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Biomedical subjects

A Pau

Publications and source records attributed to A Pau.

At least 91 records · Page 5Linked to original sources
PubMed1982

Effect of omental transposition on to the brain on the cortical content of norepinephrine, dopamine, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in experimental cerebral ischaemia.

Local cerebral ischaemia causes a significant decrease in norepinephrine, dopamine, 5-hydroxytryptamine in the cortical brain tissue of rabbits, associated with an increase in 5-hydroxyindoleacetic acid. Previous transposition of the omentum on to the brain surface maintains, to a large extent, physiological levels of these metabolites. This study stresses the role of the transposed omentum in reducing the effects of experimental occlusion of a major cerebral artery.

Animals↗
PubMed1981

Angiomas of the cerebellopontine angle.

Angiomas situated within the pontocerebellar cistern lie superficially on the ventrolateral aspect of the brain stem. Occasionally, minor extensions penetrate into the adjacent nervous structures. Five patients bearing such lesions were operated upon, using a microsurgical technique. Radical excision was performed in all cases. Within 2 to 12 months the patients had returned to their previous occupations, being fully able to work or attend school. There is increasing evidence for the effectiveness of surgical treatment of angiomas of the ventrolateral aspect of the brain stem and the cerebellopontine angle. The illness usually presents with hemorrhages of varying severity, ranging from mild to devastating. Impairment of consciousness, contralateral hemiparesis and ipsilateral cranial nerve palsies are the most frequent neurological signs after bleeding. The outcome following excision is primarily related to the preoperative condition. No additional deficits or only minor further impairment can be expected from surgical interference. Exploration is advisable whenever the malformation appears to lie on the surface rather than within the brain stem.

Adult↗
PubMed1981

Redundant nerve roots of the cauda equina.

Four cases of redundant nerve roots of the cauda equina are reported, and the pertinent literature is reviewed. This disorder mainly affects males. The clinical history ranges from months to decades. The illness often starts with low back pain or sciatica, or both. Motor and sensory impairment of the legs dominate the further course of the disease. Serpentine filling defects in the column of contrast are a characteristic (but inconstant) feature on myelograms. Abatement of signs and symptoms occurs following adequate decompression of the redundant roots.

Adult↗
PubMed1980

Effect of omental transposition to the brain on protein synthesis in experimental cerebral ischaemia.

Occlusion of the middle cerebral artery severely affects the uptake of labelled leucine into various subcellular fractions from rabbit brain. Previous transposition of pedicled omentum to the cerebral surface maintains to a large extent the protein synthetic activity of the brain following arterial occlusion. The role of the transposed omentum in providing an effective collateral circulation and minimizing the occurrence of irreversible ischaemic lesions is stressed.

Animals↗
PubMed1980

Cerebral water and electrolytes in experimental ischaemia following omental transposition to the brain.

Occlusion of the middle cerebral artery induces a local decrease in percentage of tissue dry weight in rabbit brain, associated with flux of sodium and potassium in reciprocal directions. Cortical swelling occurs also in remote non-ischaemic areas. Previous transposition of the omentum majus to the brain minimizes the onset of oedema consequent on occlusion of a major cerebral artery. Increasing experimental evidence points to the role of omental transposition in providing an effective source of collateral circulation, thus strongly affecting the threshold for infarction.

Animals↗
PubMed1980

Long-term results of surgery for hydatid disease of the spine.

Long-term results of the surgical treatment of 18 patients with hydatid disease of the spine are reported. Recurrent signs of cord compression, requiring reoperation, occurred in half of the cases. The infestation can be controlled occasionally for over decades after the first operation, allowing the patients to have an acceptable life with their disease.

Adolescent↗
PubMed1980

Surgical removal of striate arteriovenous malformations.

Some arteriovenous malformations fed by the striate arteries and lying within the claustrolenticular region can be excised by using microsurgical techniques. Three patients operated on with successful removal of the malformation are discussed here.

Adult↗
PubMed1979

Effect of reperfusion on the uptake of [3H] uridine in the gerbil brain after prolonged ischaemia.

The uptake of labelled uridine is reduced in the whole ischaemic hemispheres of gerbils subjected to unilateral carotid artery occlusion. Following circulatory restoration, brain structures that had an ischaemic insult of moderate intensity exhibit a progressively increased uptake. However, during reperfusion there is a tendency towards a clear cut definition of dead zones. This progression of the lesions seems to be related to a maturation phenomenon occurring in areas with an irreversible damage at the end of the ischaemic period.

Animals↗
PubMed1979

Carotid-choroidal aneurysms: remarks on surgical treatment and outcome.

Seven patients with ruptured carotid-choroidal aneurysms were operated on in a three-year period. The anterior choroidal artery was thought to have been left intact in all cases at the operation. However, postoperative angiography revealed impairment of the choroidal circulation in two cases. These were the only patients who developed postoperative morbidity. Preservation of the anterior choroidal artery seems to be of paramount importance in dealing with carotid-choroidal aneurysms.

Adult↗
PubMed1979

Surgical treatment of arteriovenous malformations of the posterior fossa.

Nine cases of arteriovenous malformations of the posterior fossa were operated upon, using microsurgical techniques. The excision was radical in eight patients. Seven of them, as well as the sole patient who had a partial removal of the malformation, returned to their previous occupations without neurological signs. In one case the preoperative deficit was unchanged. Some lesions that appear to penetrate the brain stem actually lie on its surface and can be dissected through an extrapial plane of cleavage. Extension of the malformation into the cerebellar peduncles requires dissection of the tangle and opening of the IVth ventricle.

Adolescent↗