypsin and antithrombin III. Liver function tests were normal. It seems to be an inherited deficiency. The transmission is apparently autosomal dominant and the affected members heterozygotes. The defect has not caused any clinical symptoms. This family appears to be the first reported with an alpha 2M deficiency.
Explore the source record for details and available documents.
The value of thermography as a screening method for postoperative deep vein thrombosis has been evaluated in 308 patients (616 legs). Comparison was made with the 125I-fibrinogen test. The overall diagnostic agreement was 81.0 per cent; the sensitivity was 62.1 per cent and the specificity 90.3 per cent. The agreement increased with proximal extension of the thrombi. Thermography became positive 0.26 days after the 125I-fibrinogen test but in 19.8 per cent thermography was positive before a positive fibrinogen test.
In order to estimate the rate of local complications of phlebography we studied a one-year series of 477 patients. Half of the patients were examined with a comparatively highly concentrated contrast medium and half with a more diluted one. Eight patients had local complications, verified by biopsy and/or thermography and plethysmography. One had a deep vein thrombosis, five had a superficial thrombosis and two had a skin necrosis. There were more complications after the use of the more concentrated medium, six against two. The frequency of clinically significant complications to phlebography is rather low, but high enough to warrant attention to the risks of the method. The concentration of the contrast medium should be as low as possible, and the time that the vessels are exposed to the chemical trauma as short as possible. A hypothesis is brought forward that skin necrosis with slow healing could be secondary to arterial thrombosis caused by extravasal contrast injection.