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Biomedical subjects

D Bergqvist

Publications and source records attributed to D Bergqvist.

At least 577 records · Page 32Linked to original sources
PubMed1982

Lung complications after elective hip surgery.

A total of 350 patients undergoing elective hip surgery were retrospectively studied as regards pulmonary complications. The study is based on the findings of pre- and postoperative chest X-rays and of pulmonary perfusion scintigrams. Twenty-seven per cent of the patients had pulmonary complications of some kind. Twelve per cent had a change in the postoperative as compared to the preoperative X-ray, though most of the changes were minute. In 15.4 per cent there were scintigraphic signs of pulmonary embolism and of these 30 per cent of the patients had symptoms of pulmonary infectious disease. Two patients died from pulmonary embolism. The study shows a low frequency of serious pulmonary complications after elective hip surgery.

Aged↗
PubMed1982

Effect of volume expanders on the lysability of ex vivo thrombi in the rabbit.

The lysability of ex vivo thrombi before and after the infusion of dextran 70 (0.5 g/kg, 1.5 g/kg and 2 g/kg), dextran 40 (1.5 g/kg), albumin 5% (1.5 g/kg) and normal saline (0.3 g/kg) was studied in rabbits. All rabbits received 125I fibrinogen before the experiment. The thrombi were treated with plasmin or sodium chloride and the radioactivity released in the supernatant by the thrombus was determined. The thrombus weight was also recorded. A gradual increase in the lysability of thrombi after dextran 70 administration was observed and the maximum effect occurred 24 hours later. Increasing dose of dextran 70 did not potentiate the release of 125I fibrin degradation products in the supernatant, but did significantly decrease the thrombus weight during the first hours postinfusion, Dextran 40 was found to have a similar action but the effect was shorter and the lysability at 24 hours was similar to the preinfusion values. Albumin 5% and normal saline increase the radioactivity released from the thrombi to the supernatant but no change in the thrombus weight was observed. A similar result was obtained in the control group. The present investigation demonstrated that increasing doses of dextran 70 potentiate the effect on thrombolysis demonstrated by statistically significant decrease in the thrombus weight. Furthermore, albumin 5% and normal saline increase the release of 125I fibrin split products in the supernatant but did not have any effect on the thrombus weight and finally, the rabbit showed a marked spontaneous fibrinolysis probably related to the stress, anesthetic agent and surgical manipulation.

Albumins↗
PubMed1982

Venous emptying from the calf. Methodologic report and effect of intermittent pneumatic compression.

In 17 patients undergoing surgery for varicose veins of the leg, the elimination rate of 99Tcm-macroaggregated albumin from the calf of the contralateral leg was studied. The leg had no discernible varicosities. This substance has not previously been used in such a context. Its theoretical advantages are discussed. A mathematical method for interpreting the elimination rate is presented. Two modes of intermittent calf compression--a slow and a fast pattern--were compared, and also control group without compression. The elimination rate of the radioisotope was slower with compression than without. Possible interpretations and implications of this observation are discussed.

Female↗
PubMed1982

Abdominal trauma in persons older than 60 years.

Abdominal trauma occurring in persons older than 60 years over a 30-year period (1950-79) in a well defined region of Sweden was reviewed. The 177 patients comprised 12.5% of the total with abdominal trauma during that period. Road traffic accidents were the main cause of trauma (48% of cases). The incidence of motor-car accidents rose sharply during the first two decades of the study. Injuries to the liver and bile ducts and multiple intra-abdominal injuries were more common in the elderly than in younger patients, but injury to the abdominal wall was less common. A tendency towards more severe injuries and multiple trauma with extra-abdominal involvement emerged during the study period. The mortality rate was 27.6% in the patients older than 60, but 9.1% in the overall patient series with abdominal trauma. One-third of all the deaths among the older patients were directly due to the abdominal trauma. One consequence of the increasing numbers of old people in the general population is probably that more and more cases of abdominal trauma will be seen in the higher age groups.

Abdominal Injuries↗
PubMed1981

A comparative study of Dextran 70 and a sulphated polysaccharide in the prevention of postoperative thromboembolic complications.

A prospective randomized study has been performed, comparing a semisynthetic polysulphated xylan of vegetable origin (mol. wt approximately 4000) with Dextran 70 as prophylactic agent against postoperative thromboembolic complications following elective abdominal surgery. A total of 109 patients entered the trial and the analysis after exclusions is based on 86 patients. The overall frequency of 125I-labelled fibrinogen test-detected thrombosis was 2.9 per cent in the polysaccharide group against 19.2 per cent in the Dextran 70 group (P less than 0.05). There was no difference in haemorrhage or different complications.

Abdomen↗
PubMed1981

Abdominal trauma during thirty years: analysis of a large case series.

Studies have been made in 1407 patients of the causes, the organs involved and the outcome of injury to the abdomen in patients needing admission to hospital in an area of Southern Sweden, between 1950 and the end of 1979. The proportion of female patients and those aged over 60 increased significantly. The seasonal distribution of the injuries showed significant change, with a drop in the initially high frequency sustained during the summer months. Penetrating injuries were rare, but increased in the 1970s. Road traffic accidents as the cause of abdominal injuries rose to a maximum of 56 per cent in the late 1960s. The numbers of injured organs and the frequency of other associated injuries rose gradually until the mid-1970s, after which there was a slight decrease. The spleen, liver and large blood vessels were the organs which were increasingly often injured. The annual incidence of various visceral injuries per 100 000 population was calculated. The number of patients with a delay of at least 24 hours before operation fell significantly and there was a tendency to shorter hospital stay. The mortality curve showed a peak in the late 1960s.

Abdominal Injuries↗
PubMed1981

Complications of phlebography: a randomised comparison between an ionic and a non-ionic contrast medium.

A high frequency of thrombotic complications of phlebography with conventional ionic contrast media has recently been reported by several writers. A switch to expensive non-ionic media has been recommended. Such a switch would undoubtedly place great restrictions on the use of this valuable procedure. In this prospective study two types of contrast media were compared. Only patients undergoing phlebography prior to operation for varicose veins and with no history of thrombotic disease were included. Post-phlebographic observations were made by microscopy of surgically removed vein specimens and by plethysmography. No significant difference emerged between the two groups of patients as regards thrombotic complications. A disadvantage of ionic media is their higher rate of immediate side-effects, such as pain. These effects, however, are clinically less important than the thrombotic complications, and they can be reduced by good phlebographic technique. In the authors' opinion, phlebography with ionic media remains justifiable, provided that the examination time is short and the dose and concentration of contrast medium are low.

Clinical Trials as Topic↗
PubMed1981

Aortic occlusion following blunt trauma of the abdomen.

Blunt injuries to the abdominal aorta with initial survival are rare. Two cases of blunt aortic occlusion are reported: one with acute abdominal symptoms and leg ischemia and one with delayed intermittent claudication. The first patient died 9 days postinjury with possible sepsis and bronchopneumonia. The second presented with delayed symptoms 9 years postinjury: fibrous thickening of the intima, a dense, fibrous band around the aorta and left renal vein. After a Dacron graft from the descending thoracic aorta to the external iliac arteries the patient recovered and is employed full time.

Adult↗