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Biomedical subjects

C Selli

Publications and source records attributed to C Selli.

At least 109 records · Page 6Linked to original sources

Stratification of risk factors in renal cell carcinoma.

One hundred fifteen patients underwent surgical treatment of renal cell carcinoma. Survival time was analyzed by statistical regression methods in order to determine the joint significance of stage, using both the Robson and TNM classifications, histologic grade, cell type, and demographic features of the patient sample. Grade and cell type were essentially interchangeable with respect to predicting survival in patients with and without metastatic disease. The strong association between these two factors explains and supports this result. The presence of metastases dramatically altered survival. Local extent of the tumor was an important indicator of survival in the nonmetastatic group of patients, but was not a statistically significant factor in those patients presenting with widespread disease. Venous involvement was not found to be of prognostic significance in either group. Age and weight loss contributed to predicting survival in the nonmetastatic patient group in addition to the measures of disease extent already discussed. Sex and race were not significant indicators of length of survival. In the group of patients with metastatic disease, no difference in survival was observed between soft tissue and bony metastases.

Adenocarcinoma↗

A, B, O (H) antigenic determinants in superficial transitional cell tumors of bladder.

The initial tumors of 21 patients who earlier had presented with superficial noninvasive transitional cell carcinoma of the bladder and who subsequently underwent cystectomy for invasive disease were examined by the specific red cell adherence test. Eighteen of 21 initial tumors (85.7%) were antigen negative. The time from initial tumor resection ranged from twelve to 168 months (mean thirty-eight months). Loss of blood group antigens indicated enhanced biologic aggressiveness of tumors. However the interval to invasion is sufficiently variable as to preclude the use of this assay for timing of radical cystectomy.

ABO Blood-Group System↗

Management of patients with concurrent primary tumors of bladder and prostate.

The clinical course of 33 male patients presenting with concurrent primary tumors of the bladder and prostate was reviewed. Twenty-four of 33 patients were treated by radical cystoprostatectomy. The remaining 9 patients were treated by more conservative means. Seventy-four per cent of the patients survived five years. A rationale for management of concurrent primary tumors of the bladder and prostate is presented.

Adult↗

The effect of cigarette smoke on aryl-hydrocarbon hydroxylase (AHH) activity of the human kidney.

AHH activity was measured in kidney cortex biopsies obtained during surgery from patients with hydronephrosis and from unaffected portions of kidneys with renal cell carcinomas. AHH activity was slightly, but not significantly, higher in the group of non-smoking cancer patients when compared to non-smoking hydronephrotic subjects. Smoking induced a significant increase of AHH activity in the hydronephrotic kidneys but not in cancer kidneys, probably due to the higher baseline values and scatter in the cancer group. Pooling cancer and non-cancer kidneys, smokers had a higher AHH activity than non-smokers, this increase being dose-related.

Adenocarcinoma↗

Surgical treatment of male urinary incontinence.

Between January 1975 and December 1981 we treated 34 men with urinary incontinence with surgical intercavernous embedding of the bulboperineal urethra along its entire length. The etiology of incontinence was sphincteric damage following either prostatectomy (30 cases) or pelvic trauma (4 cases). All patients had complete neurologic integrity of the detrusor, 25 (75 per cent) had complete urinary continence, 5 (15 per cent) experienced considerable improvement, while 4 were failures. Followup ranged from 7 years to 4 months. Details of the surgical procedure are described, preoperative and postoperative management is emphasized and results are presented.

Adult↗

Myxoid liposarcoma of the bladder.

We report a case of myxoid liposarcoma of the bladder dome. Treatment consisted of partial cystectomy and pelvic lymphadenectomy. The patient had no evidence of recurrence 30 months postoperatively. This is the first reported case of primary bladder localization of liposarcoma.

Adult↗

Bladder herniation after transpubic urethroplasty.

We report 2 cases of bladder hernia following repair of complex posterior urethral strictures by transpubic bulboprostatic anastomosis and omentoplasty. One patient was treated successfully by repair of the defect with a synthetic mesh. The presence of concomitant pubic diastasis is thought to be a contributing factor, as well as the use of omentum to fill the dead space.

Hernia↗

Prostatomembranous urethral injuries: a review of the literature and a rational approach to their management.

Controversy surrounds the management of prostatomembranous urethral injuries. We herein present 38 patients and review the findings of 538 in 19 reported series. Results indicate a high risk of stricture, impotence and incontinence if conventional early urethral realignment techniques are used. Therefore, it is suggested that this approach be reserved for cases demanding immediate intervention (high riding bladder, associated rectal tear, concomitant bladder neck injury or continued bleeding), and that all others be managed by initial suprapubic cystostomy alone and delayed urethroplasty. Urethroplasty selection is discussed.

Erectile Dysfunction↗

Retrovesical echinococcal cyst causing acute urinary retention.

A case report of a fifty-six-year-old man with acute urinary retention due to a retrovesical echinococcal cyst is presented. He had a history of surgery for hepatic hydatidosis; diagnosis was made preoperatively with the help of conventional x-ray studies, pelvic sonography, and CT scanning. Treatment consisted of removal of the cyst.

Echinococcosis↗

Prolactin and prostate: a chronobiologic study.

A possible role of prolactin in prostatic disease has been claimed, but the results are so far misleading. Among the several factors that influence serum prolactin levels, temporal variations, notably circadian, are prominent. This paper shows an impairment in serum prolactin, chronobiologically investigated, in 12 patients with benign prostatic hypertrophy and in 7 patients with prostatic carcinoma. However, a single serum sample cannot be sufficient and may sometimes be misleading if not plotted with an adequate temporal reference standard (chronodesm).

Aged↗

Surgical repair of ureteral defects.

A nineteen year surgical experience with 35 patients requiring repair of ureteral defects is reported. Causes of ureteral damage are described, and the result of 18 patients treated with ileal ureter are compared with those of 17 cases where surgical procedures preserving urothelial continuity were used, such as bladder psoas hitch and renal autotransplantation. Significantly better results were observed with the latter techniques.

Adult↗

Adrenal myelolipoma.

The case of a 46-year-old man with a 6 cm right adrenal myelolipoma is described. This benign tumor presents a "fatty" density at c.t. scan, and can be easily recognized at intraoperative biopsies.

Adrenal Gland Neoplasms↗

Management of traumatic posterior urethral stricture by one stage perineal repair.

Ten male patients with posterior urethral strictures secondary to trauma of the pelvis were treated with a one stage perineal repair, consisting of excision of the strictured segment and direct anastomosis between the bulbous urethra and the apex of the prostate. Repair was performed after an interval from trauma ranging from three months to 22 years. The mean followup time was 22 months. Excellent results were observed in eight patients, diffuse distal urethral narrowing in one patient and recurrent stenosis requiring further repair in another patient. Continence and potency were unaffected. This technique is applicable to the majority of posttraumatic posterior urethral strictures, less than 2 centimeters in length, and does not preclude further repair.

Adult↗

Leiomyosarcoma of the kidney: report of two cases with common angiographic findings.

Two cases of renal leiomyosarcoma are described. At angiography both cases presented common findings consisting of: (1) central hypovascularity surrounded by peripheral tumor neovascularity and (2) oval-shaped areas that rapidly filled with contrast medium. This angiographic appearance, although not previously described in such tumors, cannot be claimed to offer a key to preoperative diagnosis because it may be found in the more common hypernephromas with central necrosis.

Adult↗

Late intrascrotal metastases from renal cell carcinoma.

A case of bilateral epididymal metastases appearing sixteen years after nephrectomy for renal cell carcinoma is reported. A literature review of intrascrotal metastases from renal cancer reveals that they are uncommon. The possible mechanisms of spread are discussed.

Adenocarcinoma↗

Experience with ureterocalyceal anastomosis.

Experience with 10 cases of ureterocalyceal anastomosis is reported. Most cases involved scleroatrophic scarring of the pelvis after repeated stone surgery, and 1 case each for failed pyeloplasty, tuberculous stricture of the pelvis, transitional cell carcinoma of the pelvis and calyces, and ureteropelvic junction obstruction associated with renal malformation. Three patients had a solitary kidney. End-to-end ureterocalyceal anastomosis was performed in 5 patients; laterolateral in 1 case, and ureteropyelocalyceal anastomosis in the remaining 4. In 3 cases omentoplasty was also performed.

Adult↗