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Biomedical subjects

B Lubin

Publications and source records attributed to B Lubin.

At least 37 records · Page 2Linked to original sources
PubMed1997

The alternate forms of the Positive and Negative Mood Scales: reliability, validity, and equivalence in referred samples.

The reliability (internal consistency and alternate form) of the trait version of the Positive and Negative Mood Scales in referred samples was found to be high, and the concurrent and discriminate validity was found to be moderate. As expected, means of the Positive Mood Scales were significantly higher in nonreferred samples and means of the Negative Mood Scales were significantly higher in referred samples. The alternate forms for each scale were equivalent. The Positive and Negative Mood Scales seem to be ready for use in research.

Adolescent↗
PubMed1997

Umbilical cord blood stem cells: application for the treatment of patients with hemoglobinopathies.

Even though there is recognized morbidity and death associated with bone marrow transplantation, this procedure has been performed successfully in a substantial number of patients with hemoglobinopathies. However, finding a suitable related donor is often difficult and the morbidity associated with the use of unrelated donors is high. Several reports indicate that fewer than 30% of patients with thalassemia major and fewer than 20% of patients with sickle cell anemia have histocompatible siblings. Human umbilical cord blood (UCB) contains hematopoietic stem cells capable of reconstituting bone marrow. To date, approximately 200 transplantations have been performed with UCBs. Early results suggest that, even with substantial human leukocyte antigen (HLA) incompatibility, a decrease in the incidence of graft-versus-host disease occurs with cord blood. The extent to which HLA incompatibility can be tolerated when cord blood is used has not been determined. These results raise the possibility that UCB obtained from unrelated donors could be used for transplantation in patients with hemoglobinopathies. This review summarizes current data on UCB stem cells used for transplantation in hematologic diseases. The review contains a discussion of the potential uses of UCB for patients with hemoglobinopathies and the value of programs designed to collect UCB from newborn infants with hemoglobinopathies, from siblings of patients with hemoglobinopathies, and from groups of ethnic minorities similar to those in which hemoglobinopathies are found.

Blood Banks↗
PubMed1997

Impact of a body-mind treatment component on alcoholic inpatients.

1. A group of alcoholic patients who were treated with a physical fitness program as an adjunct to the usual program showed significantly less craving for alcohol than members in the standard treatment group. 2. The group treated with physical fitness as well as therapy saw themselves as having more internal locus of control and being less controlled by powerful others. 3. Nurses are the hospital professionals most likely to be involved with important roles in exercise programs with alcoholic patients.

Adult↗
PubMed1996

Further study of the diagnostic and screening efficiency of the ST-Depression Adjective Check Lists.

In order to provide additional data on the diagnostic efficiency of the DACL in a situation in which dual diagnoses that involve depression also are considered, two groups of psychiatric patients completed DACL list E and independently were assigned psychiatric diagnoses via the Psychiatric Diagnostic Interview. Findings indicate that the DACL may be of considerable use in screening for depression. Sensitivity was high for both males and females (.84 and .80, respectively) with a cutting score of 12/13. Correct classification rates were also between 4 and 10% higher than base rates.

Adult↗
PubMed1996

Mood as a predictor of discharge from Air Force basic training.

In order to determine the predictive validity of the Total Mood score, the Negative Mood Scale, and the Positive Mood Scale of the ST-Depression Adjective Check Lists (ST-DACL), the state version of lists C and D of the ST-DACL was administered on the second day of the Air Force basic training program to 229 newly enlisted Air Force recruits (men = 113; women = 116). Findings were that DACL total score yielded the best overall classification rate, the Positive Mood Scale was most related to predicting eventual discharge, and the Negative Mood Scale was best at predicting graduation.

Adolescent↗
PubMed1996

Newborn screening for sickle cell disease: 4 years of experience from California's newborn screening program.

PURPOSE: In this article we describe the success of a unique newborn screening program for sickle cell disease and other hemoglobinopathies. We will present and discuss 4 years of experience from the California Newborn Hemoglobinopathy Screening Program. METHODS: Several aspects that ensure the success of the program will be reviewed. These aspects include (a) the use of high-pressure liquid chromatography as the initial screening technique, (b) a confirmatory testing laboratory that incorporates DNA technology and innovative protein analysis using electrospray mass spectrometry, and (c) a complex follow-up strategy that employs regional nurses to track positive results and ensure timely enrollment of infants into treatment systems. RESULTS: Of these 2 million infants screened, 492 were diagnosed with some form of sickle cell disease; 290 (58.9%) were diagnosed with hemoglobin SS, 143 (29.0%) were diagnosed with hemoglobin SC, and 47 (9.5%) were diagnosed with S beta+thalassemia. CONCLUSION: The prevalence and ethnicity data presented here demonstrate the ineffectiveness of targeted screening and justify universal screening. Had targeted screening been performed in California during the past 4 years, 58 nonblack infants with sickle cell disease would have gone undiagnosed, and 6,921 nonblack infants with sickle cell trait would not have been identified.

Anemia, Sickle Cell↗
PubMed1995

Psychometric characteristics of the trait version of the Depression Adjective Check Lists (DACL) in adult psychiatric outpatients.

Psychometric characteristics of the trait version of Set 2 (E, F, G) of the Depression Adjective Check Lists (DACL) were studied in a sample of 177 consecutive admissions to a university medical center clinic of adult psychiatric outpatients (60 males, 117 females). The SCL-90-R and the Psychiatric Diagnostic Interview also were administered. The trait DACL was shown to have high internal consistency (.90 to .92) and alternate form reliability (.86 to .92) and good concurrent (.76) and discriminant validity. The DACL (E, F, G) was able to differentiate between those with or without the presence of a Major Depression. There was a significant correlation between DACL E and levels of distress and psychopathology. In addition, the magnitude of DACL score significantly differentiated psychiatric diagnostic groups.

Adult↗
PubMed1995

Comparison of depression in the community-dwelling and assisted-living elderly.

Depressive affect in assisted living (n = 351) and community dwelling (n = 102) elderly was compared by means of the state and trait forms of Set 1 of the Depression Adjective Check Lists (DACL). Four separate analyses of covariance (age as covariate) showed the main effects of living arrangement and form to be significant on each of the four lists. Assisted living and the state form were significantly higher. Sex was not significant on any of the lists, and none of the two-way and three-way interactions reached significance. Implications of the findings for program planning for the elderly in assisted living arrangements are discussed.

Activities of Daily Living↗
PubMed1995

Factor structure of the state and trait versions of the depression adjective check lists.

The factor structure of the state and trait versions of the Depression Adjective Check Lists (DACL) was assessed. Results support the existence of two underlying factors, "negative mood" and "positive mood", which are robust across sex and age groups (elderly, young adults, and adolescents) and across referred as well as nonreferred populations.

Adjustment Disorders↗
PubMed1995

Biomarkers and pediatric environmental health.

It is now possible to identify biochemical and/or cellular changes in humans due to exposure to an environmental toxin. These changes are called biomarkers and are currently used in research studies to identify individuals exposed to specific toxic substances. Advances in the field of biomarker technology may have important implications for the detection, prevention, and treatment of certain diseases in children. This technology may enable physicians to screen children who have no clinically detectable illness for evidence of exposure to specific toxins. Such information could lead to implementation of preventive measures and development of new therapeutic strategies. However, several important issues, including potential adverse consequences resulting from the widespread use of this technology, must be considered prior to its utilization within a clinical setting. Leaders of the pediatric and public health communities should recognize the paucity of scientific data in the pediatric environmental health area, and new approaches to this important aspect of child health should be developed. This article will address several of the issues involved in pediatric environmental health and consider questions that should be answered as the potential for technology transfer becomes a reality.

Adult↗
PubMed1995

A grade-six reading level key for the multiple affect adjective check list-revised.

A scoring key containing adjectives from the Multiple Affect Adjective Check List-Revised (MAACL-R) at or below the Grade 6 reading level (MAACL-R6) was used to rescore data from two nonreferred samples (college students, ns = 52 and 78) and one referred sample of 202 from a community mental health center outpatient clinic. Reliability (measures of internal consistency and test-retest) and validity (correlations with five 5-point self-rating mood scales) were almost as high as those for the MAACL-R, and convergence among the MAACL-R6 scales was not increased. Means for the referred group were significantly higher.

Adolescent↗
PubMed1994

Norms, reliability, and concurrent validity measures of the Portuguese version of the Depression Adjective Check Lists.

This study reports normative data of depressive mood in Brazil, using a Portuguese version of the Depression Adjective Check Lists (DACL; Lubin, 1981, in press). Participants (N = 1,063) were college students drawn from randomly selected courses in 10 Brazilian universities. Cross-cultural comparisons showed that this Brazilian sample had significantly higher depressive scores compared to Hispanic (p < .01), American (p < .01), and Israeli (p < .05) samples. The results also indicated that Brazilian females (p < .05) and young adults (p < .05) reported significantly more depressive mood than males and older adults, respectively. All reliability (internal consistency, split-half, and alternate form) and concurrent validity measures were found to be appropriate and compared well to other cross-cultural samples.

Adolescent↗
PubMed1994

Development of a Critical Item Scale for the Depression Adjective Check Lists.

A critical item scale for the Depression Adjective Check Lists was developed on two psychiatric patient samples and a college student sample. Items that differentiated the nondepressed from the severely depressed subgroup of a community mental health center were cross-validated in the other two samples. A four-adjective Critical Item Scale thereby was constructed for each list of Set 2 (E, F, G) of the Depression Adjective Check Lists.

Adult↗
PubMed1994

Universal screening for hemoglobinopathies using high-performance liquid chromatography: clinical results of 2.2 million screens.

In screening for hemoglobinopathies, high-performance liquid chromatography (HPLC) achieves excellent sensitivity and specificity, while adding the very important quantitative element to the analysis. Due to the development of a rapid, automated HPLC system, California began screening 600,000 births per year in 1990 using this method. Based on confirmatory testing for 97% of the initial positive results resulting from 2.2 million screens, HPLC has proven to be clinically accurate. In conjunction with the availability of quantitative data, HPLC provides a complete screening system, eliminating the need for a second screening test, and accurately discriminating beta thalassemia compound conditions. The large degree of ethnic diversity and high birth rate in California have produced detailed and reliable birth prevalence rates for most conditions and ethnicities.

Blood↗
PubMed1994

Reliability and Validity of Set 1 of the Depression Adjective Check Lists With the Elderly

The reliability (internal consistency, alternate form, and test-retest) and validity (concurrent and discriminant) of the state and trait versions of Set 1 (lists A, B, C, D) of the Depression Adjective Check Lists (DACL) were studied in an elderly sample (N = 338). Reliability and validity estimates for both versions were sufficiently high so as to recommend their use in research with the elderly. Suggestions for further study are mentioned.

Journal Article↗
PubMed1994

Measuring the short-term mood of adolescents: reliability and validity of the state form of the Depression Adjective Check Lists.

Adequate reliability (internal consistency, and alternate form), and validity (concurrent, convergent, and discriminant) of the state version of Set 1 (lists A, B, C, D) and Set 2 (lists E, F, G) of the Depression Adjective Check Lists with two adolescent samples: F = 35, M = 29; F = 294, M = 244) were demonstrated. The lists also were shown to be sufficiently sensitive for use in measuring short-term mood. Significant grade effect was found on two of the lists of Set 1 and a significant sex effect was found on each of the lists of Set 2.

Adolescent↗