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Biomedical subjects

B Mazur

Publications and source records attributed to B Mazur.

At least 37 records · Page 2Linked to original sources
PubMed1997

[Evaluation of the occurrence of bronchial asthma in children from clinical material in the years 1983-1994].

The aim of the study was to assess the prevalence of bronchial asthma in children aged 0-15 year old hospitalized in the years 1983-1994. The analysis of the material was carried out on the basis of 13,514 disease histories of children admitted to hospital in the eleven years' period. The essential criterion that decided about further clinical and statistical analysis was recognition of bronchial asthma as a primary disease. In the studied clinical material bronchial asthma was diagnosed in 333 patients i.e. 2.5%.

Adolescent↗
PubMed1995

Peak expiratory flow values in children relative to the degree of atmospheric air pollution.

The purpose of the study was to determine peak expiratory flow (PEF) values in children from three regions with different degrees of atmospheric pollution. The study included 1415 healthy children aged 7-9 years. In each child five measurements of PEF (1/min) were performed with a Vitalograph. The highest result was considered. The greatest degree of airway resistance, as reflected in low PEF values, was noted among children living in the Upper Silesian Industrial Region and in the Olkusz region where the degree of atmospheric pollution is high compared with Zarki.

Air Pollutants↗
PubMed1994

[Lead poisoning in children from the industrial region of Silesia--markers of chronic intoxication].

In the paper the degree of lead micro-intoxication was assessed in school children from the region of emissions of the Mining-Ironworks Complex "Bolesław" in Bukowno. The study included 323 children of either sex aged from 7 to 14 years. In these children the levels of selected lead intoxication markers were determined--concentration of zinc protoporphyrin (ZnPP) in the erythrocytes and concentration of delta-amino-laevulinic acid (ALA) in urine. The obtained results were compared with corresponding results in the control group which consisted of 163 children of the same age, living in a control area without exposure to heavy metals. In the studied group in all age subgroups, significantly higher ALA concentrations in urine were observed in comparison to the control group. At the same time, exceeding of upper acceptable range of ALA concentration in the organism was five times more frequent in this group. On the other hand, the concentration of ZnPP in the erythrocytes failed to show any significant differences between the compared groups in any of the analysed age subgroups. On the basis of the obtained results it was demonstrated that the school children living in the region of emissions of the MIC "Bolesław" had biochemical features of long-term lead microintoxication. As it seems, the concentration of ALA in urine is of greater diagnostic value in comparison to the concentration of ZnPP in the erythrocytes in screening examinations in these children.

Adolescent↗
PubMed1994

[Lead poisoning in children from the industrial region of Silesia--hematologic indices].

In the paper, the basic parameters of blood morphologic pattern were assessed in school children exposed to toxic heavy metal emission. The studies included 323 children aged from 7 to 14 years, living in the region of emissions of the Mining-Ironworks Complex "Bolesław" in Bukowno. In these children haemoglobin concentration, haematocrit and erythrocyte and leucocyte counts were determined using routine laboratory tests. The obtained results were compared with corresponding results in the control group which consisted of 163 children of either sex living in a control region without exposure to heavy metals. In the studied group in most age subgroups significant decreases of erythrocyte count haemoglobin concentration and increases of haematocrit value were observed in comparison to the control group. At the same time, in these children, ten times higher, in relation to the control group, incidence was found of haemoglobin concentrations below 120 g/l, characteristic of anaemia. As it seems, one of important factors causing the decrease of the value of the parameters of blood morphologic pattern in the studied children is chronic microintoxication with lead, manifesting itself as significantly increased concentration of delta-amino-laevulinic acid in urine which is a sensitive marker of this intoxication.

Adolescent↗
PubMed1994

[Comparison of values for peak expiratory flow (PEF) measured with various devices in children].

Peak expiratory flow (PEF) (1/min) is a simple and reliable index of airway narrowing. The purpose of the work was the comparison of the PEF values obtained using two various measuring devices (Vitalograph Pulmonary Monitor and Clement-Clarke mini Wright) in preschool children. The total number of 290 healthy and normally developed children aged from 4 to 6 years (142 girls and 148 boys) were studied. Each child carried out at least 5 PEF measurements with the above mentioned devices. The highest PEF values obtained using each of the devices were taken into account in further analysis. Statistically significantly higher PEF values were demonstrated in five- and six-year-old girls and in four- and five-year-old boys, measured using the mini-Wright device as compared with the Pulmonary Monitor.

Child↗
PubMed1994

[Peak expiratory flow and certain spirometric indices in boys with bronchial asthma in the clinically silent period].

An analysis between relationship of PEF (measured with Vitalograph meter) and dynamic volumes (FVC, FEV1 and PEFII), maximal expiratory flow volumes (MEF25%, MEF50%, MEF75%) measured with Pneumoscreen by Jaeger was carried out in 9 year old boys (26 with atypic asthma and 36 healthy volunteers). Statistical significant differences were seen between PEFI (p < 0.001), FVC (p < 0.05), FEV1 (p < 0.01), and MEF25% (p < 0.02) in healthy volunteers in comparison with boys with atopic asthma in the clinically silent period.

Asthma↗
PubMed1993

[Effect of treatment at a health resort in a plains climate on peak expiratory flow values in preschool children with respiratory disorders].

PEF is the most widely used parameter to assess airflow limitations of the airways. The aim of the study was to assess the value of climatic treatment in the sub-mountainous region on PEF values in pre school age children with various respiratory diseases, inhabitants of the upper silesian industrial region. In 113 children (age 4-6) PEF values were recorded at the beginning and end of the 21 day stay at the sanatorium. PEF was recorded using the Vitalo-graph meter. The results of the study revealed an increase of PEF values was statistically significant.

Airway Resistance↗
PubMed1992

[Basic indicators of physical development of schoolchildren living in the area of an industrial plant processing non-ferrous metals].

The purpose of the study was an analysis of the basic indices of somatic development of school children in the Olkusz area with mines of zinc, lead and cadmium, and metallurgic plants processing the ores of these metals. The studied group comprised 747 children aged 5 to 14 years attending randomly selected schools in Olkusz, Bukowna and Bolesław. The height and body mass were measured on medical scales with height scale. The obtained results were compared with those of similar measurements of children in other parts of the country with different degrees of environmental pollution with non-iron metals. In the Olkusz area the height of the children was slightly smaller than in other parts.

Adolescent↗
PubMed1991

[Peak expiratory flow (PEF) in relation to body height in healthy children, measured in centile and standard diagrams].

The aim of the study was to define the centile and standard diagrams of the relation of PEF to height in healthy children. 1047 children were selected randomly from schools of the Upper Silesian Industrial District. In all PEF was recorded 5 times using a Vitalograph Peak Flow Meter. The highest levels were always taken in account. Following statistical analysis the centile and standard diagrams were calculated. These diagrams were used practically in assessing the ventilatory status of healthy and sick children.

Adolescent↗
PubMed1991

[Comparison of the degree of peak expiratory flow (PEF) in children measured with a "Vitalograph" meter and automatic spirometer SA-02].

PEF values in 475 healthy children (age 9-15 years, 138 females, 337 males) measured with a Vitalograph meter and an automatic spirometer SA-02 were compared. The results were comparable in all except in 9, 10, 11 year old boys, in whom the PEF values measured with a Vitalograph meter were statistically higher in comparison with the readings given by the automatic spirometer. The authors have demonstrated the high reliability of the Vitalograph meter in assessing PEF.

Adolescent↗
PubMed1990

[Prevalence of ascariasis and giardiasis in children from 0 to 3 years old hospitalized in the years 1980-1984 and in 1987].

The studies were carried out for six years (1980 - 1984 and in 1987) considering the frequency of invasion by A. lumbricoides and G. intestinalis in various years depending on age and sex. The clinical material involved 5948 children of either sex aged from 0 to 3 years. Ascariasis was found in 123 children (2.06%) and giardiasis in 54 cases (0.9%). The infestation was more frequent in boys and it was associated always with other diseases.

Ascariasis↗
PubMed1989

[Hypochromic anemia associated with ascariasis and giardiasis in children].

The purpose of the study was determination of the frequency of the association of hypochromic anaemia with infections by Ascaris lumbricoides and Giardia intestinalis. Among 5603 studied patients of either sex, aged 3 to 18 years ascaridiasis alone was diagnosed in 226 children (4%), and giardiasis alone in 106 cases (1.9%). The frequency of this anaemia in these groups ranged from 6% to 16%.

Adolescent↗
PubMed1988

The molecular basis of sulfonylurea herbicide resistance in tobacco.

The enzyme acetolactate synthase (ALS) is the target enzyme for the sulfonylurea and imidazolinone herbicides. We describe the isolation and characterization of the ALS genes from two herbicide-resistant mutants, C3 and S4-Hra, of Nicotiana tabacum. There are two distinct ALS genes in tobacco which are 0.7% divergent at the amino acid sequence level. The C3 mutant has a single Pro-Gln replacement at amino acid 196 in one ALS gene. This gene is termed the class I gene and is equivalent to the SuRA locus. The S4-Hra mutant has two amino acid changes in the other ALS gene. This gene is termed the class II gene or the SuRB locus. The S4-Hra mutant includes a Pro-Ala substitution at amino acid 196 and a Trp-Leu substitution at amino acid 573. Gene reintroduction experiments have confirmed that these amino acid substitutions are responsible for the herbicide resistance phenotypes. Transgenic plants carrying these genes are highly resistant to sulfonylurea herbicide applications.

Journal Article↗