Contact dermatitis to a copper-containing intra-uterine device.
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Biomedical subjects
Publications and source records attributed to A Rebora.
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Two middle-aged men with a cyclic eruption of transient urticarial papules of the face are described. Deposits of mucinous material were observed in cycstic spaces in their hair follicles. In direct immunofluorescence cells bearing IgE and C1q were found scattered in the dermis and were identified as mast-cells. Both patients experienced some relief of their disease in summer.
A patient on Captopril treatment is reported. This patient developed a dermatitis that clinically recalled a gyrate subacute lupus erythematosus and showed lichenoid features on light microscopy.
A patient with Richner-Hanhart syndrome had thigh skin grafted onto her heel in an attempt to improve her walking. The graft seemed to be spared by the hyperkeratosis that arrested at the periphery of the graft and formed a keratotic wall. A low-tyrosine, low-phenylalanine diet was effective in clearing hyperkeratosis.
A case of localized pemphigoid simulating dyshidrosis is described. Only direct immunofluorescence permitted a correct diagnosis.
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Recently some evidence has accumulated indicating that lichen ruber planus, especially in its erosive variety, may be an important indicant of chronic cirrhogenic hepatitis, either a chronic active hepatitis or a primary biliary cirrhosis. Usually the cutaneous lesions precede the obvious clinical features of liver disease by months or years and the erosive quality of the lesions usually indicates the presence of hepatic cirrhosis. A case is reported herein which had so typical features of both lichen planus and erosivus and chronic active hepatitis to be regarded as representative of this association. In Italy, possibly due to the high prevalence of hepatitis B virus infection, the lichen planus patients seem to have a higher probability to develop a chronic active hepatitis, whereas those in Great Britain and USA, for genetic reasons perhaps, seem to associate with primary biliary cirrhosis. The distinction of the two hepatic diseases is difficult in the earliest stage, but it is very important, because their treatments are quite different. The association lichen planus-chronic active hepatitis appears not to be fortuitous and its possible pathogenetic mechanism is proposed.
A man displayed the acute inflammatory cutaneous manifestations and the late "incontinentia pigmenti-like" lesions of Conradi-Huenermann subgroup B of chondrodysplasia punctata. The case appears as unique in the literature in that, to our knowledge, both kinds of skin changes have been described only in newborns or early in infancy.
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A patient is described in whom a neuromyopathy developed during a long chloroquine treatment for systemic lupus erythematosus (SLE). The presence of a granular deposition within the muscle fibers was observed and led to discontinuation of the drug and to a gradual recovery of muscle strength. The difficult differential diagnosis with polymyositis, steroid-induced myopathy and SLE myositis is discussed.
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