Medulloblastoma--a histomorphological profile.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to B Prakash.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The authors emphasize the meticulous search for microangioma under magnification in cases of spontaneous haematoma. Two cases of low flow (cryptic) arteriovenous malformations are described. The CT scan and angiography are non-contributory in detecting such lesions. These small-sized angiomas are buried in the wall of the haematoma cavity. Histologically there is evidence of thrombosis in arteriovenous malformation.
Explore the source record for details and available documents.
Four cases of NPA with extra-nasopharyngeal extensions have been presented, two of which had an intracranial extension. On of the cases with intracranial extension underwent a transtemporal craniotomy removal and four temporal fossa. The other three cases were managed by the sublabial and transantral routes. Methods of pre-operative diagnosis of such extensions have been discussed and the importance of pre-operative recognition of extension in every NPA has been emphasized. Various approaches to the lateral and intracranial extensions have been reviewed. We feel that, for lateral extensions, sublabial and/or transantral or transzygomatic approaches are adequate, while the radical approach of Karnik is to be preferred only in large lateral extensions and in cases of intracranial extensions without symptoms of a space-occupying intracranial lesion. However, for patients with intracranial symptoms, a staged procedure is indicated and is safe for the patient.
Explore the source record for details and available documents.
A case of intramedullary schwannoma of the brain stem is reported, and its possible origin discussed. The importance of a biopsy in brain-stem tumors is emphasized.
Explore the source record for details and available documents.
In cases of closed head injury temporal lobe lesions e.g. contusion, laceration, pulping, or intracerebral haematoma frequently result in an expanding process. These are frequently associated with an overlying subdural haematoma. Eighty five cases of such lesions from a consecutive series of 1,000 cases of head injury have been analyzed. The lesions are caused by severe injury resulting in loss of consciousness and skull fracture. Most of them are contre-coup lesions. Clinically they manifest themselves like any other acute or subacute intracranial hematoma. The majority of the patients have contralateral hemiparesis and pupillary abnormalities. Carotid angiography is valuable for diagnosis. These lesions are likely to be missed when exploratory burr holes are made or, are erroneously diagnosed as acute subdural haematoma or brain oedema. Smaller lesions, not showing progressive deterioration, may respond to conservative treatment. However, surgical decompression is essential in most cases A frontotemporal osteoplastic craniotomy or a large Scoville trephine hole is essential to deal with these lesions adequately.
A patient with a rare case of Klippel-Trenaunay-Weber syndrome presented with paraplegia due to compression by a vertebral and epidural cavernous hemangioma. The metameric distribution of the large cutaneous vascular nevus provided the clinical clue to the nature of the spinal lesion. The association of the two lesions is explained in the basis of developmental anomaly.
Seventy cases of pituitary adenoma were analysed for evidence of haemorrhage. It was present in 18 cases. These are classified into four groups, acute, acute on chronic, chronic, and late sequelae of pituitary apoplexy, and an example of a patient in each group is given. The diagnosis and management are discussed.
Explore the source record for details and available documents.
The clinical features and management of 18 patients with congenital heart disease and a brain abscess are reviewed. Except for one patient all had cyanosis. All abscesses were large, containing at least 50-60 ml of pus, and mostly unilocular. Bilocular and multilocular abscesses were also encountered. The organisms cultured from the pus had little relation to the mortality. Tapping may be the final investigation, and is also the treatment of choice. The high mortality (50%) is attributed to the delay in referral of these patients to a neurosurgical unit.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Four cases of aneurysmal bone cysts of the spine are described. Problems of nomenclature, pathogenesis, and treatment are discussed with reference to the literature. Complete excision is the treatment of choice whenever possible. However, subtotal excision and adequate spinal decompression followed by radiotherapy provide satisfactory results.
Explore the source record for details and available documents.