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Biomedical subjects

A Pau

Publications and source records attributed to A Pau.

98 records · Page 6Linked to original sources

Redundant nerve roots of the cauda equina. A case report.

One further case of redundant nerve roots of the cauda equina is described, and a review of eleven comparable cases in the literature is provided. In the authors' opinion, this disease appears to be a congenital anomaly, frequently but not necessarily associated with spinal changes.

Arachnoiditis↗

Synthesis of N-[4-(propyl)cyclohexyl]-amides with anti-inflammatory and analgesic activities.

Seventeen (un)substituted N-[4-(propyl)cyclohexyl]-amides (6a-h, 7a-h and 8) were synthesized and tested as anti-inflammatory and analgesic agents. The substituents on the aromatic ring were chosen in order to study the influence of electron-withdrawing or electron-donating residues, that change the electronic density on the aromatic moiety. The pharmacological results allow drawing some preliminary considerations on structure-activity relationships.

Amides↗

Long-term survival of a patient with a giant-cell tumor of the sphenoid body: a case report.

Giant-cell tumors (osteoclastomas) of the sphenoid body are rare, histologically benign lesions that can grow in different directions within the bony structures of the skull base. To date, the precise role of the different surgical strategies (radical versus partial resection; biopsy) and of supplementary postoperative radiotherapy remains undefined due to the short follow-up of the majority of the reported cases. We present a patient who is alive without symptoms or signs of recurrence 44 years after a macroscopically radical excision of the neoplasm followed by radiotherapy.

Adult↗

Postoperative "meningocele spurius". Report of two cases.

Two cases of postoperative meningeal pseudocysts are described. Operative or traumatic as well as congenital defects of the meninges seem to be the potential factors leading to the cyst formation. A review of the literature is reported.

Adult↗

Association of aneurysm and arteriovenous malformation on the posterior inferior cerebellar artery. Report of three further cases and review of the literature.

As far as we know, only 20 patients with association of aneurysm and arteriovenous malformation (AVM) on the posterior inferior cerebellar artery (PICA) have been reported so far. Further three personal cases are presented here and the pertinent literature is reviewed, the coexistence of aneurysm(s) and AVM on the PICA district increases the risk of intracranial bleeding compared with patients harbouring this association in the cerebral hemispheres. The direct approach of both lesions (excision of the AVM and clipping of the aneurysm) in one-stage operation is the treatment of choice.

Adult↗