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Biomedical subjects

A Ishida

Publications and source records attributed to A Ishida.

At least 289 records · Page 16Linked to original sources
PubMed1987

[Statistical survey of metastasis of bladder tumors--from the annual of pathological autopsy cases in Japan].

We analyzed 1,821 cases of bladder tumors collected from the Annual of the Pathological Autopsy Cases in Japan, 1978-1982, published by the Japanese Pathological Society to determine the frequency of metastasis and metastatic sites. Study of age distribution revealed that the highest incidence was found in the 70-79 age group and that the male to female ratio was 2.95:1. Histologically, the tumors were transitional cell carcinoma in 1,393 cases (80.5%), squamous cell carcinoma in 185 cases (10.7%), adenocarcinoma in 64 cases (3.7%) and anaplastic cell carcinoma in 62 cases (3.6%). Metastasis was found in 1,275 cases (70.0%). The frequency of metastasis according to histological type was transitional cell carcinoma in 960 (69.8%), squamous cell carcinoma in 127 cases (76.5%), adenocarcinoma in 51 cases (86.4%) and anaplastic cell carcinoma in 53 cases (89.8%). Metastasis occurred in order of decreasing frequency in lymph nodes, lungs, liver, bones, peritoneum, kidneys, intestines, prostate, ureters and uterus. These findings were compatible with several previous statistical surveys of autopsy cases of bladder tumor.

Adenocarcinoma↗
PubMed1987

[An autopsy case of untreated bladder cancer].

A case of untreated bladder cancer with an unusual clinical course in a 48-year-old man is reported. The patient noted painless gross hematuria 10 months prior to the first visit to our department on May 16, 1980. Cystoscopy revealed nonpapillary tumors in the right lateral and posterior wall. The histopathological finding was transitional cell carcinoma, grade II on biopsy. No metastatic lesions were found on clinical evaluation. Therefore, radical cystectomy with ileal conduit was planned. However, the patient refused the operation because he could not tolerate having the stoma on the abdomen. Because the patient had no complaint except for the past gross hematuria, he refused any treatment. The patient revisited our department 6 months after the diagnosis because swelling of the right thigh caused gait disturbance. A chest X-ray revealed pleural effusion, and an excretory urogram disclosed a right non-visualizing kidney and a large filling defect in the bladder. Cervical lymph nodes were swollen and several small nodules under reddish skin on the chest and abdomen were found to be metastatic lesions. Chemotherapy with cis-diamminedichloroplatinum, doxorubicin and 5-fluorouracil was ineffective in regressing the primary tumor although cervical lymph nodes and skin lesions responded at the induction. The patient died 29 months after the initial onset of the gross hematuria and 19 months after the diagnosis. Autopsy findings revealed metastasis in skin, diaphragm, left adrenal gland, stomach, small intestine, pericardium, right epididymis and lymph nodes.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1986

Recruitment threshold force and its changing type of motor units during voluntary contraction at various speeds in man.

The motor unit discharges in human hand muscles were recorded during voluntary isometric contraction. Bipolar wire electrodes were inserted in the right adductor pollicis muscle (AP) and first dorsal interosseous muscle (FDI) for the recordings. Motor unit activities from these muscles were investigated when subjects exerted voluntary force to each target force at various speeds. On 27 motor units of AP and 28 motor units of FDI, ramp RTF and ballistic RTF were compared. Furthermore, RTF changes of motor units with the different force speeds were investigated. It is clear that the RTF of the motor units during ballistic contractions were lower than those during ramp contraction. The processes of motor unit RTF changes were classified into 3 types: RTF of type I motor units were relatively low and decreased slightly even when force speed increased widely; RTF of type II motor units were relatively high and decreased irregularly; and RTF of type III motor units, which appeared rarely, decreased their relatively high RTF with increases of force speed increment. It is suggested that the volitional outflow related with the force speed change to the spinal motor pool might cause the different RTF change effects in the various motor units.

Action Potentials↗
PubMed1986

Portable limb-load monitor utilizing a thin capacitive transducer.

We describe a self contained electronic device for controlling the limb loads exerted by patients having one affected foot and using a walking aid. The device measures the limb load with a thin capacitative transducer attached to the sole of the patient's shoe, and operates in two basic modes. In the first mode the device compares the load with two preset thresholds and emits audible feedback tones to guide the patient in maintaining the required load on his affected foot; a low frequency tone when the load falls between the two thresholds, and a high frequency tone when the load exceeds the upper threshold. Experimental results demonstrate the effectiveness of the device in controlling the limb load in the first mode. In the second mode, only one threshold is preset. When the load exceeds that threshold and is maintained above this level for a period longer than a selected stance-duration time, a low-frequency tone is generated.

Adult↗
PubMed1986

[Reversible ischemic myocardial damage: clinical observation using two-dimensional echocardiography].

Acute myocardial ischemia followed by protracted asynergy and subsequent resolution was defined as reversible ischemic myocardial damage. The purpose of this study was to confirm the existence of this entity and to illustrate the clinical features. The subjects consisted of 26 patients with typical acute myocardial ischemia who satisfied the above definition, and serial changes in left ventricular wall motion were observed by two-dimensional echocardiography. The left ventricle was divided into 11 segments and the movement was scored according to the dynamic behavior of each segment by five points ranging from normal (0) to dyskinesis (4), and evaluated semiquantitatively using the total score sum as the total asynergy score. Compared to the initial value, this score decreased to 57% after one week, 38% in two weeks, 22% in three weeks and 17% in four weeks. The asynergy persisted 23.7 +/- 13.5 days and ranged from two days to three months. The peak CPK ranged from 32 to 561 IU (mean 212 +/- 157 IU). Coronary arteriography revealed undisturbed flow of the responsible artery in both acute and chronic phases including four cases of successful PTCR. Comparison of the electrocardiographic changes and asynergy showed that diminished R wave amplitude, ST segment elevation and inverted T waves are frequently associated with persistence of asynergy, extensive asynergy can even occur in cases without a diminished R wave or abnormal Q wave and when asynergy resolves, ST segments tend to return to the baseline, but T wave inversion commonly persists. A transient Q wave was observed in 38% of the patients examined. The electrocardiogram became normal in an average of 111.3 +/- 75 days. In conclusion, there is a subgroup of reversible asynergy among cases of unstable angina pectoris or subendocardial infarction. The mechanism for this may be myocardial "stunning" following transient transmural ischemia. Recognition of this fact seems very important in the diagnosis and treatment of acute myocardial ischemia.

Adult↗
PubMed1985

[Giant liposarcoma of the spermatic cord: report of a case].

We report a case of a 3,100 g giant liposarcoma of the spermatic cord in an 88-year-old man. The tumor had been present for 13 years. The pathological diagnosis was well-differentiated liposarcoma of sclerosing type. Twenty-two cases of spermatic cord liposarcoma found in the Japanese literature were reviewed. This case was thought to be of the largest tumor and oldest patient in the Japanese literature.

Aged↗