Search PubMed⌕ Search

Biomedical subjects

A Singh

Publications and source records attributed to A Singh.

At least 793 records · Page 44Linked to original sources
PubMed1980

Nuclear imaging supplementary to urography in obstructive uropathy.

In 50 patients with obstructive uropathy, nuclear imaging supplementary to excretory urography did not improve the detection of obstruction or the determination of the site or etiology of the lesion. However, rapid sequential radionuclide images showed decreased renal perfusion in 64%, more frequently than did an obstructive nephrogram (40%); this finding appeared to occur with more severe degrees of obstruction. Functional impairment of the obstructed kidney was demonstrated more often with 131I Hippuran (o-iodohippurate sodium) (91%) than with 99mTc glucoheptonate (68%) or excretory urography (66%). Neither nuclear nor urographic studies could predict the degree of functional recovery of the kidney until the increased intrapelvic pressures was relieved.

Adolescent↗
PubMed1980

Recurrent cyanotic attacks due to unilateral upper airway obstruction in infants.

Two infants presented with recurrent brief cyanotic attacks and had unilateral nasal discharge. Both were poor feeders. The triad--transient cyanotic attacks, poor feeding and unilateral nasal discharge--points to unilateral upper airway obstruction. When the obstruction was relieved, the symptoms disappeared.

Airway Obstruction↗
PubMed1980

Estimation of progesterone in buffalo milk and its application to pregnancy diagnosis.

Milk samples were collected on Days 20, 24, 28 and 40 after insemination. The percentage of fat and thr progesterone concentration in the milk were correlated (P < 0.01). Progesterone concentration in the milk of pregnant buffaloes (24.83 +/- 3.85 ng/ml) was significantly higher than that in non-pregnant animals (2.89 +/- ng/ml) on Day 20 and the difference between the two increased with time after insemination. The detection of non-pregnant animals was 100% successful at all times but the diagnosis was correct for 66, 68, 81 and 83% of animals tested on Days 20, 24, 28 and 40 respectively and predicted as pregnant.

Animals↗
PubMed1980

Renal allograft rejection: sonography and scintigraphy.

A total of 30 renal allograft patients who had sonographic B scanning and radionuclide studies of the transplant was studied as to whether: (1) the allograft rejection was associated with any consistent and reliable sonographic features and (2) the sonograms complemented the radionuclide studies. Focal areas of decreased parenchymal echogenicity were the most striking and consistent sonographic finding in allograft rejection. This was observed in most of the patients exhibiting moderate or severe rejection, but was frequently absent with mild rejection. Areas of decreased parenchymal echogenicity were not seen during episodes of acute tubular necrosis. Therefore, sonography showing zones of decreased parenchymal echogenicity was complementary to radionuclide studies in the diagnosis of allograft rejection versus acute tubular necrosis. Corticomedullary demarcation was difficult to interpret because of technical variables, and was inconsistently related to rejection in this series.

Adolescent↗
PubMed1980

Immunological relationship between strains of Theileria annulata Dschunkowsky and Luhs 1904.

The immunological relationship between the Ludhiana and Hissar strains, and between the Uruli-Kanchan, Bangalore and Jaipur strains of Theileria annulata was studied. Calves were immunised against the Ludhiana strain by the infection-treatment method, against the Uruli-Kanchan strain by the infection-treatment method or by untreated low-grade infection and against the Jaipur strain by untreated low-grade infection. After 45 days, groups of immune calves and susceptible controls were challenged with 10-tick equivalent stabilates. The ensuing host responses, body temperature, swelling of the regional lymph node, appearance of schizonts in the regional lymph node and piroplasms in blood and mortality, were studied. All five strains proved very virulent and produced severe disease in susceptible calves. Immunisation with the Ludhiana, Uruli-Kanchan and Jaipur strains conferred absolute protection against severe homologous challenges. Immunisation with the Ludhiana and Uruli-Kanchan strains conferred substantial protection against heterologous challenges with the Hissar strain, and the Bangalore and Jaipur strains, respectively. Immunisation with the Uruli-Kanchan strain gave less protection against heterologous challenge with the Jaipur strain and vice versa as some of the challenged calves showed slight swelling of the regional lymph node, two had fever, all exhibited a low-grade parasitaemia and four developed anaemia.

Animals↗
PubMed1980

Burkitt's lymphoma.

Explore the source record for details and available documents.

Burkitt Lymphoma↗
PubMed1980

Accessory flaplike tissue causing ventricular outflow obstruction.

In three cases, two in children and one in a young adult, ventricular outflow obstruction was caused by a valvelike flap of accessory endocardial tissue. The angiocardiographic feature was that of a narrow radiolucent, crescent-shaped or linear filling defect corresponding to the site of obstruction. Resection of the accessory tissue was performed in each case at the time of correction of associated conditions. In one case (a woman 20 years of age) the obstructing membrane was in the outflow tract of the right ventricle, and a ventricular septal defect was associated. In each of the other two cases the outflow tract of the left ventricle was the site of obstruction. In one (a 14-month-old boy), an ostium primum type of atrial septal defect and cleft mitral valve were associated; in the remaining case (a 7-year-old boy) complete transposition and ventricular septal defect were also present. In the latter case a Mustard procedure was performed and was followed by death. Successful results were obtained in the first two patients.

Adult↗
PubMed1979

Mutation of the non-Mendelian suppressor, Psi, in yeast by hypertonic media.

The Psi(+) extrachromosomal determinant in the yeast Saccharomyces cerevisiae suppresses certain UAA markers and increases the efficiency of suppression of UAA suppressors and certain frameshift suppressors. Although the exact nature of Psi(+) determinant is unknown, it is believed to be a self-replicating cytoplasmic factor affecting some component of the translational machinery. In this report we describe growth conditions for efficient mutation or elimination of the Psi(+) determinant. Incubation of Psi(+) cultures in hypertonic nutrient medium resulted in rapid conversion to a culture containing predominantly Psi(-) cells during the growth cycle. The kinetics of Psi(+) to Psi(-) conversion established that the occurrence of Psi(-) cells was due to induction and not to selection of pre-existing Psi(-) cells. The results suggest that the replication of the Psi(+) determinant is sensitive to hypertonic conditions.

Journal Article↗
PubMed1979

Erroneous thyroid-stimulating hormone radioimmunoassay results due to interfering antibovine thyroid-stimulating hormone antibodies.

Apparent elevation of serum thyroid-stimulating hormone (TSH) levels was found in a case of a patient receiving adequate replacement therapy after thyroidectomy for a follicular carcinoma. This was an artifact due to interference with the radioimmunoassay by circulating antibovine TSH antibodies. The double-antibody technic showed spuriously elevated levels, and the single-antibody technic showed low levels of serum TSH by radioimmunoassay in the presence of antibodies.

Animals↗
PubMed1979

A mutator affecting the region of the iso-1-cytochrome c gene in yeast.

The mutator gene DEL1 in the yeast Saccharomyces cerevisiae causes a high rate of formation of multisite mutations that encompass the following three adjacent genes: CYC1, which determines the structure of iso-1-cytochrome c; RAD7, which controls UV sensitivity; and OSM1, which controls osomotic sensitivity. The simplest hypothesis is that these multisite mutations are deletions, although it has not been excluded that they may involve other types of gross chromosomal aberrations. In contrast, normal strains do not produce such multisite mutations even after mutagenic treatments. The multisite mutations arise at a rate of approximately 10(-5) to 10(-6) per cell per division in DEL1 strains, which is much higher than rates observed for mutation of genes in normal strains. For example, normal strains produce all types of cyc1 mutants at a low rate of approximately 10(-8) to 10(-9). No evidence for multisite mutations was obtained upon analysis of numerous spontaneous ade1, ade2, met2 and met15 mutants isolated in a DEL1 strain. DEL1 appears to be both cis- and trans-dominant. The location of the DEL1 gene and the lack of effect on other genes suggest that the mutator acts only on a region adjacent to itself.

Chromosome Aberrations↗