Biomedical subjects
Publications and source records attributed to C Ratnakar.
Among the fungal pathogens the species Fusariam solani causing systemic infection is very rare and generally causes systemic infection only in an immuno-compromised host. We report a systemic infection caused by F. solani in a non-immunocompromised adult male, to our knowledge the first such case report.
Blastomycosis-like pyoderma, a rare skin lesion which may clinically resemble true blastomycosis, is seen in immuno-compromised individuals. We report one such case in chronic myeloid leukaemia.
One hundred and thirty-nine cases of rhinosporidiosis diagnosed histopathologically over a period of 4 years were analysed. Nasal rhinosporidiosis is common among males who bathe in stagnant ponds while ocular rhinosporidiosis is common among urban females. There is a seasonal variation in the incidence of nasal and ocular rhinosporidiosis.
Proton magnetic resonance (PMR) relaxation times were measured for dissected malignant and normal tissue derived from breast cancer patients. Relaxation time measurements (T1, T2) were carried out at a RF frequency of 20 MHz and at a temperature of 27 degrees C with a Brucker PC 120 NMR Process analyser. The tissue types were confirmed by histopathological examination. In general T1 values were found to be longer for malignant tissues as compared to normal tissues which is in agreement with the earlier observations. The measured T2 values do not exhibit the malignant tissues above. The percentage of water content was also measured in both normal and malignant tissue and was found to be considerably larger in tumour tissue as compared to normal tissue. These results are discussed on the basis of two fraction fast exchange models of water molecules and confirm that PMR relaxation time measurement plays an important role in the differentiation of cancerous tissues from that of normal.
Explore the source record for details and available documents.
A rare case of malignant fibrous histiocytoma involving the whole eye is reported in an Oriental 60-year-old man. Six months' follow-up after exenteration did not show any evidence of local recurrence or distant metastases.
A 24-year-old East Indian woman presented with an inflammatory swelling in the supranasal quadrant of the left orbit and vertical diplopia. The motility disorder was of typical acquired Brown's syndrome. Histopathological examination of the lesion revealed Cysticercus cellulosae, a parasitic cyst known to produce a severe inflammatory reaction. To our knowledge this is the first report of acquired inflammatory Brown's syndrome caused by cysticercosis.
A rare case of diverticulum of the lacrimal sac associated with rhinosporidiosis is reported. The clinical presentation and possible pathogenesis are discussed.
The development of carcinoma in a thyroglossal cyst is rare. This report describes the presence of papillary carcinoma in a giant thyroglossal cyst and reviews the literature regarding the clinico-pathological features of the disease and its management.
A hitherto undescribed case of an osseous choristoma of the thyroid presenting as a single cold nodule is presented. The possible origin of the lesion is discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A total of 38 cases of human cysticercosis were diagnosed by histopathological examination within a period of 10 years in JIPMER Hospital which serves the population of Pondicherry and adjoining regions of South India. Analysis of our cases showed that there was no sex predilection and 34 of the 38 cases were within the first three decades of life. A curious yet striking feature was that in 37 of the 38 cases the lesions were localized above the level of the umbilicus. Lesions of the subcutaneous tissue formed the largest group with 18 cases. Seventeen of the 38 cases were confined to the eyes, forming the largest series to be reported from India. In six cases there was evidence of brain involvement with postmortem confirmation in three. The JIPMER Hospital records showed a high incidence of epilepsy in this region with a ratio of one out of every four patients attending the neurology clinic. As cerebral cysticercosis is a known cause of epileptiform convulsions, it is suggested that many cases of epilepsy may in fact be due to cerebral cysticercosis. The majority of our patients were drawn from the rural population. We analysed the social customs and related factors which are peculiar to this region and were indirectly responsible for the high incidence of cysticercosis.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.