[Thoracolumbar spinal cord astrocytoma with intense calcification. Case report].
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Biomedical subjects
Publications and source records attributed to A Kondo.
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Recently microvascular decompression surgery has been performed for trigeminal neuralgia or glossopharyngeal neuralgia with remarkable success. In differential diagnosis of such neuralgia, a lot of atypical facial pain must be taken into consideration, one of which is so-called Eagle's syndrome. This syndrome is characterized by elongated styloid process or calcified stylohyoid ligament compressing the Vth and/or IXth cranial nerve. In the present paper we report three cases of Eagle's syndrome and discuss the mechanism, differential diagnosis and surgical treatment of the facial pain in this syndrome. The first case was a 40-year-old man. He complained of continuous dull pain on the right face. Sometimes he also suffered from radiating pain into the orbit and maxillary region. A-P and lateral projection of plain skull film showed elongated styloid process measuring about 4.5 cm in length. This process curved medially and was palpable in the tonsillar fossa. Above mentioned radiating pain was released by the injection of local anesthesic agent into the tonsillar fossa. From these findings, diagnosis of Eagle's syndrome was made. He was performed partial styloidectomy by transoral approach with complete relief of the facial pain. The second case was a 49-year-old woman. She complained of continuous or periodic pain that radiating from the right subauricular area to the right neck. Lateral view of plain skull film showed elongation of her right styloid process measuring about 4 cm in length. In the right tonsillar fossa, the elongated styloid process was palpable, compression of which induced radiating pain. By injection of anesthesic material into the right tonsillar fossa the pain disappeared temporarilly.(ABSTRACT TRUNCATED AT 250 WORDS)
An intraoperative recording of a direct compound action potential of the 8th cranial nerve with pre, intra and postoperative monitorings of auditory brainstem evoked response (ABR) was carried out for the purpose of clarifying mechanism and prevention of postoperative hearing dysfunction following microvascular decompression surgery as a treatment for hyperdysfunction syndrome of cranial nerves. In 221 patients with hemifacial spasm and tic douloureux out of 510 patients operated on by microvascular decompression surgery, ABR was monitored before, during and after surgery and furthermore, in the recent 94 patients among them, an intraoperative direct recording of a compound action potential of the acoustic nerve was performed simultaneously. Among these 94 patients, postoperative mild hearing dysfunction was encountered in 11 patients and severe reduction of hearing acuity in 2. As a result of our studies of monitoring action potential of the 8th cranial nerve and ABR, the following conclusions were drawn. When a latency of component V of ABR was delayed by more than 1.5-2.0 msec during surgery, and delay of latency of main negative peak (N1) of an action potential of the acoustic nerve exceeded by more than 1.0 msec, the occurrence rate of postoperative hearing dysfunction became positively high. There were two different types of changes in both ABR and action potentials; one type was a delay of an action potential in combination with that of ABR latencies and the other one was merely a delay in ABR components without following a remarkable change in action potentials. The former change might due to be an insult of whole neural pathways of the 8th cranial nerve including a cochlear nucleus and the latter change may due to be functional changes of the structures proximal to the cochlear nucleus. The delay of latencies in ABR and action potentials could be imposed either by a traction of the 8th cranial nerve or by a compression of the region of cochlear nucleus by a blain spatula as well as a vascular insufficiency of the tiny vessels which supplied these neural structures. To avoid the surgical insult to the acoustic nerve itself and more proximal neural pathways, the traction of any neural structures by a brain spatula should be lasted less than 5 minutes with more than 2 minutes intervals when judged from the results of our monitoring studies and the pressure of the compression on the cerebellar cortex is much preferable to be less than 20 mmHg for the safety throughout whole surgical procedures.
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We report a case of non-hormonal adrenocortical adenoma. The tumor was removed en block with the adrenal gland. The specimen was 5.0 X 4.5 X 3.0 cm, weighed 30 g and was solid. Histologically, this tumor had an oncocytoma-like appearance. However, as there is no concept of oncocytoma in connection with adrenocortical adenoma, this case was diagnosed as adrenocortical adenoma. A case with such histological findings has never been reported.
A 24-year-old female with infected urachal cyst is reported. She was admitted to the hospital with complaints of a lower abdominal mass, abdominal pain and cystitis symptom. Brownish pus discharges from her umbilicus were recognized by manual compression of the lower abdominal mass. Cystoscopy revealed a small orifice at the dome of the bladder, and pus discharges from this orifice. A pooling of contrast medium (8 X 2.5 cm) under the umbilicus was detected by a fistelography from the umbilicus, and a low density mass was detected under the abdominal wall between the umbilicus and the dome of bladder on a CT scan. So she was diagnosed as an infected urachal cyst and operated on. The urachal cyst which was adhered to the peritoneum had penetrated both the umbilicus and bladder at the time of operation. Complete removal of the urachal cyst with partial cystectomy was done. We also reviewed the Japanese case reports of urachal cyst.
In case of the advanced extension into the thoracic cavity, it has been difficult to remove a large thoracic spinal hourglass tumor by conventional laminectomy, even adding costotransversectomy, due to high risk of injuring diverse important vessels and other organs by blind manipulation. A case of a large thoracic spinal hourglass neurinoma with advanced extension into the mediastinum is presented. A 49-year-old female was admitted for the further examination of the left mediastinal tumor, incidentally detected on routine chest roentgenogram, which was suspected as the part of spinal hourglass tumor. Her neurological examination was normal except hyperreflexia of bilateral lower extremities. Plain chest roentgenogram showed a left mediastinal mass behind the aortic arch and the descending aorta, which slightly enlarged in size, compared with its previous size in the chest film taken 3 years ago. Thoracic spine tomogram showed the destruction of the left pedicle of T4, the absorption of posterior aspect of the T4 vertebral body and the dilatation of the left intervertebral foramen between T4-T5. Myelogram showed the complete block of dye column at T4. Metrizamide CT scan revealed the large extradural hourglass tumor, which compressed the dural theca anterolaterally and extended through the dilated left T4-T5 intervertebral foramen into the left mediastinum and attached to the descending aorta. Two stage operation, the first for the removal of the left mediastinal tumor by transthoracic approach and the second for intraspinal canal tumor by posterior approach, was performed with success for this large thoracic spinal hourglass tumor.(ABSTRACT TRUNCATED AT 250 WORDS)
Holding postures to resist uninhibited detrusor contractions are illustrated and discussed. These postures were observed in children with urodynamically proved unstable bladders. The majority of the holding postures involved compressing the urethral meatus or the perineum in girls, or contracting all of the skeletal muscles or squeezing the glans penis in boys. The holding posture required the child to remain still. Younger children used straightforward holding postures, while older children adopted more sophisticated and less recognizable positions. These clinical observations seem to suggest that a physician should probably suspect an unstable bladder in any child who often demonstrates any of these postures.
We report a case of renal hypertension 6 months after a panhysterectomy for cervical cancer. Clinical investigation revealed that recurrent cancer obstructed the left ureter, resulting in the formation of a gigantic perirenal pseudocyst and, subsequently, hypertension. Constriction of the renal parenchyma was responsible for the overactivity of the renin-angiotensin system (the Page phenomenon). Ultrasound-guided percutaneous drainage relieved the symptomatology completely.
2,4-Dienoyl-CoA reductase has been purified to homogeneity from Candida lipolytica cultivated in the presence of linoleic acid. The native enzyme had a molecular weight close to 360,000 as estimated by gel filtration on Sepharose CL-4B, whereas the subunit molecular weight estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis was 33,000. The purified 2,4-dienoyl-CoA reductase from C. lipolytica gave a single precipitin line with antibodies raised against the purified enzyme from C. lipolytica. The general properties of the 2,4-dienyl-CoA reductase from C. lipolytica were examined. The enzyme had optimal pH at 6.5 and was inactivated by heat treatment at 50 degrees C for 10 min. trans-2,trans-4-Octadienoyl-CoA was the most active substrate of the dienoyl-CoA esters examined.
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Autonomic hyperreflexia in 25 patients with spinal cord injury has been clinically analyzed. Nineteen of the patients (76%) suffered from neurogenic lesions above Th-5 and the rest (24%) below Th-6. The most frequent subjective symptom was sweating (22 patients), followed by headache, nausea and so forth. These symptoms were encountered mostly in patients with poor voiding efficiency and developed less than one year after the spinal cord injury. Both systolic and diastolic blood pressure elevated with the distension of the bladder. At the maximum bladder capacity both systolic and diastolic pressure were 39% higher than that observed in the empty bladder. Regitin, 10 mg, given intravenously suppressed this elevation by two-thirds compared to the control. The treatment modality consisted of clean intermittent catheterization and external sphincterotomy, to prevent the over-stretching of the detrusor muscle, together with administration of alpha-adrenergic blockers and ganglionic blocking agent, which interrupt the efferent impulse. Twenty two of the patients (88%) were successfully controlled.
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A case of cervical dural ectasia in von Recklinghausen's disease is reported. A 36-year-old female was admitted to our hospital with complaints of hypesthesia in the extremities and gait disturbance. Plain cervical x-ray films showed dilated interpediculate distance and increased A-P diameter of the cervical spinal canal. Myelography showed abnormally dilated subarachnoid space at C4-C7 level. Metrizamide CT scan also revealed abnormally dilated subarachnoid space, which was at the ventral site of the spinal cord. No tumors, arachnoid cysts, syringomyelia were noticed. From the above-mentioned radiological findings, dural ectasia in von Recklinghausen's disease was suggested. In the discussion, it was emphasized to consider dural ectasia in the differential diagnosis of the dilated spinal canal.
A 42-year-old woman whose hemifacial spasm develops not only involuntarily but also synchronously to the sound stimulation to the left ear is presented. She had about 10 years history of left hemifacial spasm which occurred only involuntarily, and she was treated successfully by microvascular decompression method on June 1982. She had been uneventful and free from facial spasm until around January 1983, about 7 months after the first surgery, when her hemifacial spasm recurred and interestingly enough, this spasm started to occur not only involuntary but also synchronously to stimulation of the sound. On her electromyography (EMG) of the face, high amplitude discharge were noted sporadically during her facial muscle twitching, but more constant and regular high amplitude discharge on EMG were also evoked invariably and synchronously with the sound stimulation which was induced by 90 dB click sound and once this sound stimulation discontinued her facial muscle twitching ceased and abnormal discharge of EMG which appeared with sound stimulation disappeared instantly. On March 18, 1983, her left posterior fossa was explored and another angled artery was found compressing the facial nerve just at the root entry zone, more proximally than the previous site where the nerve was found compressed and decompressed at the first surgery. After complete replacement of this offending artery from the nerve, her facial spasm disappeared completely and was never evoked by the sound stimulation. Her postoperative EMG revealed no abnormal discharges at all after the sound stimulation by click sound in the ear.(ABSTRACT TRUNCATED AT 250 WORDS)