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Biomedical subjects

A Hjortrup

Publications and source records attributed to A Hjortrup.

At least 73 records · Page 4Linked to original sources
PubMed1985

Influence of diabetes mellitus on operative risk.

In a retrospective study postoperative morbidity was compared between 224 patients with diabetes mellitus and 224 non-diabetic control patients matched with regard to operative procedure (major vascular, abdominal and acute surgery for hip fracture), sex, age, complicating cardiovascular disease and weight. Forty-six patients in each group had complications, without any trend towards specific morbidity in the diabetic group. Incidence of morbidity was similar in diabetic patients treated with insulin, oral antidiabetic agents or diet. Diabetic patients with complications had significantly (P less than 0.01) lower blood glucose pre- and postoperatively than those without complications. The risk of overlooking (type II error) a 25 per cent increase in complication rate in the diabetic patients was less than 10 per cent and the risk of overlooking a 50 per cent increase in morbidity less than 0.5 per cent. These results do not support the common belief that diabetes per se may increase surgical risk.

Aged↗
PubMed1985

Morbidity after femoral neck fracture not increased in diabetics.

In a retrospective study the morbidity following surgery for femoral neck fracture was investigated in 81 patients with diabetes mellitus and in 81 non-diabetic matched control patients. Sixteen patients in each group had postoperative complications with no tendency to specific complications in the diabetic patients. Morbidity was equally distributed between patients treated with insulin, antidiabetic agents, and diet. Our results do not support the common belief that there is an increased postoperative risk in diabetic patients.

Aged↗
PubMed1985

Lesser sac hernia.

A rare case of mesocolic hernia containing the descending colon is described in a 71-year-old man. The literature on lesser sac hernia is briefly reviewed and the pathogenesis symptoms and treatment are discussed.

Aged↗
PubMed1985

Morbidity in diabetic and nondiabetic patients after abdominal surgery.

Morbidity after abdominal surgery was retrospectively investigated in 79 patients with diabetes mellitus and in 79 nondiabetic controls matched for type of surgery (biliary, gastric or colonic), sex, age, body weight and complicating cardiovascular disease. There were 20 complications (including 2 in each of 4 patients) in the diabetic group and 18 (2 patients with 2 complications) among the controls, with no tendency to specific complications in the diabetics. The difference in complication rate was not statistically significant. The mean blood glucose level preoperatively and in the first four postoperative days did not differ significantly between the diabetics with and those without postoperative complications. The risk of overlooking (type II error) a 25% heightened complication rate among the diabetic patients was calculated to be less than 30%, and the risk of overlooking a 50% increase was less than 8%. The authors conclude that elective abdominal surgery in diabetic patients is not burdened by clinically significant increase of postoperative morbidity.

Adult↗
PubMed1984

Early reclosure versus conventional secondary suture of severe wound abscesses following laparotomy.

The study comprised 81 consecutive cases of severe incisional abscesses following laparotomy during a 28-month period. Severe incisional abscess was defined as wound infection necessitating opening of the entire wound down to the fascia. During the first 12 months of the study period, 30 patients had conventional secondary suture with a median time of 12 days from drainage of wound abscesses until closure of clean and granulating wounds. During the last 16 months, 51 patients had early closure of contaminated wounds 4 days after drainage under systemic antibiotic cover with clindamycin. The surgical technique used in early closure allowed complete occlusion of the wound cavity without sutures in the wound itself. Recurrent incisional infection occurred in 3 of 30 patients having secondary suture and in 1 of 51 having early reclosure. It is concluded that early reclosure under systemic antibiotic cover is a safe procedure, which reduces hospitalization and convalescence.

Abscess↗
PubMed1984

Sexual dysfunction after low anterior resection for midrectal cancer.

Forty-nine patients under the age of 65 years, who had a low anterior resection performed for cancer of the midrectum, were interviewed. Eight patients were sexually inactive before the operation and were excluded. Postoperatively thirty-five had normal sexual function. Two male patients developed transient erectile impotence while two female patients had given up active sexual life after the operation because of dyspareunia. Two patients, one male and one female had permanent impairment. It is concluded, that severe sexual dysfunction can be seen after low anterior resection for cancer, but no early conclusion about permanent sexual dysfunction should be drawn.

Adult↗
PubMed1984

A modified technique for stapled anastomosis after the Hartmann procedure.

In 15 patients the intestinal continuity after Hartmann's operation was restored by a stapling technique which facilitates anastomosis without mobilization of the 'blind' rectal stump. No signs of anastomotic leak was observed, and at follow-up 6-12 months later there were no strictures.

Acute Disease↗
PubMed1983

New approach to treatment of severe incisional abscesses following laparotomy. Wound closure under systemic antibiotic cover four days after drainage.

Forty consecutive patients who developed subcutaneous abscesses after intraperitoneal operations were treated by incision and drainage followed by suture of the wound four days later under antibiotic cover. The wound was closed by means of interrupted Prolene sutures. No sutures were placed in the wound cavity, and no drain was applied. The antibiotic used was clindamycin 600 mg intravenously peroperatively and 150 mg every six hours for four days.

Abscess↗
PubMed1983

Strictures of the male urethra treated by the Otis method.

During a 5-year interval 72 consecutive patients with urethral strictures were treated by internal urethrotomy according to the method of Otis. The etiology, surgical technique, complications and postoperative management are discussed. The results after a mean followup of 29 months showed an over-all success rate of 82 per cent (95 per cent confidence limits 71 to 90 per cent). It is concluded that internal urethrotomy should be considered for primary treatment of urethral strictures, since the procedure is easy and complications are few.

Adult↗
PubMed1983

Value of the 30-minute adrenocorticotropin (ACTH) test in demonstrating hypothalamic-pituitary-adrenocortical insufficiency after acute ACTH deprivation.

Adrenocortical responsiveness to corticotropin was reestablished by daily administration of 1 mg ACTH depot for 4 days in seven patients with secondary adrenocortical insufficiency. Peak plasma cortisol concentrations during a 30-min ACTH test performed 2 days after stopping injection of ACTH depot increased in all seven subjects (they were normal in five subjects) compared to the initial subnormal responses. Repeated short ACTH tests 5, 8, and 12 days after the last administration of ACTH depot showed a gradual decrease in plasma cortisol responses. When tested 8 days after the last ACTH depot injection was given all seven patients again had a subnormal response to ACTH. Thus, acute ACTH deprivation leads to an impaired adrenocortical response at a short ACTH test within 8-12 days.

Adrenal Cortex↗