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Biomedical subjects

A Hjortrup

Publications and source records attributed to A Hjortrup.

At least 55 records · Page 3Linked to original sources
PubMed1988

Adrenocortical function in old age as reflected by plasma cortisol and ACTH test during the course of acute myocardial infarction.

Adrenocortical function, as reflected by sequential analysis of plasma cortisol and adrenocorticotropin (ACTH) test, was investigated in elderly patients (greater than or equal to 65 years) with acute myocardial infarction (AMI), and compared to young patients (less than or equal to 55 years) with AMI. Further, age-matched subjects admitted with ischaemic chest pain, in whom AMI was not verified, served as controls. Following infarction, plasma cortisol peaked within 24 hours in both age groups, whereupon the cortisol level gradually decreased till day 12. Plasma cortisol during AMI disclosed no age-related difference, but was significantly correlated to the localization of infarction and lactate dehydrogenase (LDH). The development of complications, i.e. hypotension, congestive heart failure, and arrhythmia, calling for therapeutic intervention, was solely correlated to infarct size, as estimated by peak LDH. Young and elderly patients responded equally and normally to ACTH stimulation, and in both groups a significant, positive correlation between the basal and the 30-min plasma cortisol was observed. Thus, we may conclude that in patients with AMI, the hypothalamic-pituitary-adrenocortical (HPA) response to stress and ACTH test shows no repression due to age.

Adrenal Cortex Function Tests↗
PubMed1988

Evaluation of ileorectal anastomosis for the treatment of ulcerative proctocolitis.

Of 327 patients treated for ulcerative proctocolitis, 165 underwent surgery and an ileorectal anastomosis was performed in 59: 19 of these patients were operated upon in one stage and 40 in two stages. In 13 cases the anastomoses had to be converted, 5 during the initial hospitalization and 8 during a later admission. Three patients developed carcinoma of the rectal stump. The median follow-up period was 15 years. It is concluded that ileorectal anastomosis has a place in the treatment of inflammatory bowel disease, but requires careful follow up of the patients.

Anastomosis, Surgical↗
PubMed1988

Medical treatment of stomal ulcers.

Thirty-five patients with anastomotic ulcer after gastric resection for benign ulcer disease were treated with sucralfate (Antepsin) and endoscopically controlled over a 6-month period after termination of the medical treatment. The healing frequency of 75% makes this model a suitable alternative in the treatment of stomal ulcers.

Adult↗
PubMed1987

Non-sutured fibrin adhesive vs. sutured anastomosis. A comparative intra-individual study in dog colon.

In each of ten dogs the colon was subjected to a two-layered sutured anastomosis and a non-sutured fibrin adhesive anastomosis. Intra-individual comparisons showed no significant difference of in vivo bursting strength after 7 days between the colon segments with sutured and those with non-sutured anastomoses. Under experimental conditions it was thus possible to achieve a safe, sutureless anastomosis in the colon using only fibrin adhesive.

Anastomosis, Surgical↗
PubMed1987

Volvulus of the cecum.

Twenty-six cases are reported of ileo-cecal volvulus admitted to three community hospitals over a period of six years. The operative management of ileo-cecal volvulus is discussed. Based on the results and review of the literature the authors recommend a right hemicolectomy in the presence of gangrene or perforation, in other cases a cecopexia with fixation in combination with intestinal tube decompression when needed.

Adult↗
PubMed1986

Fibrin adhesive versus sutured anastomosis: a comparative intraindividual study in the small intestine of pigs.

The small intestine in each of ten pigs was subjected to three anastomoses: one sutured anastomosis and two non-suture fibrin adhesive anastomoses in an intra-individual controlled comparison. There was no significant difference in the in vivo bursting strength after 7 days. Thus, the two types of anastomoses were of equal strength. It is concluded that it appears possible to achieve a safe sutureless anastomosis in the small intestine, with fibrin adhesive alone.

Animals↗
PubMed1986

Reduction of post-operative bleeding after transurethral resection of the prostate by local instillation of fibrin adhesive (Beriplast).

A method for instilling a two-component fibrin adhesive into the prostatic cavity after transurethral resection of the prostate is described. In a prospective, controlled study, 30 consecutive patients undergoing transurethral prostatectomy (TURP) were randomised either to receive treatment with the local instillation of fibrin adhesive into the prostatic cavity or to a control group that received no special treatment post-operatively. There were no complications either during application of the fibrin adhesive or in the follow-up period. Post-operative blood loss was significantly reduced in the fibrin group (P less than 0.01).

Fibrin↗
PubMed1986

A long-term gastrointestinal follow-up in patients operated on for congenital hypertrophic pyloric stenosis.

A gastrointestinal follow-up of 91 patients operated on for congenital hypertrophic pyloric stenosis (CHPS) between 1942 and 1964, using the Fredet-Ramstedt method, is presented. Among 85 patients available for follow-up, 72 responded to a request for reexamination. These patients were interviewed personally by one of the authors. Thirty-four patients (47%) consented to have a Roentgen examination done, performed as a double contrast study, investigating the structure and function of the stomach and duodenum. Forty-two patients (58%) had varying minor gastrointestinal complaints. Only two patients had severe symptoms. X-ray examination in 34 patients (47%) showed only three with pathological changes, i.e. one with mild deformation of the duodenal bulb, another with slight duodenal reflux. The third X-ray showed massive gastric retention with duodenal bulb deformation. The patient suffered from severe dyspepsia and vomitus. No correlation was found between the severity of the CHPS and the presence of later gastrointestinal symptoms. It is concluded that the Fredet-Ramstedt's operation for CHPS is an efficious operation with few perioperative complications and good long-term results.

Adult↗
PubMed1986

Tissue adhesives and intestinal anastomosis.

This article presents a review of the literature concerning the employment of tissue adhesives in the production of intestinal anastomoses. The fibrin adhesive is the tissue adhesive of choice in as much as it is physiological does not possess histotoxicity or cause allergic reactions. Fibrin adhesive sealing of a conventional sutured anastomosis might improve this anastomosis as it reduced the postoperative mortality-rate significantly in a prospective study with a retrospectively matched control group comparing sealing and no sealing, but prospective, randomized trials are lacking. Finally a cyanoacrylate intestinal anastomosis has proved obsolete as in experimental trials it has proved inferior to the conventional anastomosis.

Animals↗
PubMed1986

Surgical treatment of ureteric stones.

638 patients with ureteric stones have been evaluated. 174 patients (28%) were selected for surgical treatment. 129 out of the 174 patients initially underwent open surgery. In the other 45 patients the initial treatment was stone extraction by the Dormia technique after which 27 stones were removed successfully. In the remaining 18 patients catheterisation of the ureter was performed, after which stones passed spontaneously in 15 patients. In one patient the stone was removed by another attempt with the Dormia procedure and two patients underwent operation. At follow-up 4-6 weeks after the diagnosis of ureteric stones was made, no signs of stones were found by urography in either the 464 patients (72%) who never underwent any surgical procedure or in the patients treated by open surgery or other procedures. It is concluded that parameters such as degree of ureteric obstruction, infection, pain and stones not passed within 6 weeks are important factors in selection of patients for operation.

Adolescent↗