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Biomedical subjects

C Gianturco

Publications and source records attributed to C Gianturco.

At least 55 records · Page 3Linked to original sources
PubMed1976

Therapeutic vascular occlusion utilizing steel coil technique: clinical applications.

The stainless steel coil has been utilized for permanent intravascular occlusion of the proximal portion of the renal, hepatic, splenic, and internal iliac vessels. This therapeutic approach has been successful in the management of renal arteriovenous fistulas, renal carcinomas, neoplasms of the liver, giant cell tumors of the sacrum, and in hypersplenism. The techniques involved and clinical uses are discussed.

Adult↗
PubMed1975

The use of prostaglandin E1 to enhance the angiographic visualization of the splanchnic circulation.

Superior mesenteric angiograms were obtained in a series of dogs before and again after the injection of a 1-ml bolus of prostaglandin E1 (0.1-1.0 mug/kg) through the angiographic catheter. The prostaglandin E1 produced, on the average, a 100% increase in the superior mesenteric arterial blood flow with only minimal changes in the heart rate, systemic arterial pressure, and portal venous pressure. Opacification of the portal venous system was consistently enhanced after the prostaglandin E1. The arterial phase was preserved by increasing the rate of contrast administration.

Animals↗
PubMed1975

A feasibility study for percutaneous retroperitoneal lymph node biopsy.

A percutaneous technique for the biopsy of retroperitoneal lymph nodes was studied in animals and cadavers. Access to the retroperitoneal space from the groin to the diaphragm has been achieved, and satisfactory biopsies of iliac and lumbar lymph nodes opacified by pedal lymphangiography have been obtained. Further investigations, however, are needed to improve the technique and to minimize the potential hazards associated with this procedure.

Animals↗
PubMedDate not supplied

Hepatic artery infusion and chemoembolization in the management of liver metastases.

Hepatic metastases rather than the primary neoplasm usually dictate the course of the disease and patient's survival. For unresectable disease, intraarterial infusion of chemotherapy, embolization, and chemoembolization are viable alternatives. Intraarterial therapy for hepatic metastases is based on the dual blood supply of the normal liver (portal vein, 75%, and hepatic artery, 25%) and that of the tumors (hepatic artery, 90%). Intraarterial infusion delivers a higher concentration of chemotherapy, whereas chemoembolization adds ischemia and increased contact time with the tumor. Selective vascular occlusion for infusion, redistribution of the blood supply and pulsatile flow enhance the delivery of therapeutic agents to the liver.

Antineoplastic Agents↗